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Q6BJF4 (NMT_DEBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycylpeptide N-tetradecanoyltransferase
EC=2.3.1.97
Alternative name(s):
Myristoyl-CoA:protein N-myristoyltransferase
Short name=NMT
Peptide N-myristoyltransferase
Gene names
Name:NMT1
Ordered Locus Names:DEHA2G02816g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Debaryomyces

Protein attributes

Sequence length451 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins By similarity.

Catalytic activity

Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the NMT family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processN-terminal protein myristoylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionglycylpeptide N-tetradecanoyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 451451Glycylpeptide N-tetradecanoyltransferase
PRO_0000064240

Regions

Region37 – 404Myristoyl CoA-binding By similarity
Region169 – 20537Myristoyl CoA-binding By similarity

Sites

Active site4511Proton acceptor; via carboxylate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6BJF4 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: C386F6A5B5E929E4

FASTA45151,853
        10         20         30         40         50         60 
MSEEDKKDPP KSIEDLMKLL SMGESLTEPQ QKQMKDYKFW KTQPVPSFDE KIDSEGPIDQ 

        70         80         90        100        110        120 
TKTPDDIPDT PLPLLNEFEW STVDLEKTDQ LDEVYKLLYE NYVEDQDATF RFKYSHEFFN 

       130        140        150        160        170        180 
WALKPPGWRT EWHAGVRVKE TGKLVAFIAA IPITLKLNKS QKVIPSVEIN FLCVHKKLRS 

       190        200        210        220        230        240 
KRLAPVMIKE ITRRVNKYDI WQALYTGGVV LPSPVATCRY THRPINWSKL YDVGFSHLPA 

       250        260        270        280        290        300 
NQTKSGMLAN YALPNTTKTQ GLRSMKIEDL DQVYDLLHKF QEKFDIVQVF EKDELAHWLL 

       310        320        330        340        350        360 
GGKSTDTSSN VIKSYVVENS EGSLTDFFSY YLLPFTVLDN PSHDELGIAY LYYYASDTAF 

       370        380        390        400        410        420 
KNDDESAYKQ RLSSLMSDAL VTSKKYNVDV FNCLSSQDNP YFIKNCKFGS GDGFLNYYLF 

       430        440        450 
NYKTWPITGG IDPQTKELVE DKSSGVGVIL L

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382139 Genomic DNA. Translation: CAG90115.1.
RefSeqXP_461667.1. XM_461667.1.

3D structure databases

ProteinModelPortalQ6BJF4.
SMRQ6BJF4. Positions 55-451.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6BJF4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2904533.
GenomeReviewsGene locus DEHA2G02816g in contig CR382139_GR.
KEGGdha:DEHA2G02816g.

Phylogenomic databases

eggNOGfuNOG07746.
HOGENOMHBG314670.
OMAEHAKGSP.
OrthoDBEOG4V9XZZ.

Family and domain databases

InterProIPR016181. Acyl_CoA_acyltransferase.
IPR000903. MyristoylCoA_TrFase.
IPR022677. MyristoylCoA_TrFase_C.
IPR022678. MyristoylCoA_TrFase_CS.
IPR022676. MyristoylCoA_TrFase_N.
[Graphical view]
Gene3DG3DSA:3.40.630.30. Acyl_CoA_acyltransferase. 2 hits.
KOK00671.
PANTHERPTHR11377. Myristoyl_trans. 1 hit.
PfamPF01233. NMT. 1 hit.
PF02799. NMT_C. 1 hit.
[Graphical view]
PIRSFPIRSF015892. N-myristl_transf. 1 hit.
SUPFAMSSF55729. Acyl_CoA_acyltransferase. 2 hits.
PROSITEPS00975. NMT_1. 1 hit.
PS00976. NMT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNMT_DEBHA
AccessionPrimary (citable) accession number: Q6BJF4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: August 16, 2004
Last modified: December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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