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Q6C1W9 (TRM10_YARLI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA (guanine(9)-N1)-methyltransferase

EC=2.1.1.221
Alternative name(s):
tRNA methyltransferase 10
tRNA(m1G9)-methyltransferase
Short name=tRNA(m1G9)MTase
Gene names
Name:TRM10
Ordered Locus Names:YALI0F12771g
OrganismYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifier284591 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNAs By similarity.

Catalytic activity

S-adenosyl-L-methionine + guanine9 in tRNA = S-adenosyl-L-homocysteine + N(1)-methylguanine9 in tRNA.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence similarities

Belongs to the RNA methyltransferase TrmD family. TRM10 subfamily.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
Nucleus
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 371371tRNA (guanine(9)-N1)-methyltransferase
PRO_0000060519

Regions

Compositional bias318 – 36851Glu-rich

Sequences

Sequence LengthMass (Da)Tools
Q6C1W9 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: DB7E85996247F4CB

FASTA37141,649
        10         20         30         40         50         60 
MVDVTEPVAP VEAVKETAGA SSATPEVDRT SEPHPKNPQN VPAPYNTKTA VIPEGMSKNE 

        70         80         90        100        110        120 
WKKAQKKAIW ESKKDEIAAV KKEKKKAARK RKQLAISRGE IPAPIPQDER PPQTQLPISI 

       130        140        150        160        170        180 
VLDCGFDEMM TQKEKVSLSA QVGRCYSANR KADARFDLTV NSFNKGLKDR FNNEMNKVHE 

       190        200        210        220        230        240 
LWTNIKFVED DYTVPEDETA KSKLVYLSSD SDNVINELED GKTYIIGGIV DKGRYKNLCQ 

       250        260        270        280        290        300 
DKASKQGLQT GRLPIADFIK LSGRKVLTTN HVFEILLKWT ELKDWKAAFE AVLPMRKLDP 

       310        320        330        340        350        360 
ANYGRAHRRA RKKARLAEGA EGNDEEDDED DDDEEEEEEE SVSAEPEVVE TKAEVETDTE 

       370 
TKAETEAETK A 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382132 Genomic DNA. Translation: CAG78150.1.
RefSeqXP_505343.1. XM_505343.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ6C1W9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2908201.
GenomeReviewsGene locus YALI0F12771g in contig CR382132_GR.
KEGGyli:YALI0F12771g.

Phylogenomic databases

eggNOGfuNOG04600.
HOGENOMHBG717479.
OMAGAFVDHN.
OrthoDBEOG48D43Z.

Family and domain databases

InterProIPR016009. tRNA_m1G_MeTrfase.
IPR007356. tRNA_m1G_MeTrfase_euk.
[Graphical view]
KOK15445.
PANTHERPTHR13563. DUF425. 1 hit.
PfamPF01746. tRNA_m1G_MT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRM10_YARLI
AccessionPrimary (citable) accession number: Q6C1W9
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: August 16, 2004
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families