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Q6BHB2 (Q6BHB2_DEBHA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Adenosylhomocysteinase RuleBase RU000548
EC=3.3.1.1 RuleBase RU000548
Gene names
Ordered Locus Names:DEHA2G19910g
OrganismDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) [Complete proteome]
Taxonomic identifier284592 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Debaryomyces

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine. RuleBase RU000548

Cofactor

NAD By similarity. RuleBase RU000548

Pathway

Amino-acid biosynthesis; homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1. RuleBase RU000548

Sequence similarities

Belongs to the adenosylhomocysteinase family. RuleBase RU004166

Ontologies

Keywords
   Biological processOne-carbon metabolism RuleBase RU000548
   LigandNAD RuleBase RU000548
   Molecular functionHydrolase RuleBase RU000548
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processone-carbon metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionadenosylhomocysteinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site581Substrate By similarity PIRSR PIRSR001109-1
Binding site1341Substrate By similarity PIRSR PIRSR001109-1
Binding site1591Substrate By similarity PIRSR PIRSR001109-1
Binding site1891Substrate By similarity PIRSR PIRSR001109-1
Binding site1931Substrate By similarity PIRSR PIRSR001109-1

Sequences

Sequence LengthMass (Da)Tools
Q6BHB2 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: C4C59862249293FB

FASTA44948,801
        10         20         30         40         50         60 
MSAPASNYKV ADISLAAFGR KDIELSENEM PGLMDIRKKY GSSQPLKGAR VAGCLHMTIQ 

        70         80         90        100        110        120 
TAVLIETLVA LGAEVTWSSC NIFSTQDHAA AAIAAAGVPV FAWKGETDEE YEWCIEQQLF 

       130        140        150        160        170        180 
AFKDGKKLNL ILDDGGDLTT LVHKKYPEML DDCYGLSEET TTGVHHLYKM LKEGTLKVPA 

       190        200        210        220        230        240 
INVNDSVTKS KFDNLYGCRE SLIDGIKRAT DVMIAGKVAV VAGFGDVGKG CAMALRGMGA 

       250        260        270        280        290        300 
RVIVTEIDPI NALQAAVSGY QVAPLEEVAS IGQIFVTTTG CRDIITGVHF EQMPEDAIVC 

       310        320        330        340        350        360 
NIGHFDIEID VAWLKANSES VVEIKPQVDR FLMKNGRHVI LLAEGRLVNL GCATGHSSFV 

       370        380        390        400        410        420 
MSCSFSNQVL AQIALFKAED KEFLAKFPEF GKSDKFDIGV HLLPKVLDET VAKCHLDHLG 

       430        440 
AKLTVLSDVQ AEYLGIPKEG PFKADIYKY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR382139 Genomic DNA. Translation: CAG90918.1.
RefSeqXP_462409.1. XM_462409.1.

3D structure databases

ProteinModelPortalQ6BHB2.
SMRQ6BHB2. Positions 8-449.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6BHB2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2905354.
GenomeReviewsGene locus DEHA2G19910g in contig CR382139_GR.
KEGGdha:DEHA2G19910g.

Phylogenomic databases

eggNOGfuNOG06806.
HOGENOMHBG352029.
OMAELFTKTE.
OrthoDBEOG41G6CK.

Family and domain databases

HAMAPMF_00563. AdoHcyase.
[Tree]
InterProIPR000043. Adenosylhomocysteinase.
IPR015878. Ado_hCys_hydrolase_NAD-bd.
IPR020082. S-Ado-L-homoCys_hydrolase_CS.
[Graphical view]
KOK01251.
PANTHERPTHR23420. Ad_hcy_hydrolase. 1 hit.
PfamPF05221. AdoHcyase. 1 hit.
PF00670. AdoHcyase_NAD. 1 hit.
[Graphical view]
PIRSFPIRSF001109. Ad_hcy_hydrolase. 1 hit.
SMARTSM00996. AdoHcyase. 1 hit.
SM00997. AdoHcyase_NAD. 1 hit.
[Graphical view]
TIGRFAMsTIGR00936. AhcY. 1 hit.
PROSITEPS00738. ADOHCYASE_1. 1 hit.
PS00739. ADOHCYASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6BHB2_DEBHA
AccessionPrimary (citable) accession number: Q6BHB2
Entry history
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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