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Q6BUP9 (ARGD_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetylornithine aminotransferase, mitochondrial
Short name=ACOAT
EC=2.6.1.11
Gene names
Name:ARG8
Ordered Locus Names:DEHA2C09042g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Debaryomyces

Protein attributes

Sequence length466 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.

Subcellular location

Mitochondrion matrix By similarity.

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis
   Cellular componentMitochondrion
   DomainTransit peptide
   LigandPyridoxal phosphate
   Molecular functionAminotransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentmitochondrial matrix

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionN2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity

Inferred from electronic annotation. Source: EC

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion Potential
Chain? – 466Acetylornithine aminotransferase, mitochondrialPRO_0000002078

Amino acid modifications

Modified residue3081N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6BUP9 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 7AEE29F6C69BFAC7

FASTA46650,653
        10         20         30         40         50         60 
MLRNIPRSLR KDGGKRIPGL ISRVANQFST TSSLLNKKSI PDAPEDSHTG QYINTITKPF 

        70         80         90        100        110        120 
TVTTYARPNV VMTHGKGSYL YDLENRQYLD FSAGIAVTCL GHSHSKITEI ISDQAATLMH 

       130        140        150        160        170        180 
CSNLYHNLYA GELANKLVTN TINSGGMKEA QRVFLCNSGT EANEAALKFA RKYGKSFSDD 

       190        200        210        220        230        240 
KYEMITFKNS FHGRTMGALS VTPNEKYQKP FAPLVPGVKI AEPNDISSVE KLISKEKTCA 

       250        260        270        280        290        300 
VIIEPIQGEG GVNAIDAEFL VSLKKLCVDN EVVLIYDEIQ CGLGRSGKLW AHCNLPEEAH 

       310        320        330        340        350        360 
PDILTMAKAL GNGFPIGAVM VSDKIEKVLK VGDHGTTYGG NPLGSKIGSY VVDQVSDKEF 

       370        380        390        400        410        420 
LLEVEEKSEK FTKGLSKIAN KHPDHIGEVK GKGLLLGLQL KGNLDVGDVV AKCRENGLLV 

       430        440        450        460 
ISAGMNVLRI VPALNIPNEA IEEGLDVLDK CIDELSKDPK SSFSQS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382135 Genomic DNA. Translation: CAG86141.1.
RefSeqXP_458070.1. XM_458070.1.

3D structure databases

ProteinModelPortalQ6BUP9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6BUP9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2900662.
GenomeReviewsGene locus DEHA2C09042g in contig CR382135_GR.
KEGGdha:DEHA2C09042g.

Phylogenomic databases

eggNOGfuNOG06187.
HOGENOMHBG725944.
OMATTYARPN.
OrthoDBEOG4HMNJM.

Family and domain databases

InterProIPR004636. AcOrn/SuccinylOrn_aminoTrfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 2 hits.
KOK00818.
PANTHERPTHR11986. Aminotrans_3. 1 hit.
PTHR11986:SF19. ArgD_aminotrans. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR00707. ArgD. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARGD_DEBHA
AccessionPrimary (citable) accession number: Q6BUP9
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: August 16, 2004
Last modified: December 14, 2011
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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