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Q6BZA0 (ALO_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-arabinono-1,4-lactone oxidase

Short name=ALO
EC=1.1.3.37
Alternative name(s):
L-galactono-gamma-lactone oxidase
Gene names
Name:ALO1
Ordered Locus Names:DEHA2A02904g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces

Protein attributes

Sequence length557 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2.

Cofactor

FAD By similarity.

Pathway

Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.

Subcellular location

Mitochondrion membrane By similarity. Note: Membrane-embedded By similarity.

Sequence similarities

Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

Contains 1 FAD-binding PCMH-type domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 557557D-arabinono-1,4-lactone oxidase
PRO_0000128166

Regions

Domain26 – 209184FAD-binding PCMH-type

Amino acid modifications

Modified residue631Pros-8alpha-FAD histidine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6BZA0 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: D2AEE1175CCECE73

FASTA55763,709
        10         20         30         40         50         60 
MRSDIPETLQ NFVSTKTVHQ TWAKTFFCKP QAIFQPRTVD EIRELVDQAR INGKTIMTVG 

        70         80         90        100        110        120 
SGHSPSDMTM TKEWLCNLDR FNQVLKKEEF SGPTRNGEGE EVKFVDLTVQ AGCRIYELNR 

       130        140        150        160        170        180 
YLKENELAIQ NLGSISDQSM AGVISTGTHG STQYHGLVSQ QVVSIEIMNS AGKLITCSSM 

       190        200        210        220        230        240 
ENTQLFKAAM LSLGKIGIIT HVTLRTIPKY TIKSKQEIIK FDTLLKNWDT VWLDSEFIRV 

       250        260        270        280        290        300 
WWFPYSGNCV CWRASKSSEP LSKPRDSWYG TWFGRKFYES LLWISVHICP HLTPLIEKFV 

       310        320        330        340        350        360 
FKNQYGDVET LGHGDVAVQN SVEGLNMDCL FSQFVNEWST PLSSGQDVLI KLNDVIQTAR 

       370        380        390        400        410        420 
EQNRFYVHAP IEVRCSNLTY SEKPFVDEND EPSLYPNKKW LAKRDRLSPG PIPGNNLRPY 

       430        440        450        460        470        480 
LDNSSNLRYD GDGANVTNDQ LTLFINATMY RPFHTNVNSQ EWYQLFEDIM TNASGRPHWA 

       490        500        510        520        530        540 
KNFIGVNGAH RTDQDLRKQL EFGGKTSYSM KGFNPILKKW FGENLVEYNK VRESMDPDNV 

       550 
FLSGKDWAVR NGILIDV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382133 Genomic DNA. Translation: CAG84421.2.
RefSeqXP_456469.2. XM_456469.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4959.Q6BZA0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2899772.
KEGGdha:DEHA2A02904g.

Phylogenomic databases

eggNOGCOG0277.
HOGENOMHOG000204635.
KOK00107.
OMAMDCLFSQ.
OrthoDBEOG7JX3CZ.

Enzyme and pathway databases

UniPathwayUPA00771; UER00766.

Family and domain databases

Gene3D3.30.43.10. 1 hit.
3.30.465.10. 1 hit.
InterProIPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR010031. FAD_lactone_oxidase.
IPR023595. LGO_GLO.
IPR006094. Oxid_FAD_bind_N.
IPR006093. Oxy_OxRdtase_FAD_BS.
[Graphical view]
PfamPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
PIRSFPIRSF000136. LGO_GLO. 1 hit.
SUPFAMSSF56176. SSF56176. 1 hit.
TIGRFAMsTIGR01678. FAD_lactone_ox. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
PS00862. OX2_COVAL_FAD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALO_DEBHA
AccessionPrimary (citable) accession number: Q6BZA0
Entry history
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: December 16, 2008
Last modified: November 13, 2013
This is version 68 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways