Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

K-ras

Gene

kras

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • embryonic cranial skeleton morphogenesis Source: ZFIN
  • heart development Source: ZFIN
  • hemopoiesis Source: ZFIN
  • small GTPase mediated signal transduction Source: InterPro

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
K-rasImported
Submitted name:
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homologImported
Gene namesi
Name:krasImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 25

Organism-specific databases

ZFINiZDB-GENE-040808-67. kras.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSDARG00000010844.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000021124.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0395. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00860000133672.
HOGENOMiHOG000233973.
HOVERGENiHBG009351.
KOiK07827.
OMAiKKSRTRC.
OrthoDBiEOG091G0UAU.
TreeFamiTF312796.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR020849. Small_GTPase_Ras.
PANTHERiPTHR24070. PTHR24070. 1 hit.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51421. RAS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AZA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET
60 70 80 90 100
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI
110 120 130 140 150
KRVKDSEDVP MVLVGNKCDL QSHNVDSKQA QDLARSYGIP FIETSAKTRQ
160 170 180
GVDDAFYTLV REIRKHKEKM SKEGKKKKKK SKTKCALM
Length:188
Mass (Da):21,421
Last modified:September 13, 2004 - v1
Checksum:i3E35BB6DEA877ED1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ976913 Genomic DNA. No translation available.
BC078646 mRNA. Translation: AAH78646.1.
DQ486868 mRNA. Translation: ABF46832.1.
RefSeqiNP_001003744.1. NM_001003744.1.
XP_017209704.1. XM_017354215.1.
UniGeneiDr.20193.

Genome annotation databases

EnsembliENSDART00000009126; ENSDARP00000021124; ENSDARG00000010844.
GeneIDi103909873.
445289.
KEGGidre:445289.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ976913 Genomic DNA. No translation available.
BC078646 mRNA. Translation: AAH78646.1.
DQ486868 mRNA. Translation: ABF46832.1.
RefSeqiNP_001003744.1. NM_001003744.1.
XP_017209704.1. XM_017354215.1.
UniGeneiDr.20193.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000021124.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000009126; ENSDARP00000021124; ENSDARG00000010844.
GeneIDi103909873.
445289.
KEGGidre:445289.

Organism-specific databases

CTDi3845.
ZFINiZDB-GENE-040808-67. kras.

Phylogenomic databases

eggNOGiKOG0395. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00860000133672.
HOGENOMiHOG000233973.
HOVERGENiHBG009351.
KOiK07827.
OMAiKKSRTRC.
OrthoDBiEOG091G0UAU.
TreeFamiTF312796.

Gene expression databases

BgeeiENSDARG00000010844.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR020849. Small_GTPase_Ras.
PANTHERiPTHR24070. PTHR24070. 1 hit.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51421. RAS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6AZA4_DANRE
AccessioniPrimary (citable) accession number: Q6AZA4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: March 15, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.