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Q6C211 (Q6C211_YARLI) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Adenosylhomocysteinase RuleBase RU000548
EC=3.3.1.1 RuleBase RU000548
Gene names
Ordered Locus Names:YALI0F11759g
OrganismYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifier284591 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Dipodascaceae › Yarrowia

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine. RuleBase RU000548

Cofactor

NAD By similarity. RuleBase RU000548

Pathway

Amino-acid biosynthesis; homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1. RuleBase RU000548

Sequence similarities

Belongs to the adenosylhomocysteinase family. RuleBase RU004166

Ontologies

Keywords
   Biological processOne-carbon metabolism RuleBase RU000548
   LigandNAD RuleBase RU000548
   Molecular functionHydrolase RuleBase RU000548
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processone-carbon metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionadenosylhomocysteinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site581Substrate By similarity PIRSR PIRSR001109-1
Binding site1341Substrate By similarity PIRSR PIRSR001109-1
Binding site1591Substrate By similarity PIRSR PIRSR001109-1
Binding site1891Substrate By similarity PIRSR PIRSR001109-1
Binding site1931Substrate By similarity PIRSR PIRSR001109-1

Sequences

Sequence LengthMass (Da)Tools
Q6C211 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: B93426294093A40A

FASTA44949,027
        10         20         30         40         50         60 
MSAPASNYKV ADIGLAAFGR KEIELAENEM PGLMQTREKY AAVQPLKGAR IAGCLHMTIQ 

        70         80         90        100        110        120 
TAVLIETLVA LGAEVTWSSC NIFSTQDHAA AAIAAAGVPV FAWKGETEEE YNWCIEQQLK 

       130        140        150        160        170        180 
AFKDGKKLNM ILDDGGDLTT LVHEKYPEQL DDCFGLSEET TTGVHHLYRM MKEGKLKVPA 

       190        200        210        220        230        240 
INVNDSVTKS KFDNLYGCRE SLIDGIKRAT DVMIAGKTAV VAGFGDVGKG CAQALQSFGA 

       250        260        270        280        290        300 
RVIVTEIDPI NALQASVSGY QVLPMEEACK VGQIFVTTTG CRDIITGEHF SQMPNDAIVC 

       310        320        330        340        350        360 
NIGHFDIEID VAWLKANAKN VVNIKPQVDR FEMPSGRHVI LLAEGRLVNL GCATGHSSFV 

       370        380        390        400        410        420 
MSCSFTNQVL AQIALFNAKN DEFRKKHVEF AKSGPFEVGV HVLPKILDEE VARLHLDHLG 

       430        440 
VKLSKLSDVQ AEYLGIAQEG PYKADIYRY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382132 Genomic DNA. Translation: CAG78108.1.
RefSeqXP_505301.1. XM_505301.1.

3D structure databases

ProteinModelPortalQ6C211.
SMRQ6C211. Positions 8-449.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6C211.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2908635.
GenomeReviewsGene locus YALI0F11759g in contig CR382132_GR.
KEGGyli:YALI0F11759g.

Phylogenomic databases

eggNOGfuNOG06806.
HOGENOMHBG352029.
OMASAQVWVT.
OrthoDBEOG41G6CK.

Family and domain databases

HAMAPMF_00563. AdoHcyase.
[Tree]
InterProIPR000043. Adenosylhomocysteinase.
IPR015878. Ado_hCys_hydrolase_NAD-bd.
IPR020082. S-Ado-L-homoCys_hydrolase_CS.
[Graphical view]
KOK01251.
PANTHERPTHR23420. Ad_hcy_hydrolase. 1 hit.
PfamPF05221. AdoHcyase. 1 hit.
PF00670. AdoHcyase_NAD. 1 hit.
[Graphical view]
PIRSFPIRSF001109. Ad_hcy_hydrolase. 1 hit.
SMARTSM00996. AdoHcyase. 1 hit.
SM00997. AdoHcyase_NAD. 1 hit.
[Graphical view]
TIGRFAMsTIGR00936. AhcY. 1 hit.
PROSITEPS00738. ADOHCYASE_1. 1 hit.
PS00739. ADOHCYASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6C211_YARLI
AccessionPrimary (citable) accession number: Q6C211
Entry history
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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