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Protein
Submitted name:

Alcohol dehydrogenase Class VI

Gene

ADH8

Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Zn2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Alcohol dehydrogenase Class VIImported
Gene namesi
Name:ADH8Imported
OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)Imported
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias

Interactioni

Protein-protein interaction databases

STRINGi8090.ENSORLP00000022083.

Structurei

3D structure databases

ProteinModelPortaliQ6B4J3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 373PKS_ERInterPro annotationAdd BLAST357

Sequence similaritiesi

Belongs to the zinc-containing alcohol dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0022. Eukaryota.
COG1062. LUCA.
HOGENOMiHOG000294674.
HOVERGENiHBG000195.
KOiK00121.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 2 hits.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 2 hits.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00059. ADH_ZINC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6B4J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAGKVIKC KAAVAWEPNK PLVIEDIEVA PPQANEVRIK IVATGVCHTD
60 70 80 90 100
LYHLFEGMHK DGFPAVLGHE GAGIVESVGP GVSEFQPGDR VIPLFISQCR
110 120 130 140 150
ECRFCKSPKT NQCEKGWAAD HYDVMALADS RFTCKGKKVL QFMGASTFSE
160 170 180 190 200
YTVMNQIAVA KIDPAAPLDK VCLLGCGVCT GFGAAVNTAK VEPGSTCAVF
210 220 230 240 250
GLGAVGLAAV MGCKFAGAKR IFAVDTNPEK AEKARVFGAT DFVNPKDYNK
260 270 280 290 300
PISKVLAEMT NGGVDYSLEC VGNVDVMRSA LESCMKGWGV SVVVGWTDKH
310 320 330 340 350
DFSARPIQLI AGRTWKGTLF GGFKSKDGVP QMVKAYMERK VKLDEFITHN
360 370
MTLTQVNEAI ELMKRGGCIR TVLSVSRQ
Length:378
Mass (Da):40,713
Last modified:September 13, 2004 - v1
Checksum:i490B28AF50631635
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY682722 mRNA. Translation: AAT81592.1.
RefSeqiNP_001098266.1. NM_001104796.1.
UniGeneiOla.16023.

Genome annotation databases

GeneIDi100049415.
KEGGiola:100049415.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY682722 mRNA. Translation: AAT81592.1.
RefSeqiNP_001098266.1. NM_001104796.1.
UniGeneiOla.16023.

3D structure databases

ProteinModelPortaliQ6B4J3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8090.ENSORLP00000022083.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100049415.
KEGGiola:100049415.

Phylogenomic databases

eggNOGiKOG0022. Eukaryota.
COG1062. LUCA.
HOGENOMiHOG000294674.
HOVERGENiHBG000195.
KOiK00121.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 2 hits.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 2 hits.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00059. ADH_ZINC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6B4J3_ORYLA
AccessioniPrimary (citable) accession number: Q6B4J3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: October 5, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.