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Q6BET1

- Q6BET1_CAEEL

UniProt

Q6BET1 - Q6BET1_CAEEL

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Protein
Submitted name:

Protein F14B4.2, isoform b

Gene

CELE_F14B4.2

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: RefGenome
  4. mannokinase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. cellular glucose homeostasis Source: RefGenome
  3. glucose 6-phosphate metabolic process Source: GOC
  4. glycolytic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_232743. Glucose transport.
REACT_254189. Regulation of gene expression in beta cells.
REACT_260911. Regulation of Glucokinase by Glucokinase Regulatory Protein.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein F14B4.2, isoform bImported
Gene namesi
ORF Names:CELE_F14B4.2Imported, F14B4.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome I

Organism-specific databases

WormBaseiF14B4.2b; CE36925; WBGene00008780.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: RefGenome
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ6BET1. baseline.

Structurei

3D structure databases

ProteinModelPortaliQ6BET1.
SMRiQ6BET1. Positions 32-485.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
HOGENOMiHOG000162670.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6BET1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAATGKCSKV RPRFEMLKSM SIQNSIDVSN NQMIQEACQR LVLSDQQLRR
60 70 80 90 100
IMQSMEKSME QGLATSTKKV AVKMLPTYVD SVPNGTESGD FLALDLGGTN
110 120 130 140 150
FRVLHIKLQG KETKMTGKIF RVPESIMRGT GEALFDHIAG CMAKFMGEND
160 170 180 190 200
LKDAQKLPLG FTFSFPCEQE GLTKGKLVTW TKGFKASGVE GVDVVTLLHE
210 220 230 240 250
ACHRRKDIDI DVVALLNDTV GTLMACAFQE NSCQIGVIVG TGTNACYMER
260 270 280 290 300
LDRIPKLAGY VDEHGVTPEE MIINTEWGAF GDDGALDFLR TEWDEVVDRE
310 320 330 340 350
SINPGQHLYE KMISGMYMGE CARVVLEDLA KQGLLFGGNS DAISVPHCFP
360 370 380 390 400
TKFVSEIDSD LLEDDDRTFQ KTYQILEDIG VEMITANDCA NVAYVCSLIS
410 420 430 440 450
TRAAHLTAAG IAMLLNRMNK KHVTVGVDGS VYRFHPTYPT LLDAKIGELI
460 470 480 490
VGDIEYKLML SEDGSGRGAA LVAAVATRLK EEKLAASLSS SSSNQ
Length:495
Mass (Da):54,234
Last modified:August 16, 2004 - v1
Checksum:i5110D0935E94FD6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75535 Genomic DNA. Translation: CAH04733.1.
RefSeqiNP_001021107.1. NM_001025936.3.
UniGeneiCel.7424.

Genome annotation databases

EnsemblMetazoaiF14B4.2b; F14B4.2b; WBGene00008780.
GeneIDi172751.
KEGGicel:CELE_F14B4.2.
UCSCiF14B4.2b. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75535 Genomic DNA. Translation: CAH04733.1 .
RefSeqi NP_001021107.1. NM_001025936.3.
UniGenei Cel.7424.

3D structure databases

ProteinModelPortali Q6BET1.
SMRi Q6BET1. Positions 32-485.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai F14B4.2b ; F14B4.2b ; WBGene00008780 .
GeneIDi 172751.
KEGGi cel:CELE_F14B4.2.
UCSCi F14B4.2b. c. elegans.

Organism-specific databases

CTDi 172751.
WormBasei F14B4.2b ; CE36925 ; WBGene00008780 .

Phylogenomic databases

GeneTreei ENSGT00390000017159.
HOGENOMi HOG000162670.
KOi K00844.

Enzyme and pathway databases

Reactomei REACT_232743. Glucose transport.
REACT_254189. Regulation of gene expression in beta cells.
REACT_260911. Regulation of Glucokinase by Glucokinase Regulatory Protein.

Miscellaneous databases

NextBioi 876865.

Gene expression databases

ExpressionAtlasi Q6BET1. baseline.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ6BET1_CAEEL
AccessioniPrimary (citable) accession number: Q6BET1
Entry historyi
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: November 26, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3