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Reviewed, UniProtKB/Swiss-Prot Q6BKY9 (CCPR_DEBHA)

Last modified January 19, 2010. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Cytochrome c peroxidase, mitochondrial
      Short name=CCP
    EC=1.11.1.5
Gene names
Name: CCP1
Ordered Locus Names: DEHA2F17754g
OrganismDebaryomyces hansenii (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier4959 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Debaryomyces

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Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.

Catalytic activity

2 ferrocytochrome c + H2O2 = 2 ferricytochrome c + 2 H2O.

Cofactor

Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.

Subunit structure

Forms a one-to-one complex with cytochrome c By similarity.

Subcellular location

Mitochondrion Probable.

Sequence similarities

Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.

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Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

response to oxidative stress

Inferred from electronic annotation. Source: InterPro

   Cellular componentmitochondrion

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncytochrome-c peroxidase activity

Inferred from electronic annotation. Source: EC

heme binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion Potential
Chain? – 360Cytochrome c peroxidase, mitochondrialPRO_0000045291

Sites

Active site1181Proton acceptor By similarity
Active site2581Tryptophan radical intermediate By similarity
Metal binding2421Iron (heme axial ligand)
Site1141Transition state stabilizer By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q6BKY9-1 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 98033D6DF83F33C0

FASTA36040,439
        10         20         30         40         50         60 
MSTAAFKRQS VPLSKLFQSY GKNNSQSKYG GYFLATLIGS GILATSYFNN NKNGNTPSNN 

        70         80         90        100        110        120 
HKKLLAGSGI VNTAAIPKGK SIKDYQSLYN EIAEKVRDQD DADDGAGRYG LLTRLAWHTS 

       130        140        150        160        170        180 
GTYKKEDNTG GSYGGTMIYK PESTDGENSG LNHGRDFLQE FKDKYSWLSH GDLWTLGGVV 

       190        200        210        220        230        240 
AVQECGGPKI KWRPGRQDIS DKTRVPENGR LPDASKDADY VKGVFGRMGF NERETVCLIG 

       250        260        270        280        290        300 
AHCLGKCHKE NTNYDGPWGP SFNMFTNDFF VRLLQNWHVK KWDGKKQYED DETNSFMMLP 

       310        320        330        340        350        360 
TDMALKEDSS FLKYVKMYAD DEKLFFSDFA KNFSTLLELG VTFPDSIKPT EFKTLDEQDK

« Hide

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382138 Genomic DNA. Translation: CAG89515.1.
RefSeqXP_461132.1.

3D structure databases

SMRQ6BKY9. Positions 70-359.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6BKY9.

Protein family/group databases

PeroxiBase3061. DhCcP02.

Genome annotation databases

GeneID2904292.
GenomeReviewsGene locus DEHA2F17754g in contig CR382138_GR.
KEGGdha:DEHA0F19173g.

Phylogenomic databases

eggNOGfuNOG05104.
HOGENOMHBG597790.
OMAATMRFAP.
OrthoDBEOG92JQ7X.
PhylomeDBQ6BKY9.

Enzyme and pathway databases

BRENDA1.11.1.5. 74267.

Family and domain databases

InterProIPR002207. Asc_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
[Graphical view]
PfamPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSPR00459. ASPEROXIDASE.
PR00458. PEROXIDASE.
PROSITEPS00435. PEROXIDASE_1. False negative.
PS00436. PEROXIDASE_2. False negative.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameCCPR_DEBHA
AccessionPrimary (citable) accession number: Q6BKY9
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: August 16, 2004
Last modified: January 19, 2010
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents