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Q6BND2 (CET1_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
mRNA-capping enzyme subunit beta
EC=3.1.3.33
Alternative name(s):
Polynucleotide 5'-triphosphatase
mRNA 5'-triphosphatase
Short name=TPase
Gene names
Name:CET1
Ordered Locus Names:DEHA2E22726g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Debaryomyces

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end By similarity.

Catalytic activity

A 5'-phosphopolynucleotide + H2O = a polynucleotide + phosphate.

Cofactor

Divalent ions By similarity.

Subunit structure

The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an RNA 5'-triphosphatase By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the fungal TPase family.

Ontologies

Keywords
   Biological processmRNA capping
mRNA processing
   Cellular componentNucleus
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processmRNA capping

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionpolynucleotide 5'-phosphatase activity

Inferred from electronic annotation. Source: EC

transferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476mRNA-capping enzyme subunit beta
PRO_0000210115

Sequences

Sequence LengthMass (Da)Tools
Q6BND2 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: 8FB395B1947EA08A

FASTA47654,622
        10         20         30         40         50         60 
MNVGSILNDE PSPSKKTTND DSGDSVRPDM STYQRHSLVN LLNDPAPNNE LKTKETKKDW 

        70         80         90        100        110        120 
SEDEHSNFRV PVTEPNQQLS PVLRRSSIAD ITNEKDVDIS SSTEHPIEQD KSEKDEDELT 

       130        140        150        160        170        180 
RISKLKSTNK PRRYTEPPIW AQEWIPTSYQ GTANGTPVVN AQESSLSSKR VFDRSSTVNV 

       190        200        210        220        230        240 
DLECSITGVI PPPSVTRTIA EWIYANFTEI PDDQRKYVEL ELKFGTIIDK RAGHRIDINV 

       250        260        270        280        290        300 
STECIFTDNS NTYFDMGVHE VGWNDMCKFL DDLEKSYQDE LRRSPQANSN SPKRKFNILE 

       310        320        330        340        350        360 
SDITDNFYQI TSRNEQPKSI RISKDNLLDP PRYTAINKQR LSSLFIHNPS SMYDLRLSLS 

       370        380        390        400        410        420 
YENPIADNNI DGIIKKNQPT LTRIKKRNSW THRPTVTRFD MTRVLSPRES KNKSGKKIVE 

       430        440        450        460        470 
QDQSFEVELE VDTLELFNGF DKFKSGADSI RFEELVEIFV NNARCLNNRV TKLANK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382137 Genomic DNA. Translation: CAG88572.2.
RefSeqXP_460288.2. XM_460288.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2903003.
GenomeReviewsGene locus DEHA2E22726g in contig CR382137_GR.
KEGGdha:DEHA2E22726g.

Phylogenomic databases

eggNOGfuNOG08284.
HOGENOMHBG397875.
OMAVEITHEI.
OrthoDBEOG4N605N.

Family and domain databases

InterProIPR023577. CYTH-like_domain.
IPR004206. mRNA_capping_enz_bsu_dom.
[Graphical view]
Gene3DG3DSA:3.20.100.10. mRNA_capping_enz_bsu. 1 hit.
KOK01098.
PfamPF02940. mRNA_triPase. 1 hit.
[Graphical view]
SUPFAMSSF55154. mRNA_capping_enz_bsu. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCET1_DEBHA
AccessionPrimary (citable) accession number: Q6BND2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: December 16, 2008
Last modified: November 16, 2011
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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