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Q6BRD5 (ACOX_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acyl-coenzyme A oxidase

Short name=Acyl-CoA oxidase
EC=1.3.3.6
Gene names
Name:POX1
Ordered Locus Names:DEHA2D17248g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces

Protein attributes

Sequence length706 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2.

Cofactor

FAD By similarity.

Pathway

Lipid metabolism; peroxisomal fatty acid beta-oxidation.

Subcellular location

Peroxisome By similarity.

Sequence similarities

Belongs to the acyl-CoA oxidase family.

Ontologies

Keywords
   Biological processFatty acid metabolism
Lipid metabolism
   Cellular componentPeroxisome
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processfatty acid beta-oxidation using acyl-CoA oxidase

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentperoxisome

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacyl-CoA dehydrogenase activity

Inferred from electronic annotation. Source: InterPro

acyl-CoA oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 706706Acyl-coenzyme A oxidase
PRO_0000204698

Sequences

Sequence LengthMass (Da)Tools
Q6BRD5 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: D3B95C9C5ADE2F62

FASTA70678,487
        10         20         30         40         50         60 
MVSATNTVNS GVPPNPAASI QAERAASKFD PKEMHYFLEG GEERAEKFKQ MMQQMERDPI 

        70         80         90        100        110        120 
LSANFQYYDL TKDQQRELTA LRIDRLTRYI ENESFDDFNK RMSLMGVFDP QLSTRLGINL 

       130        140        150        160        170        180 
GLFVSCLKGN GTAEQVKYWA MDKSAVYMRG IYGCFGMTEL AHGSNVAGLE TTATFDDEND 

       190        200        210        220        230        240 
EFIINTPHIG ATKWWIGGAA HSATHCSVYA RLIVGGQDYG VKTFVVPLRD SNHDTMPGVT 

       250        260        270        280        290        300 
VGDIGAKMGR DGIDNGWIQF SNVRIPRYFM LQKFCKVSSE GDVQLPPLEQ LSYSALLGGR 

       310        320        330        340        350        360 
VMMVLDSFRV SARFSTVALR YAIGRRQFKA GSASDDKNAL ECQLLDYPLH QRRLLPYLAL 

       370        380        390        400        410        420 
SYIISASAVK IETTIESTLE NLDKAVEADD MGAIMKSIDS MKSLFVDSGS LKSTCTWLAA 

       430        440        450        460        470        480 
EVIDQCRQAC GGHGYSAYSG FGKAYNDWVV MCTWEGDNNV LAMSVGKQII KHILGVLDGK 

       490        500        510        520        530        540 
KVKGSADFLN NTEQYLNEEP VLRSVDDLKD LKKVLLAIEV AIIRVAYQAS QTLKENKGDF 

       550        560        570        580        590        600 
DTVGAEMVTL SKLNAHHFML SEFLDRMDSF ESKQLVPYLE SVAKLYSATI VLEKFAGDFL 

       610        620        630        640        650        660 
AQGVFPPKLN GELNSKHIPE LCKEIRPNVI ALTDSFQQSD MMINSAIGSY DGNIYENYFG 

       670        680        690        700 
VVKANNPPSK TKAPYSGALE AMLNRPSKEE RERFEKSTET AKILSK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR382136 Genomic DNA. Translation: CAG87407.2.
RefSeqXP_459235.2. XM_459235.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4959.Q6BRD5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2901799.
KEGGdha:DEHA2D17248g.

Phylogenomic databases

eggNOGCOG1960.
KOK00232.
OMAYDGDIYE.
OrthoDBEOG7P02SG.

Enzyme and pathway databases

UniPathwayUPA00661.

Family and domain databases

Gene3D1.10.540.10. 1 hit.
2.40.110.10. 1 hit.
InterProIPR029320. Acyl-CoA_ox_N.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR012258. Acyl-CoA_oxidase.
IPR002655. Acyl-CoA_oxidase_C.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
[Graphical view]
PfamPF01756. ACOX. 1 hit.
PF00441. Acyl-CoA_dh_1. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF14749. Acyl-CoA_ox_N. 1 hit.
[Graphical view]
PIRSFPIRSF000168. Acyl-CoA_oxidase. 1 hit.
SUPFAMSSF47203. SSF47203. 2 hits.
SSF56645. SSF56645. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACOX_DEBHA
AccessionPrimary (citable) accession number: Q6BRD5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: December 16, 2008
Last modified: June 11, 2014
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways