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Q6C3E0 (GLNA_YARLI) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

Short name=GS
EC=6.3.1.2
Alternative name(s):
Glutamate--ammonia ligase
Gene names
Name:GLN1
Ordered Locus Names:YALI0F00506g
OrganismYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) [Reference proteome]
Taxonomic identifier284591 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homooctamer By similarity.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 364364Glutamine synthetase
PRO_0000153165

Sequences

Sequence LengthMass (Da)Tools
Q6C3E0 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 142A5AB8D81FA7FC

FASTA36440,715
        10         20         30         40         50         60 
MVLSKYLDLP QHGAVLAEYI WIDAHFNIRS KCKTLDKKPT SIEDLPEWNF DGSSTDQAPG 

        70         80         90        100        110        120 
HDSDIYLRPA AIYPDPFRRG DNIIVLAECW NNDGTPNKFN HRHECAKLMS AHEKEVIWFG 

       130        140        150        160        170        180 
IEQEYTMFDE SDNPVGWPKG GFPAPQGPYY CGVGTGKVFA RDVVEAHYRA CLYSGINISG 

       190        200        210        220        230        240 
INAEVMPSQW EYQVGPCEGI SMADELWMSR YLLHRVAEEF GIKISFHPKP LQGDWNGAGC 

       250        260        270        280        290        300 
HTNVSTKSMR EPGGMKHIEA AIEKLAARHK EHIAVYGEDN DMRLTGRHET GSIGSFSSGV 

       310        320        330        340        350        360 
ANRGCSIRIP RSVAKEGYGY FEDRRPASNI DPYLVTGIMT ETICGSIPDA DMVEETKRGE 


EEGF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382132 Genomic DNA. Translation: CAG77624.1.
RefSeqXP_504822.1. XM_504822.1.

3D structure databases

ProteinModelPortalQ6C3E0.
SMRQ6C3E0. Positions 5-344.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4952.Q6C3E0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCAG77624; CAG77624; YALI0_F00506g.
GeneID2908248.
KEGGyli:YALI0F00506g.

Phylogenomic databases

eggNOGCOG0174.
HOGENOMHOG000061500.
KOK01915.
OMAGTPYGWP.
OrthoDBEOG7GTTD8.

Family and domain databases

Gene3D3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
PROSITEPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA_YARLI
AccessionPrimary (citable) accession number: Q6C3E0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: August 16, 2004
Last modified: November 13, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families