SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6B8T1

- ODPB_GRATL

UniProt

Q6B8T1 - ODPB_GRATL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Pyruvate dehydrogenase E1 component subunit beta

Gene
pdhB, odpB, Grc000123
Organism
Gracilaria tenuistipitata var. liui (Red alga)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activityi

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactori

Thiamine pyrophosphate By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei60 – 601Thiamine pyrophosphate By similarity

GO - Molecular functioni

  1. pyruvate dehydrogenase (acetyl-transferring) activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Pyruvate, Thiamine pyrophosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate dehydrogenase E1 component subunit beta (EC:1.2.4.1)
Gene namesi
Name:pdhB
Synonyms:odpB
Ordered Locus Names:Grc000123
Encoded oniPlastid; Chloroplast
OrganismiGracilaria tenuistipitata var. liui (Red alga)
Taxonomic identifieri285951 [NCBI]
Taxonomic lineageiEukaryotaRhodophytaFlorideophyceaeGracilarialesGracilariaceaeGracilaria

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 323323Pyruvate dehydrogenase E1 component subunit betaPRO_0000280108Add
BLAST

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta chain By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ6B8T1.

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.920. 1 hit.
3.40.50.970. 1 hit.
InterProiIPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view]
PfamiPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.
SSF52922. SSF52922. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6B8T1-1 [UniParc]FASTAAdd to Basket

« Hide

MTEVLMFDAL REATDEEMQN DSSVFILGED VGHYGGSYKV TKDLHSKYGD    50
LRVLDTPIAE NSFMGMAIGA AITGLRPIVE GMNMSFLLLA FNQISNNAGM 100
LRYTSGGNFQ IPIVIRGPGG VGRQLGAEHS QRLEAYFQAI PGLKIVACST 150
PYNAKGLLKS AIRDNNPVIF FEHVLLYNLK DELPNDEYFL PLDKAELVRD 200
GLDVTILTYS RMRHHVMQAV VDLVNDGYNP EVIDLISLKP LDITSIAQSL 250
MKTHKLIIVE ECMKTGGIGA EIIAQINDNY FDFLDAPIVR LSSQDIPTPY 300
NGKLEKATVI YPQQIIEAVK SIV 323
Length:323
Mass (Da):35,742
Last modified:September 13, 2004 - v1
Checksum:iEF7821FA426BFEED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY673996 Genomic DNA. Translation: AAT79704.1.
RefSeqiYP_063629.1. NC_006137.1.

Genome annotation databases

GeneIDi2943994.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY673996 Genomic DNA. Translation: AAT79704.1 .
RefSeqi YP_063629.1. NC_006137.1.

3D structure databases

ProteinModelPortali Q6B8T1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2943994.

Family and domain databases

Gene3Di 3.40.50.920. 1 hit.
3.40.50.970. 1 hit.
InterProi IPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view ]
Pfami PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view ]
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 1 hit.
SSF52922. SSF52922. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative analysis of the complete plastid genome sequence of the red alga Gracilaria tenuistipitata var. liui provides insights into the evolution of rhodoplasts and their relationship to other plastids."
    Hagopian J.C., Reis M., Kitajima J.P., Bhattacharya D., de Oliveira M.C.
    J. Mol. Evol. 59:464-477(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiODPB_GRATL
AccessioniPrimary (citable) accession number: Q6B8T1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: September 13, 2004
Last modified: June 11, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Similar proteinsi