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Protein

Transcription factor IWS1

Gene

IWS1

Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor IWS1
Gene namesi
Name:IWS1
Ordered Locus Names:DEHA2E08360g
OrganismiDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Taxonomic identifieri284592 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces
Proteomesi
  • UP000000599 Componenti: Chromosome E

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000833581 – 404Transcription factor IWS1Add BLAST404

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini212 – 289TFIIS N-terminalPROSITE-ProRule annotationAdd BLAST78

Sequence similaritiesi

Belongs to the IWS1 family.Curated
Contains 1 TFIIS N-terminal domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000001004.
InParanoidiQ6BQ49.
KOiK17498.
OMAiRPILNKS.
OrthoDBiEOG092C3BAH.

Family and domain databases

InterProiIPR017923. TFIIS_N.
[Graphical view]
PfamiPF08711. Med26. 1 hit.
[Graphical view]
PROSITEiPS51319. TFIIS_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6BQ49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDKEGETAL YNDREEEARQ FFSDSAEPQS QGGSNELAVN ENEDNNNDEV
60 70 80 90 100
EDDADENIYS IQAHKITGDE ENNREVTMKK NVRKAKKYDE FKNERDEQGF
110 120 130 140 150
VPMGENPEYG GMDYSNEDPQ ARKRRLLEEK MESAIKSKTS RRRRADEDDL
160 170 180 190 200
ERMQDDRIDF LKDQMIKAAN LDVEKNSQGQ IATEKLKLLN EVVDILSKAD
210 220 230 240 250
LAISILDNNL LEAVRLWLEP LPDASMPAYQ IQKELIHSLT VLPIKTDHLI
260 270 280 290 300
ASGIGKVLVY YQRSKRTEAN LKKVVDRLIG DWTRPILNKS DSYKDRTIQF
310 320 330 340 350
NEYNKNRFTN QLSSARRSKP KEAKSLYEES AERRKRAAIP AARTTAYKIA
360 370 380 390 400
PKVDPSLLRR QQLNSNGNND ERFKRINQKL TSMNFKKKSS KKSGPSIEGR

NLTI
Length:404
Mass (Da):46,512
Last modified:December 16, 2008 - v2
Checksum:i527B9CFAEC988A61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382137 Genomic DNA. Translation: CAG87905.2.
RefSeqiXP_459671.2. XM_459671.1.

Genome annotation databases

EnsemblFungiiCAG87905; CAG87905; DEHA2E08360g.
GeneIDi2902270.
KEGGidha:DEHA2E08360g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382137 Genomic DNA. Translation: CAG87905.2.
RefSeqiXP_459671.2. XM_459671.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG87905; CAG87905; DEHA2E08360g.
GeneIDi2902270.
KEGGidha:DEHA2E08360g.

Phylogenomic databases

HOGENOMiHOG000001004.
InParanoidiQ6BQ49.
KOiK17498.
OMAiRPILNKS.
OrthoDBiEOG092C3BAH.

Family and domain databases

InterProiIPR017923. TFIIS_N.
[Graphical view]
PfamiPF08711. Med26. 1 hit.
[Graphical view]
PROSITEiPS51319. TFIIS_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIWS1_DEBHA
AccessioniPrimary (citable) accession number: Q6BQ49
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 16, 2008
Last modified: September 7, 2016
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.