Reviewed, UniProtKB/Swiss-Prot Q6BIB1 (CCPR2_DEBHA)

Names and origin

Protein names

Recommended name:
    Putative heme-binding peroxidase
    EC=1.11.1.-

Gene names

Ordered Locus Names:

DEHA2G12166g

Organism

Debaryomyces hansenii (Yeast) (Torulaspora hansenii) [Complete proteome]

Taxonomic identifier

4959 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Debaryomyces

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.
Cofactor	Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.
Sequence similarities	Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.

Ontologies

Keywords
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to oxidative stress Inferred from electronic annotation. Source: InterPro
Molecular function	heme binding Inferred from electronic annotation. Source: InterPro peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 428	428	Putative heme-binding peroxidase		PRO_0000055586
Sites
	Active site	188	1	Proton acceptor
	Active site	328	1	Tryptophan radical intermediate By similarity
	Metal binding	312	1	Iron (heme axial ligand)
	Site	184	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6BIB1-1 [UniParc]. Last modified December 16, 2008. Version 3. Checksum: 52A290AC7B0A3FA9	FASTA	428	48,399
	10 20 30 40 50 60 MTAIQKPVVA KREAPKAEVN PTVSRSTQTE TIKPTKERTV SVFSPPVFNF AANSFAQSVS 70 80 90 100 110 120 NEYKHASPKR IKLDNSRVQV PSIVKPKQDK PRPPAIVTKP RVINIEFPNK QKSGFKLLIR 130 140 150 160 170 180 PKHEPSIKKQ KQGIEVLSTS NTKRITKSIS VDDVEYVEKV KHAIKQVLPK PDYDDGSLGP 190 200 210 220 230 240 VILRLAWHCC ATYNKFTGNG GSNGSTMRFV PEITDDGNSG LDIARSALEP IKQKFPDITY 250 260 270 280 290 300 SDLWTLAGKI SIQEMGGPKI PWRCGRVDCI DDRYVPPNGR LPFAYKNANH IRETFGRMGF 310 320 330 340 350 360 NDRETVSLLG AHGLGRCHKR FSGWEGKWTE NPTSFSNDFY KVLLDEEWSL GTVPETGKEQ 370 380 390 400 410 420 YYNKDKSLIM LNTDIELIRD PHFLHFVKLY SQHQATFFQD FANAFGKLLE LGIERDSNGN VLPKNEFY

References

[1]

"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 36239 / CBS 767 / IFO 0083 / IGC 2968 / JCM 1990.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR382139 Genomic DNA. Translation: CAG90546.2. Different initiation.
RefSeq	XP_462060.1.
3D structure databases
ModBase	Search...
Protein family/group databases
PeroxiBase	2619. DhCcP01.
Genome annotation databases
GeneID	2904971.
KEGG	dha:DEHA0G12925g.
Phylogenomic databases
HOGENOM	Q6BIB1.
Family and domain databases
InterPro	IPR002207. Asc_perxdse. IPR002016. Haem_peroxidase_pln/fun/bac. IPR019794. Peroxidases_AS. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view]
Pfam	PF00141. peroxidase. 1 hit. [Graphical view]
PRINTS	PR00459. ASPEROXIDASE. PR00458. PEROXIDASE.
PROSITE	PS00435. PEROXIDASE_1. False negative. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CCPR2_DEBHA

Accession

Primary (citable) accession number: Q6BIB1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	December 16, 2008
Last modified:	June 16, 2009
This is version 36 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)