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Q6BTV5 (SIL1_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 By similarity.

Subunit structure

Interacts with KAR2 By similarity.

Subcellular location

Endoplasmic reticulum lumen By similarity.

Sequence similarities

Belongs to the SIL1 family.

Ontologies

Keywords
   Biological processProtein transport
Translocation
Transport
   Cellular componentEndoplasmic reticulum
   DomainSignal
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentendoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 427405Nucleotide exchange factor SIL1
PRO_0000223362

Regions

Motif424 – 4274Prevents secretion from ER Potential

Sequences

Sequence LengthMass (Da)Tools
Q6BTV5 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: ACCDA7231D0A3B3B

FASTA42747,943
        10         20         30         40         50         60 
MKLSKGVLSS ILLTLLIKPI ESSIVNTDGE LICAPNNPTD CYPKIFEPTT EWQTIREGQD 

        70         80         90        100        110        120 
IPAGLHVRLN MENLAREAKI LDPSEETEGS SELMVNAEQN NDNGDNSHQM TNEDQANEIQ 

       130        140        150        160        170        180 
QKIKEFKQTQ GKSKVSTVDL NDFQSSVDEV QHYREGGDAN RLSTALDTLI DLSHDIEFGV 

       190        200        210        220        230        240 
KLTQDSSVFR SLVDVSKSVQ DEDLQEKVYR IMGSSLRNNP DAVNHVLKNQ DATFVECLFD 

       250        260        270        280        290        300 
KLDTDASDVI KKRILGIIHA LTQNSHFNAK YFNSNNANSA VDSLISVFPS LESQSQTRLM 

       310        320        330        340        350        360 
NILEDLKLLG GANSNEKRAI EESADPKSQY SHFLQHSLAD SGVASEDQFK LYFNKLSEVH 

       370        380        390        400        410        420 
SQDKSLKPSK AFMEWLSKEA ELRSKGNKER DSSYTEEDRQ FDQDLLRARH VVFGNPMGLR 


KALADEL 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382135 Genomic DNA. Translation: CAR65586.1.
RefSeqXP_002770223.1. XM_002770177.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8998396.
KEGGdha:DEHA2C15664g.

Phylogenomic databases

eggNOGNOG284817.
HOGENOMHOG000094513.
KOK14001.
OMASHDIEFG.
OrthoDBEOG7V1G2Q.

Family and domain databases

InterProIPR016024. ARM-type_fold.
[Graphical view]
SUPFAMSSF48371. SSF48371. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSIL1_DEBHA
AccessionPrimary (citable) accession number: Q6BTV5
Secondary accession number(s): B5RTC4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: December 16, 2008
Last modified: November 13, 2013
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families