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Protein

Phosphotransferase

Gene

hxk-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-170822. Regulation of Glucokinase by Glucokinase Regulatory Protein.
R-CEL-70153. Glucose transport.
R-CEL-70171. Glycolysis.

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
Name:hxk-1Imported
ORF Names:CELE_F14B4.2Imported, F14B4.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF14B4.2b; CE36925; WBGene00008780; hxk-1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiQ6BET1.
PaxDbiQ6BET1.

Expressioni

Gene expression databases

ExpressionAtlasiQ6BET1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi6239.F14B4.2a.2.

Structurei

3D structure databases

ProteinModelPortaliQ6BET1.
SMRiQ6BET1. Positions 32-485.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini34 – 228195Hexokinase_1InterPro annotationAdd
BLAST
Domaini234 – 475242Hexokinase_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.
HOGENOMiHOG000162670.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6BET1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATGKCSKV RPRFEMLKSM SIQNSIDVSN NQMIQEACQR LVLSDQQLRR
60 70 80 90 100
IMQSMEKSME QGLATSTKKV AVKMLPTYVD SVPNGTESGD FLALDLGGTN
110 120 130 140 150
FRVLHIKLQG KETKMTGKIF RVPESIMRGT GEALFDHIAG CMAKFMGEND
160 170 180 190 200
LKDAQKLPLG FTFSFPCEQE GLTKGKLVTW TKGFKASGVE GVDVVTLLHE
210 220 230 240 250
ACHRRKDIDI DVVALLNDTV GTLMACAFQE NSCQIGVIVG TGTNACYMER
260 270 280 290 300
LDRIPKLAGY VDEHGVTPEE MIINTEWGAF GDDGALDFLR TEWDEVVDRE
310 320 330 340 350
SINPGQHLYE KMISGMYMGE CARVVLEDLA KQGLLFGGNS DAISVPHCFP
360 370 380 390 400
TKFVSEIDSD LLEDDDRTFQ KTYQILEDIG VEMITANDCA NVAYVCSLIS
410 420 430 440 450
TRAAHLTAAG IAMLLNRMNK KHVTVGVDGS VYRFHPTYPT LLDAKIGELI
460 470 480 490
VGDIEYKLML SEDGSGRGAA LVAAVATRLK EEKLAASLSS SSSNQ
Length:495
Mass (Da):54,234
Last modified:August 16, 2004 - v1
Checksum:i5110D0935E94FD6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAH04733.1.
RefSeqiNP_001021107.1. NM_001025936.3.
UniGeneiCel.7424.

Genome annotation databases

EnsemblMetazoaiF14B4.2b; F14B4.2b; WBGene00008780.
GeneIDi172751.
KEGGicel:CELE_F14B4.2.
UCSCiF14B4.2b. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAH04733.1.
RefSeqiNP_001021107.1. NM_001025936.3.
UniGeneiCel.7424.

3D structure databases

ProteinModelPortaliQ6BET1.
SMRiQ6BET1. Positions 32-485.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F14B4.2a.2.

Proteomic databases

EPDiQ6BET1.
PaxDbiQ6BET1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF14B4.2b; F14B4.2b; WBGene00008780.
GeneIDi172751.
KEGGicel:CELE_F14B4.2.
UCSCiF14B4.2b. c. elegans.

Organism-specific databases

CTDi172751.
WormBaseiF14B4.2b; CE36925; WBGene00008780; hxk-1.

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.
HOGENOMiHOG000162670.
KOiK00844.

Enzyme and pathway databases

ReactomeiR-CEL-170822. Regulation of Glucokinase by Glucokinase Regulatory Protein.
R-CEL-70153. Glucose transport.
R-CEL-70171. Glycolysis.

Miscellaneous databases

NextBioi876865.

Gene expression databases

ExpressionAtlasiQ6BET1. baseline and differential.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ6BET1_CAEEL
AccessioniPrimary (citable) accession number: Q6BET1
Entry historyi
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: May 11, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.