Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6BTV5

- SIL1_DEBHA

UniProt

Q6BTV5 - SIL1_DEBHA

Protein

Nucleotide exchange factor SIL1

Gene

SIL1

Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 2 (16 Dec 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 By similarity.By similarity

    GO - Biological processi

    1. protein transport Source: UniProtKB-KW

    Keywords - Biological processi

    Protein transport, Translocation, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nucleotide exchange factor SIL1
    Gene namesi
    Name:SIL1
    Ordered Locus Names:DEHA2C15664g
    OrganismiDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
    Taxonomic identifieri284592 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces
    ProteomesiUP000000599: Chromosome C

    Subcellular locationi

    Endoplasmic reticulum lumen PROSITE-ProRule annotation

    GO - Cellular componenti

    1. endoplasmic reticulum lumen Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222Sequence AnalysisAdd
    BLAST
    Chaini23 – 427405Nucleotide exchange factor SIL1PRO_0000223362Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with KAR2.By similarity

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi424 – 4274Prevents secretion from ERPROSITE-ProRule annotation

    Sequence similaritiesi

    Belongs to the SIL1 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG284817.
    HOGENOMiHOG000094513.
    KOiK14001.
    OMAiSHDIEFG.
    OrthoDBiEOG7V1G2Q.

    Family and domain databases

    InterProiIPR016024. ARM-type_fold.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.
    PROSITEiPS00014. ER_TARGET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6BTV5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLSKGVLSS ILLTLLIKPI ESSIVNTDGE LICAPNNPTD CYPKIFEPTT    50
    EWQTIREGQD IPAGLHVRLN MENLAREAKI LDPSEETEGS SELMVNAEQN 100
    NDNGDNSHQM TNEDQANEIQ QKIKEFKQTQ GKSKVSTVDL NDFQSSVDEV 150
    QHYREGGDAN RLSTALDTLI DLSHDIEFGV KLTQDSSVFR SLVDVSKSVQ 200
    DEDLQEKVYR IMGSSLRNNP DAVNHVLKNQ DATFVECLFD KLDTDASDVI 250
    KKRILGIIHA LTQNSHFNAK YFNSNNANSA VDSLISVFPS LESQSQTRLM 300
    NILEDLKLLG GANSNEKRAI EESADPKSQY SHFLQHSLAD SGVASEDQFK 350
    LYFNKLSEVH SQDKSLKPSK AFMEWLSKEA ELRSKGNKER DSSYTEEDRQ 400
    FDQDLLRARH VVFGNPMGLR KALADEL 427
    Length:427
    Mass (Da):47,943
    Last modified:December 16, 2008 - v2
    Checksum:iACCDA7231D0A3B3B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382135 Genomic DNA. Translation: CAR65586.1.
    RefSeqiXP_002770223.1. XM_002770177.1.

    Genome annotation databases

    GeneIDi8998396.
    KEGGidha:DEHA2C15664g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR382135 Genomic DNA. Translation: CAR65586.1 .
    RefSeqi XP_002770223.1. XM_002770177.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8998396.
    KEGGi dha:DEHA2C15664g.

    Phylogenomic databases

    eggNOGi NOG284817.
    HOGENOMi HOG000094513.
    KOi K14001.
    OMAi SHDIEFG.
    OrthoDBi EOG7V1G2Q.

    Family and domain databases

    InterProi IPR016024. ARM-type_fold.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    PROSITEi PS00014. ER_TARGET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Entry informationi

    Entry nameiSIL1_DEBHA
    AccessioniPrimary (citable) accession number: Q6BTV5
    Secondary accession number(s): B5RTC4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 21, 2006
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 61 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3