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Protein

Ubiquitin-fold modifier-conjugating enzyme 1

Gene

Ufc1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei116Glycyl thioester intermediateBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-fold modifier-conjugating enzyme 1
Short name:
Ufm1-conjugating enzyme 1
Gene namesi
Name:Ufc1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 13

Organism-specific databases

RGDi1303313. Ufc1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000826151 – 167Ubiquitin-fold modifier-conjugating enzyme 1Add BLAST167

Proteomic databases

PaxDbiQ6BBI8.
PRIDEiQ6BBI8.

PTM databases

iPTMnetiQ6BBI8.
PhosphoSitePlusiQ6BBI8.

Expressioni

Gene expression databases

BgeeiENSRNOG00000003706.
GenevisibleiQ6BBI8. RN.

Interactioni

Subunit structurei

Interacts with UBA5. Interacts with UFL1. Interacts with KIRREL3.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000004938.

Structurei

3D structure databases

ProteinModelPortaliQ6BBI8.
SMRiQ6BBI8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3357. Eukaryota.
ENOG410ZBCX. LUCA.
GeneTreeiENSGT00390000008196.
HOGENOMiHOG000243361.
HOVERGENiHBG054254.
InParanoidiQ6BBI8.
KOiK12165.
OMAiEHFKPLW.
OrthoDBiEOG091G0MP6.
PhylomeDBiQ6BBI8.
TreeFamiTF313587.

Family and domain databases

InterProiIPR016135. UBQ-conjugating_enzyme/RWD.
IPR014806. Ufc1.
[Graphical view]
PANTHERiPTHR12921. PTHR12921. 1 hit.
PfamiPF08694. UFC1. 1 hit.
[Graphical view]
PIRSFiPIRSF008716. DUF1782. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6BBI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNAD
60 70 80 90 100
NDWFRLESNK EGTRWFGKCW YIHDFLKYEF DIEFEIPITY PTTAPEIAVP
110 120 130 140 150
ELDGKTAKMY RGGKICLTDH FKPLWARNVP KFGLAHLMAL GLGPWLAVEV
160
PDLIQKGVIQ HKEKCNQ
Length:167
Mass (Da):19,492
Last modified:September 13, 2004 - v1
Checksum:iB78DB4F2DC1FEE1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB186051 mRNA. Translation: BAD34943.1.
BC087648 mRNA. Translation: AAH87648.1.
RefSeqiNP_001003709.1. NM_001003709.2.
XP_006250313.1. XM_006250251.2.
UniGeneiRn.8050.

Genome annotation databases

EnsembliENSRNOT00000004938; ENSRNOP00000004938; ENSRNOG00000003706.
GeneIDi445268.
KEGGirno:445268.
UCSCiRGD:1303313. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB186051 mRNA. Translation: BAD34943.1.
BC087648 mRNA. Translation: AAH87648.1.
RefSeqiNP_001003709.1. NM_001003709.2.
XP_006250313.1. XM_006250251.2.
UniGeneiRn.8050.

3D structure databases

ProteinModelPortaliQ6BBI8.
SMRiQ6BBI8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000004938.

PTM databases

iPTMnetiQ6BBI8.
PhosphoSitePlusiQ6BBI8.

Proteomic databases

PaxDbiQ6BBI8.
PRIDEiQ6BBI8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000004938; ENSRNOP00000004938; ENSRNOG00000003706.
GeneIDi445268.
KEGGirno:445268.
UCSCiRGD:1303313. rat.

Organism-specific databases

CTDi51506.
RGDi1303313. Ufc1.

Phylogenomic databases

eggNOGiKOG3357. Eukaryota.
ENOG410ZBCX. LUCA.
GeneTreeiENSGT00390000008196.
HOGENOMiHOG000243361.
HOVERGENiHBG054254.
InParanoidiQ6BBI8.
KOiK12165.
OMAiEHFKPLW.
OrthoDBiEOG091G0MP6.
PhylomeDBiQ6BBI8.
TreeFamiTF313587.

Miscellaneous databases

PROiQ6BBI8.

Gene expression databases

BgeeiENSRNOG00000003706.
GenevisibleiQ6BBI8. RN.

Family and domain databases

InterProiIPR016135. UBQ-conjugating_enzyme/RWD.
IPR014806. Ufc1.
[Graphical view]
PANTHERiPTHR12921. PTHR12921. 1 hit.
PfamiPF08694. UFC1. 1 hit.
[Graphical view]
PIRSFiPIRSF008716. DUF1782. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUFC1_RAT
AccessioniPrimary (citable) accession number: Q6BBI8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: September 13, 2004
Last modified: November 2, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.