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Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei130 – 1301Phosphocysteine intermediateBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
Ordered Locus Names:DEHA2F09482g
OrganismiDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Taxonomic identifieri284592 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces
ProteomesiUP000000599 Componenti: Chromosome F

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 196196Putative tyrosine-protein phosphatase OCA1PRO_0000333391Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ6BLZ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000188365.
InParanoidiQ6BLZ8.
KOiK18043.
OMAiNAWDPIT.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6BLZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESQSEIEH NNNNSKLTKI SQPPTVRIIP PLNFCPVEKQ LYRSGQPSII
60 70 80 90 100
NQSFLQDLNL KTILWLASEE PQEDFLDYCS MNNIAVEFVG LMNEYSYQNV
110 120 130 140 150
NPWDALSEDT IKKALELICN KENYPLLVCC GMGRHRTGTV IGCLRRLQGW
160 170 180 190
NLASVSEEYR RFTGSRGGRI MVELLIESFD INSVQIDPTK MPGWLT
Length:196
Mass (Da):22,378
Last modified:August 16, 2004 - v1
Checksum:iA1DD3F03B7601FEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382138 Genomic DNA. Translation: CAG89114.1.
RefSeqiXP_460773.1. XM_460773.1.

Genome annotation databases

GeneIDi2903615.
KEGGidha:DEHA2F09482g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR382138 Genomic DNA. Translation: CAG89114.1.
RefSeqiXP_460773.1. XM_460773.1.

3D structure databases

ProteinModelPortaliQ6BLZ8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2903615.
KEGGidha:DEHA2F09482g.

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000188365.
InParanoidiQ6BLZ8.
KOiK18043.
OMAiNAWDPIT.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiOCA1_DEBHA
AccessioniPrimary (citable) accession number: Q6BLZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 16, 2004
Last modified: June 24, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.