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Q6BYP7 (SSU72_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

Short name=CTD phosphatase SSU72
EC=3.1.3.16
Alternative name(s):
Suppressor of SUA7 protein 2 homolog
Gene names
Name:SSU72
Ordered Locus Names:DEHA2A07854g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces

Protein attributes

Sequence length223 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1) By similarity.

Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subunit structure

Component of the cleavage and polyadenylation factor (CPF) complex By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the SSU72 phosphatase family.

Ontologies

Keywords
   Biological processmRNA processing
   Cellular componentNucleus
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 223223RNA polymerase II subunit A C-terminal domain phosphatase SSU72
PRO_0000255608

Sequences

Sequence LengthMass (Da)Tools
Q6BYP7 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: 8F927BA73D58F7DA

FASTA22325,813
        10         20         30         40         50         60 
MVSDSLKICT VCAANNNRSM ESHKQLKDAG YNVRSFGTGS AVRLPGPSVD KPNVYEFGTP 

        70         80         90        100        110        120 
YDDIYRDLTS QEYHKMYESN GLIRMINRNR HIKRAPEKWH NNASAGKFDL VITCEERCFD 

       130        140        150        160        170        180 
LVLDDLMVRL VNKDQADTEI KQAVHIINID IKDDYENAVI GGKGILKLVN MIHEFRNTNK 

       190        200        210        220 
QRRLDHDFDD ESDTILEDQM MKLLAKWQQE HTHLPTLYSV AYY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382133 Genomic DNA. Translation: CAG84628.2.
RefSeqXP_456672.2. XM_456672.1.

3D structure databases

ProteinModelPortalQ6BYP7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4959.Q6BYP7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2899647.
KEGGdha:DEHA2A07854g.

Phylogenomic databases

eggNOGCOG5211.
HOGENOMHOG000183445.
KOK15544.
OMAKICTVCA.
OrthoDBEOG7GTTG0.

Family and domain databases

InterProIPR006811. RNA_pol_II_suA.
[Graphical view]
PANTHERPTHR20383. PTHR20383. 1 hit.
PfamPF04722. Ssu72. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSSU72_DEBHA
AccessionPrimary (citable) accession number: Q6BYP7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: December 16, 2008
Last modified: April 16, 2014
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families