Reviewed, UniProtKB/Swiss-Prot Q6BST1 (ALG13_DEBHA)

Names and origin

Protein names

Recommended name:
    UDP-N-acetylglucosamine transferase subunit ALG13
    EC=2.4.1.141
Alternative name(s):
    Asparagine-linked glycosylation protein 13

Gene names

Name:	ALG13
Ordered Locus Names:	DEHA2D06468g

Organism

Debaryomyces hansenii (Yeast) (Torulaspora hansenii) [Complete proteome]

Taxonomic identifier

4959 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Debaryomyces

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway By similarity.
Catalytic activity	UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.
Subunit structure	Heterodimer with ALG14 to form a functional enzyme By similarity.
Subcellular location	Endoplasmic reticulum By similarity.
Sequence similarities	Belongs to the glycosyltransferase 28 family.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro lipid glycosylation Inferred from electronic annotation. Source: InterPro
Cellular component	endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 212	212	UDP-N-acetylglucosamine transferase subunit ALG13		PRO_0000215601

Sequences

	Sequence		Length	Mass (Da)
	Q6BST1-1 [UniParc]. Last modified December 16, 2008. Version 2. Checksum: 1A1E46A9AB4CA7B0	FASTA	212	23,838
	10 20 30 40 50 60 MTSVLFTSGA TVTFRELIEV ITSYDFIVET IIGNGITRMI VQYGNEIETG TQKHVSEEFY 70 80 90 100 110 120 RQCVEDKELK QSLQLEVVSG SQNDSNVVTY RSNKYRGFEM VVFPFSNDIG SFISESDVVI 130 140 150 160 170 180 SHAGTGSIID TLRLEKPLIV VTNDKLMNKH QEEVADELVK LGCCRKMTIE DMKSSQLKDC 190 200 210 ISEILSGPET FNKLPECSTT EVEGIIYHEL VK

References

[1]

"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 36239 / CBS 767 / IFO 0083 / IGC 2968 / JCM 1990.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR382136 Genomic DNA. Translation: CAG86883.2.
RefSeq	XP_458739.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q6BST1.
Genome annotation databases
GeneID	2900986.
GenomeReviews	Gene locus DEHA2D06468g in contig CR382136_GR.
KEGG	dha:DEHA0D07128g.
Enzyme and pathway databases
BRENDA	2.4.1.141. 74267.
Family and domain databases
InterPro	IPR007235. Glyco_trans_28_C. [Graphical view]
Pfam	PF04101. Glyco_tran_28_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALG13_DEBHA

Accession

Primary (citable) accession number: Q6BST1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
Last sequence update:	December 16, 2008
Last modified:	September 22, 2009
This is version 35 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)