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Q6BYL2

- Q6BYL2_DEBHA

UniProt

Q6BYL2 - Q6BYL2_DEBHA

Protein

Histone deacetylase

Gene

DEHA2A08712g

Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 2 (04 Nov 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    Ordered Locus Names:DEHA2A08712gImported
    OrganismiDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)Imported
    Taxonomic identifieri284592 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces
    ProteomesiUP000000599: Chromosome A

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi4959.Q6BYL2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6BYL2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000225180.
    KOiK11483.
    OMAiARIWLEM.
    OrthoDBiEOG78M0B2.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    Q6BYL2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSIPANQSPT FTKDKKTQEN TPLYLANSTS KLPNVSYHYN PQVSQYHFGP    50
    HHPMKPFRLM LTDHLVISYK LYEQMDLYTP RRATKEELLE FHAEDYIDFL 100
    QTITPEKTLK MSDQKLAQFN IGDDCPVFDG IYDYSSIYAG ASLDASRKLI 150
    SGMSDIAINW SGGLHHAKKF EPSGFCYVND IVLSIINLLR VHPRVMYIDI 200
    DLHHGDGVQE AFYVTDRVMT VSFHKYNGEF FPGTGSVDET GLGKGKNYAV 250
    NVPLKDGIDD DSYIRLFKSI MEPLITKFQP TCIVQQCGAD SLGYDRLGCF 300
    NLNIRAHGEC VKYIKSFGIP MLVLGGGGYT PRNVSRLWCY ETSVLNDVTL 350
    DHTIPNYLPT HDWFGPDYSL HPQLDGRIDN KNSKKYLESV KQEVLEQLRY 400
    LTYAPSVQMQ EIPPDITGLT EEEEDIIKEL NSMNDDKDVR IMKNIKDEAR 450
    SSEMVN 456
    Length:456
    Mass (Da):51,967
    Last modified:November 4, 2008 - v2
    Checksum:iAA42CC429615F8AE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382133 Genomic DNA. Translation: CAG84663.2.
    RefSeqiXP_456707.2. XM_456707.1.

    Genome annotation databases

    GeneIDi2899758.
    KEGGidha:DEHA2A08712g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382133 Genomic DNA. Translation: CAG84663.2 .
    RefSeqi XP_456707.2. XM_456707.1.

    3D structure databases

    ProteinModelPortali Q6BYL2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4959.Q6BYL2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2899758.
    KEGGi dha:DEHA2A08712g.

    Phylogenomic databases

    HOGENOMi HOG000225180.
    KOi K11483.
    OMAi ARIWLEM.
    OrthoDBi EOG78M0B2.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. "Genome evolution in yeasts."
      Genolevures
      Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.
      , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.
      Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968Imported.

    Entry informationi

    Entry nameiQ6BYL2_DEBHA
    AccessioniPrimary (citable) accession number: Q6BYL2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 16, 2004
    Last sequence update: November 4, 2008
    Last modified: October 1, 2014
    This is version 66 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3