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Q6BKG0 (PPN1_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Endopolyphosphatase
EC=3.6.1.10
Gene names
Name:PPN1
Ordered Locus Names:DEHA2F22264g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Debaryomyces

Protein attributes

Sequence length713 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of inorganic polyphosphate (poly P) chains of many hundreds of phosphate residues into shorter lengths By similarity.

Catalytic activity

Polyphosphate + n H2O = (n+1) oligophosphate.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein.

Post-translational modification

Processing by proteases in the vacuole may be required for activation By similarity.

Ontologies

Keywords
   Cellular componentMembrane
Vacuole
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

vacuolar membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionendopolyphosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 713713Endopolyphosphatase
PRO_0000058546

Regions

Topological domain1 – 1919Cytoplasmic Potential
Transmembrane20 – 4021Helical; Signal-anchor for type II membrane protein; Potential
Topological domain41 – 713673Vacuolar Potential
Compositional bias395 – 41521Asp-rich
Compositional bias638 – 66023Lys-rich

Amino acid modifications

Glycosylation5071N-linked (GlcNAc...) Potential
Glycosylation6451N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q6BKG0 [UniParc].

Last modified December 16, 2008. Version 3.
Checksum: 1DD7BA09E78B4897

FASTA71381,885
        10         20         30         40         50         60 
MSVLIDEKSH RSSGSTRSRI VVTVVGVLLM VSGLAVMLGH QSGSANEALG MEYEKPSVEV 

        70         80         90        100        110        120 
LDLEATEVEQ LTKLGLSPKP KLKIVKGGDE QVLHGRFLHI TDMHPDKYYK TGADVGSLCH 

       130        140        150        160        170        180 
SGKGSAGKYG DAVLGCDSPM VLMEDTLKWV KENLKDKIDF VVWTGDNVRH DNDRRYPRTE 

       190        200        210        220        230        240 
SNIFDMNQRV SELMYETFKE ENPRGGRPRQ LKIPLVPSLG NNDVFPHNLF SPGPTLQTRE 

       250        260        270        280        290        300 
LFKIWHDFVP AAQLHIFNRG AYFFKEIIPN ELAVLSINTL YLFQSNPLVD NCDRKKDPGH 

       310        320        330        340        350        360 
KLFEWLGYTL KEMRARNMKV WLSGHVPPNE KNYDISCLRK YIVWMHEYRD VIIGGLYGHM 

       370        380        390        400        410        420 
NIDHFIPLDS KEAYKSIKNK FGKLGFDYEL SFENDLYVSD DDDNSDSDSD DDDEDTSLEE 

       430        440        450        460        470        480 
SYSNFNSPIL KDGFEDSVNF KNMDDIRIQG GVPNGKVGYM ENVRKEYYAN VKGKKKSGYV 

       490        500        510        520        530        540 
SERYSIAHVT ASVVPTFNSG LRVWEYNITG LQNLLTSDNQ PRFAPWNEFF EGLEKLMETQ 

       550        560        570        580        590        600 
VEADYDDEFI TFGQQVEIFK NDNTFPPKMP KSKSLGPAYI PQAFTPERYV QYYADLANIN 

       610        620        630        640        650        660 
RGEKEFSYEF EYATDDKVYD MDSLTVDDWI SLARRLGKPV KEKKNKSNKK SKKKKKNKDK 

       670        680        690        700        710 
RLLENSEPLK QDGSKDSRLE QDRVQQSARL ENLWQHYLKY SFVSSEYENM GMG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382138 Genomic DNA. Translation: CAG89712.2.
RefSeqXP_461311.2. XM_461311.2.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ6BKG0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2904257.
GenomeReviewsGene locus DEHA2F22264g in contig CR382138_GR.
KEGGdha:DEHA2F22264g.

Phylogenomic databases

eggNOGfuNOG05066.
HOGENOMHBG397833.
OMAGGLYGHM.
OrthoDBEOG4TMV9Q.

Family and domain databases

InterProIPR012358. EndopolyPtase_N1.
IPR004843. Metallo_PEstase_dom.
[Graphical view]
KOK06018.
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFPIRSF027093. EndopolyPtase_N1. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPN1_DEBHA
AccessionPrimary (citable) accession number: Q6BKG0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: December 16, 2008
Last modified: November 16, 2011
This is version 52 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program
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