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Q6BKW1 (ACH1_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-CoA hydrolase
EC=3.1.2.1
Alternative name(s):
Acetyl-CoA deacylase
Short name=Acetyl-CoA acylase
Gene names
Name:ACH1
Ordered Locus Names:DEHA2F18744g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Debaryomyces

Protein attributes

Sequence length523 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation By similarity.

Catalytic activity

Acetyl-CoA + H2O = CoA + acetate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the acetyl-CoA hydrolase/transferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processacetyl-CoA metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionacetyl-CoA hydrolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 523523Acetyl-CoA hydrolase
PRO_0000215519

Sequences

Sequence LengthMass (Da)Tools
Q6BKW1 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 9EED942E19750768

FASTA52358,294
        10         20         30         40         50         60 
MSSILKQRVR YAPYLQKLRT AEQCVELFKH GQYLGWSGFT GVGAPKVVPD AIADHVEKNN 

        70         80         90        100        110        120 
LQGKLGFNLF VGASAGPEEG RWAENDMLLR RSPHQVGKPI AKAINTGKTK FFDKHLSMFP 

       130        140        150        160        170        180 
QDLTYGFYTR EKENDLLDYT IIEATAITED GSIVPGPAVG ASPEMISVSD KIIIEVNTVT 

       190        200        210        220        230        240 
PSFEGLHDID MPVNPPFRQP YPHTTVDYRT GLTAIPVDPS KVVAIVESQT RDKVPPNTPS 

       250        260        270        280        290        300 
DETSRNIANN LLEFFEHEAK LGRLPENLHP LQSGIGNIAN AVVEGLADSK FKNLTVWTEV 

       310        320        330        340        350        360 
LQDSFLDFFE SGSLDFATAT SIRLTEAGFD KFYENWDTYS KKLCLRSQVV SNSPEIIRRL 

       370        380        390        400        410        420 
GTIAMNTPVE VDIYAHANST NVMGSRMLNG LGGSADFLRN SKLSVMHTPS ARPSKTDKTG 

       430        440        450        460        470        480 
VSCIVPFATH VDQTEHDLDI VVTDQGLADL RGLSPKERAR EIITKTSHPD YRDQLTDYLD 

       490        500        510        520 
RATFYAEKSK CLHEPHILQD AFKMHLNFQE NGTMKLDSWD KKF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382138 Genomic DNA. Translation: CAG89543.1.
RefSeqXP_461160.1. XM_461160.1.

3D structure databases

ProteinModelPortalQ6BKW1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6BKW1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2903722.
GenomeReviewsGene locus DEHA2F18744g in contig CR382138_GR.
KEGGdha:DEHA2F18744g.

Phylogenomic databases

eggNOGfuNOG04759.
HOGENOMHBG289696.
OMAEVSNHPE.
OrthoDBEOG4DBXNW.

Family and domain databases

InterProIPR003702. ActCoA_hydro.
IPR017821. Succinate_CoA_transferase.
[Graphical view]
KOK01067.
PANTHERPTHR21432. ActCoA_hydro. 1 hit.
PTHR21432:SF10. PTHR21432:SF10. 1 hit.
PfamPF02550. AcetylCoA_hydro. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACH1_DEBHA
AccessionPrimary (citable) accession number: Q6BKW1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: August 16, 2004
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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