Q6AZV8 (Q6AZV8_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
4-hydroxyphenylpyruvate dioxygenase PIRNR PIRNR009283

Gene names

Name:	hpd ZFIN ZDB-GENE-040808-62
ORF Names:	zgc:92456 ZFIN ZDB-GENE-040808-62

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAH77167.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	393 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Cofactor	Binds 1 iron ion per subunit By similarity. PIRSR PIRSR009283-1
Sequence similarities	Belongs to the 4HPPD family. PIRSR PIRSR009283-1 PIRNR PIRNR009283

Ontologies

Keywords
Ligand	Iron PIRSR PIRSR009283-1 Metal-binding PIRSR PIRSR009283-1 Pyruvate EMBL AAH77167.1
Molecular function	Dioxygenase EMBL AAH77167.1 Oxidoreductase
Gene Ontology (GO)
Biological process	aromatic amino acid family metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-hydroxyphenylpyruvate dioxygenase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	183	1	Iron By similarity PIRSR PIRSR009283-1
	Metal binding	266	1	Iron By similarity PIRSR PIRSR009283-1
	Metal binding	349	1	Iron By similarity PIRSR PIRSR009283-1

Sequences

	Sequence		Length	Mass (Da)
	Q6AZV8 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: 39E76BB1DF138105	FASTA	393	44,653
	10 20 30 40 50 60 MTSYIDKGEK HEEGKFICFD HITFWVGNAK QAASYYCNKL GFEPLAYRGL ETGSREVVSH 70 80 90 100 110 120 AVKQGKIIYV FTSALNPGNK EMGDHLVKHG DGVKDVAFTV ENCDFLVEKA RERGAIIIKE 130 140 150 160 170 180 SHAVEDKFGR VKMAVVQTYG DTTHTFVERT GYNGLFLPGF HAPLFCDPFL AKLPSGKLDF 190 200 210 220 230 240 IDHVVGNQPD SEMVPIVEWY QRNLLFHRFW SVDDKQLQTE YSALRSIVVA NYEETVKMPI 250 260 270 280 290 300 NEPAMGKRKS QIQEYVEYYG GAGVQHIAMN TSDIISAIRN LKERGMEFMS VPDTYYQQLK 310 320 330 340 350 360 EKLKLSKVRI IEDLNILEEL KILVDYDDNG YLLQIFTKPV QDRPTVFLEV IQRHNHQGFG 370 380 390 AGNFKSLFEA IEADQNARGN LTILTPNGTT ETL

References

[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Whole EMBL AAH77167.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC077167 mRNA. Translation: AAH77167.1.
IPI	IPI00488563.
RefSeq	NP_001003742.1. NM_001003742.1.
UniGene	Dr.86760.
3D structure databases
ProteinModelPortal	Q6AZV8.
SMR	Q6AZV8. Positions 8-366.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6AZV8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	445287.
KEGG	dre:445287.
Organism-specific databases
CTD	3242.
ZFIN	ZDB-GENE-040808-62. hpd.
Phylogenomic databases
eggNOG	fiNOG14988.
GeneTree	ENSGT00530000063474.
HOVERGEN	HBG005987.
InParanoid	Q6AZV8.
Gene expression databases
Bgee	Q6AZV8.
Family and domain databases
InterPro	IPR005956. 4OHPhenylPyrv_dOase. IPR004360. Glyas_Fos-R_dOase. [Graphical view]
KO	K00457.
PANTHER	PTHR11959. HPP_dOase. 1 hit.
Pfam	PF00903. Glyoxalase. 2 hits. [Graphical view]
PIRSF	PIRSF009283. HPP_dOase. 1 hit.
TIGRFAMs	TIGR01263. 4HPPD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6AZV8_DANRE

Accession

Primary (citable) accession number: Q6AZV8

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2004
Last sequence update:	September 13, 2004
Last modified:	November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)