SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6BTV5

- SIL1_DEBHA

UniProt

Q6BTV5 - SIL1_DEBHA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Nucleotide exchange factor SIL1

Gene
SIL1, DEHA2C15664g
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 By similarity.

GO - Biological processi

  1. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleotide exchange factor SIL1
Gene namesi
Name:SIL1
Ordered Locus Names:DEHA2C15664g
OrganismiDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Taxonomic identifieri284592 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces
ProteomesiUP000000599: Chromosome C

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum lumen Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222 Reviewed predictionAdd
BLAST
Chaini23 – 427405Nucleotide exchange factor SIL1PRO_0000223362Add
BLAST

Interactioni

Subunit structurei

Interacts with KAR2 By similarity.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi424 – 4274Prevents secretion from ER Reviewed prediction

Sequence similaritiesi

Belongs to the SIL1 family.

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG284817.
HOGENOMiHOG000094513.
KOiK14001.
OMAiSHDIEFG.
OrthoDBiEOG7V1G2Q.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6BTV5-1 [UniParc]FASTAAdd to Basket

« Hide

MKLSKGVLSS ILLTLLIKPI ESSIVNTDGE LICAPNNPTD CYPKIFEPTT    50
EWQTIREGQD IPAGLHVRLN MENLAREAKI LDPSEETEGS SELMVNAEQN 100
NDNGDNSHQM TNEDQANEIQ QKIKEFKQTQ GKSKVSTVDL NDFQSSVDEV 150
QHYREGGDAN RLSTALDTLI DLSHDIEFGV KLTQDSSVFR SLVDVSKSVQ 200
DEDLQEKVYR IMGSSLRNNP DAVNHVLKNQ DATFVECLFD KLDTDASDVI 250
KKRILGIIHA LTQNSHFNAK YFNSNNANSA VDSLISVFPS LESQSQTRLM 300
NILEDLKLLG GANSNEKRAI EESADPKSQY SHFLQHSLAD SGVASEDQFK 350
LYFNKLSEVH SQDKSLKPSK AFMEWLSKEA ELRSKGNKER DSSYTEEDRQ 400
FDQDLLRARH VVFGNPMGLR KALADEL 427
Length:427
Mass (Da):47,943
Last modified:December 16, 2008 - v2
Checksum:iACCDA7231D0A3B3B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382135 Genomic DNA. Translation: CAR65586.1.
RefSeqiXP_002770223.1. XM_002770177.1.

Genome annotation databases

GeneIDi8998396.
KEGGidha:DEHA2C15664g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR382135 Genomic DNA. Translation: CAR65586.1 .
RefSeqi XP_002770223.1. XM_002770177.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8998396.
KEGGi dha:DEHA2C15664g.

Phylogenomic databases

eggNOGi NOG284817.
HOGENOMi HOG000094513.
KOi K14001.
OMAi SHDIEFG.
OrthoDBi EOG7V1G2Q.

Family and domain databases

InterProi IPR016024. ARM-type_fold.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
PROSITEi PS00014. ER_TARGET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Entry informationi

Entry nameiSIL1_DEBHA
AccessioniPrimary (citable) accession number: Q6BTV5
Secondary accession number(s): B5RTC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: December 16, 2008
Last modified: November 13, 2013
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3