hsp90ab1

Functionⁱ

GO - Molecular functionⁱ

ATP binding Source: InterPro
unfolded protein binding Source: InterPro

GO - Biological processⁱ

protein folding Source: InterPro
response to stress Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Hsp90betaImported Submitted name: Hsp90beta proteinImported
Gene namesⁱ	Name:hsp90ab1Imported Synonyms:hsp90betaImported ORF Names:XELAEV_18028538mgImported
Organismⁱ	Xenopus laevis (African clawed frog)Imported
Taxonomic identifierⁱ	8355 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus
Proteomesⁱ	UP000186698 Componentⁱ: Chromosome 5s

Organism-specific databases

Xenbaseⁱ	XB-GENE-866421. hsp90ab1.

Xenbaseⁱ

XB-GENE-866421. hsp90ab1.

Interactionⁱ

GO - Molecular functionⁱ

unfolded protein binding Source: InterPro

Complete GO annotation...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	35 – 189	HATPase_cInterPro annotationAdd BLAST		155

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	216 – 243	Sequence analysisAdd BLAST		28

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

HOVERGENⁱ	HBG007374.
KEGG Orthology (KO) More...KOⁱ	K04079.

Family and domain databases

Gene3Dⁱ	3.30.565.10. 1 hit.
HAMAPⁱ	MF_00505. HSP90. 1 hit.
InterProⁱ	View protein in InterPro IPR003594. HATPase_C. IPR019805. Heat_shock_protein_90_CS. IPR001404. Hsp90_fam. IPR020575. Hsp90_N. IPR020568. Ribosomal_S5_D2-typ_fold.
PANTHERⁱ	PTHR11528. PTHR11528. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02518. HATPase_c. 1 hit. PF00183. HSP90. 1 hit.
PIRSFⁱ	PIRSF002583. Hsp90. 1 hit.
PRINTSⁱ	PR00775. HEATSHOCK90.
SMARTⁱ	View protein in SMART SM00387. HATPase_c. 1 hit.
SUPFAMⁱ	SSF54211. SSF54211. 1 hit. SSF55874. SSF55874. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00298. HSP90. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q6AZV1-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MPEVAHNGEE EVETFAFQAE IAQLMSLIIN TFYSNKEIFL RELISNASDA 
        60         70         80         90        100
LDKIRYESLT DPSKLDSGKD LKIDIIPNRL ERTLTMIDTG IGMTKADLIN 
       110        120        130        140        150
NLGTIAKSGT KAFMEALQAG ADISMIGQFG VGFYSAYLVA EKVVVITKHN 
       160        170        180        190        200
DDEQYAWESS AGGSFTVKVD TGEPIGRGTK VILHLKEDQT EYLEEKRVKE 
       210        220        230        240        250
TVKKHSQFIG YPITLYLEKE REKEISDDEA EEEKEEKKEE EGENDKPKIE 
       260        270        280        290        300
DVGSDEEEEG KDKKKKTKKI KEKYIDQEEL NKTKPIWTRN PDDITQEEYG 
       310        320        330        340        350
EFYKSLTNDW EDHLAVKHFS VEGQLEFRAL LFIPRRAPFD LFENKKKKNN 
       360        370        380        390        400
IKLYVRRVFI MDSCDELIPE YLNFVRGVVD SEDLPLNISR EMLQQSKILK 
       410        420        430        440        450
VIRKNIVKKC LELFCELAED KENYKKFYEG FSKNLKLGIH EDSTNRKKLS 
       460        470        480        490        500
ELLRYHTSQT GDEMASLTEY VSRMKENQKS IYYITGESKD QVANSAFVER 
       510        520        530        540        550
VRKRGFEVVY MTEPIDEYCV QQLKEFDGKT LVSVTKEGLE LPEDEEEKKT 
       560        570        580        590        600
MEENKTKFES LCKLMKEILD KKVEKVTVSN RLVSSPCCIV TSTYGWTANM 
       610        620        630        640        650
ERIMKAQALR DNSTMGYMMA KKHLEINPEH PIVETLRQKA DTDKNDKAVK 
       660        670        680        690        700
DLVVLLFETA LLSSGFSLDD PQTHSNRIYR MIKLGLGIDD DDAPIEEASP 
       710        720 
SVPDDIPPLE GEEDASRMEE VD

Length:722

Mass (Da):82,957

Last modified:September 13, 2004 - v1

Checksum:ⁱ69EBACA626E5C3CA

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC077195 mRNA. Translation: AAH77195.1. AY785160 mRNA. Translation: AAV41061.1. CM004475 Genomic DNA. Translation: OCT77446.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001086624.1. NM_001093155.1.
UniGeneⁱ	Xl.29353.

Genome annotation databases

GeneIDⁱ	446459.
KEGGⁱ	xla:446459.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC077195 mRNA. Translation: AAH77195.1. AY785160 mRNA. Translation: AAV41061.1. CM004475 Genomic DNA. Translation: OCT77446.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001086624.1. NM_001093155.1.
UniGeneⁱ	Xl.29353.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	446459.
KEGGⁱ	xla:446459.

Organism-specific databases

CTDⁱ	446459.
Xenbaseⁱ	XB-GENE-866421. hsp90ab1.

Phylogenomic databases

HOVERGENⁱ	HBG007374.
KEGG Orthology (KO) More...KOⁱ	K04079.

Family and domain databases

Gene3Dⁱ	3.30.565.10. 1 hit.
HAMAPⁱ	MF_00505. HSP90. 1 hit.
InterProⁱ	View protein in InterPro IPR003594. HATPase_C. IPR019805. Heat_shock_protein_90_CS. IPR001404. Hsp90_fam. IPR020575. Hsp90_N. IPR020568. Ribosomal_S5_D2-typ_fold.
PANTHERⁱ	PTHR11528. PTHR11528. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02518. HATPase_c. 1 hit. PF00183. HSP90. 1 hit.
PIRSFⁱ	PIRSF002583. Hsp90. 1 hit.
PRINTSⁱ	PR00775. HEATSHOCK90.
SMARTⁱ	View protein in SMART SM00387. HATPase_c. 1 hit.
SUPFAMⁱ	SSF54211. SSF54211. 1 hit. SSF55874. SSF55874. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00298. HSP90. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q6AZV1_XENLA
Accessionⁱ	Q6AZV1Primary (citable) accession number: Q6AZV1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	September 13, 2004
	Last sequence update:	September 13, 2004
	Last modified:	June 7, 2017
	This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - Q6AZV1 (Q6AZV1_XENLA)

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Hsp90beta

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6AZV1 (Q6AZV1_XENLA)

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Hsp90beta

hsp90ab1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ