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Reviewed, UniProtKB/Swiss-Prot Q6BMH4 (MCES_DEBHA)

Last modified June 16, 2009. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    mRNA cap guanine-N7 methyltransferase
    EC=2.1.1.56
Alternative name(s):
    mRNA (guanine-N(7)-)-methyltransferase
    mRNA cap methyltransferase
Gene names
Name: ABD1
Ordered Locus Names: DEHA2F05434g
OrganismDebaryomyces hansenii (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier4959 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeDebaryomyces

Protein attributes

Sequence length524 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Responsible for methylating the 5'-cap structure of mRNAs By similarity.

Catalytic activity

S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the mRNA cap methyltransferase family.

Ontologies

Keywords
   Biological processmRNA capping
mRNA processing
   Cellular componentNucleus
   LigandRNA-binding
S-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processmRNA capping

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

mRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 524524mRNA cap guanine-N7 methyltransferase
PRO_0000303908

Sequences

Sequence LengthMass (Da)Tools
Q6BMH4-1 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: F062DD77414E822E

FASTA52459,331
        10         20         30         40         50         60 
MSDKEAGVAS SLGSNSPINK DEVDVKNTEE HSKQESKSDI NKPPLKKIKA DDGIDISDSF 

        70         80         90        100        110        120 
SRRENKGNNK VISSVYNDEN KKTPAWMKSK TTDKYDKYGS RSTPIATPTA PVNNPDERYS 

       130        140        150        160        170        180 
KYMTNSVNSN DRVRRPPTET TSSQYDKKRA HDEAEDDVVA PYSNLAVANP SSNLYQTFQS 

       190        200        210        220        230        240 
HINNREGKDI NSIVRSHYNQ RTQQSKFQGS RTKSPIYKLR NFNNAIKYIL LGNWVKPNPD 

       250        260        270        280        290        300 
SNRPTVILDL CCGKGGDLNK CEFVSVDQYI GIDISDASIK EAFSRYSRNK ARFIPQTAES 

       310        320        330        340        350        360 
KKERDTRRYN FEACFATGDC FSSSIPEILE PNFPGIIDGL FPVDCVSLQF AMHYAFETEE 

       370        380        390        400        410        420 
KVHQLLTNVT KSLRAGGTLI GTIPSSDFIR DKIVNRAFID QENRKFGNDL YSVTFHKDPP 

       430        440        450        460        470        480 
DEGVFRPPFG NGYNYSLKDA IDDVPEYVVP FEVFRGLCEE YGLVLKYKKN FIDIFNQEIP 

       490        500        510        520 
KYFSKLNKNL IEGMKRSDGK YGAEGLEKEA VGFYIGFVFE KLGN 

« Hide

Cross-references

Sequence databases

CR382138 Genomic DNA. Translation: CAG88922.2.
RefSeqXP_460598.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2903540.
KEGGdha:DEHA0F05940g.

Phylogenomic databases

HOGENOMQ6BMH4.
OMAQ6BMH4. WLEDAID.

Enzyme and pathway databases

BRENDA2.1.1.56. 74267.

Family and domain databases

InterProIPR016899. mRNA_G-N7_MeTrfase.
IPR004971. Pox_MCEL.
[Graphical view]
PfamPF03291. Pox_MCEL. 1 hit.
[Graphical view]
PIRSFPIRSF028762. ABD1. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMCES_DEBHA
AccessionPrimary (citable) accession number: Q6BMH4
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: December 16, 2008
Last modified: June 16, 2009
This is version 26 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents