Q6BUE3 (PXR1_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein PXR1

Alternative name(s):
PinX1-related protein 1

Gene names

Name:	PXR1
Ordered Locus Names:	DEHA2C11506g

Organism

Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]

Taxonomic identifier

284592 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Debaryomyces › Debaryomyces hansenii › Debaryomyces hansenii var. hansenii

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase By similarity.
Subcellular location	Nucleus › nucleolus By similarity.
Sequence similarities	Belongs to the PINX1 family. Contains 1 G-patch domain.

Ontologies

Keywords
Biological process	Ribosome biogenesis rRNA processing
Cellular component	Nucleus
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	rRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleolus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	2 – 316	315	Protein PXR1		PRO_0000324888
Regions
	Domain	25 – 71	47	G-patch
	Compositional bias	137 – 266	130	Lys-rich

Sequences

	Sequence		Length	Mass (Da)
	Q6BUE3 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 4A9F99A0C3119EE9	FASTA	316	36,976
	10 20 30 40 50 60 MGLAGTKVKQ RFGLDPRNTN WSNDTSRFGH QYLERMGWKP GKGLGLVEHA TTSHVKVSIK 70 80 90 100 110 120 DDNLGLGSKL AKKQKTDEFD SGECSGLDVF QRILGRLNGK EDQINKEIER KRKDNIINGK 130 140 150 160 170 180 WGIQFIKGEV LQSTWDKEAK KLLDKGTTKK RKIDSVDSSE ESTTSSDSKQ HKKKKIKKDR 190 200 210 220 230 240 KEKEEKKTEK ENSEIKKKKK EKKEKKEKKE KKDKNEKKEK KDKNEKKEKK DKNEEKEKKE 250 260 270 280 290 300 KKEKKEKKDK KDKKDKKDKK EKKEVKEVTR DSMLMPKEQL NQQIATRLSV RSKWIKQKRA 310 SVMDAKALNE IFMVTS

References

[1]

"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR382135 Genomic DNA. Translation: CAG86250.1.
RefSeq	XP_458176.1. XM_458176.1.
3D structure databases
HSSP	HSSP built from PDB template 2AP3 based on UniProtKB Q8NX77.
ModBase	Search...
Protein-protein interaction databases
STRING	4959.Q6BUE3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2900241.
KEGG	dha:DEHA2C11506g.
Phylogenomic databases
eggNOG	NOG263032.
HOGENOM	HOG000048630.
KO	K11135.
OMA	YSDSHKK.
OrthoDB	EOG4RFQ32.
Family and domain databases
InterPro	IPR000467. G_patch_dom. [Graphical view]
Pfam	PF01585. G-patch. 1 hit. [Graphical view]
SMART	SM00443. G_patch. 1 hit. [Graphical view]
PROSITE	PS50174. G_PATCH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PXR1_DEBHA

Accession

Primary (citable) accession number: Q6BUE3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	August 16, 2004
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program