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Reviewed, UniProtKB/Swiss-Prot Q6BZA0 (ALO_DEBHA)

Last modified February 9, 2010. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    D-arabinono-1,4-lactone oxidase
      Short name=ALO
    EC=1.1.3.37
Alternative name(s):
    L-galactono-gamma-lactone oxidase
Gene names
Name: ALO1
Ordered Locus Names: DEHA2A02904g
OrganismDebaryomyces hansenii (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier4959 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeDebaryomyces

Protein attributes

Sequence length557 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2.

Cofactor

FAD By similarity.

Pathway

Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.

Subcellular location

Mitochondrion membrane By similarity. Note: Membrane-embedded By similarity.

Sequence similarities

Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

Contains 1 FAD-binding PCMH-type domain.

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processbiosynthetic process

Inferred from electronic annotation. Source: InterPro

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentmitochondrial membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionD-arabinono-1,4-lactone oxidase activity

Inferred from electronic annotation. Source: EC

FAD binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 557557D-arabinono-1,4-lactone oxidase
PRO_0000128166

Regions

Domain26 – 209184FAD-binding PCMH-type

Amino acid modifications

Modified residue631Tele-8alpha-FAD histidine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6BZA0-1 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: D2AEE1175CCECE73

FASTA55763,709
        10         20         30         40         50         60 
MRSDIPETLQ NFVSTKTVHQ TWAKTFFCKP QAIFQPRTVD EIRELVDQAR INGKTIMTVG 

        70         80         90        100        110        120 
SGHSPSDMTM TKEWLCNLDR FNQVLKKEEF SGPTRNGEGE EVKFVDLTVQ AGCRIYELNR 

       130        140        150        160        170        180 
YLKENELAIQ NLGSISDQSM AGVISTGTHG STQYHGLVSQ QVVSIEIMNS AGKLITCSSM 

       190        200        210        220        230        240 
ENTQLFKAAM LSLGKIGIIT HVTLRTIPKY TIKSKQEIIK FDTLLKNWDT VWLDSEFIRV 

       250        260        270        280        290        300 
WWFPYSGNCV CWRASKSSEP LSKPRDSWYG TWFGRKFYES LLWISVHICP HLTPLIEKFV 

       310        320        330        340        350        360 
FKNQYGDVET LGHGDVAVQN SVEGLNMDCL FSQFVNEWST PLSSGQDVLI KLNDVIQTAR 

       370        380        390        400        410        420 
EQNRFYVHAP IEVRCSNLTY SEKPFVDEND EPSLYPNKKW LAKRDRLSPG PIPGNNLRPY 

       430        440        450        460        470        480 
LDNSSNLRYD GDGANVTNDQ LTLFINATMY RPFHTNVNSQ EWYQLFEDIM TNASGRPHWA 

       490        500        510        520        530        540 
KNFIGVNGAH RTDQDLRKQL EFGGKTSYSM KGFNPILKKW FGENLVEYNK VRESMDPDNV 

       550 
FLSGKDWAVR NGILIDV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382133 Genomic DNA. Translation: CAG84421.2.
RefSeqXP_456469.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2899772.
GenomeReviewsGene locus DEHA2A02904g in contig CR382133_GR.
KEGGdha:DEHA0A03377g.

Phylogenomic databases

eggNOGfuNOG04297.
HOGENOMHBG323831.
OMADCLFSQF.
OrthoDBEOG91ZGT8.

Enzyme and pathway databases

BRENDA1.1.3.37. 74267.

Family and domain databases

InterProIPR007173. ALO.
IPR016166. FAD-bd_2.
IPR010031. FAD_lactone_oxidase.
IPR006094. Oxid_FAD_bind_N.
IPR006093. Oxy_OxRdtase_FAD_BS.
[Graphical view]
PfamPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR01678. FAD_lactone_ox. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
PS00862. OX2_COVAL_FAD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALO_DEBHA
AccessionPrimary (citable) accession number: Q6BZA0
Entry history
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: December 16, 2008
Last modified: February 9, 2010
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents