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Protein
Submitted name:

CD6 molecule

Gene

CD6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
CD6 moleculeImported
Gene namesi
Name:CD6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei399 – 424HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26230

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500427176518 – 668Sequence analysisAdd BLAST651

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi230 ↔ 240PROSITE-ProRule annotation
Disulfide bondi330 ↔ 340PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PeptideAtlasiQ6AZ88
PRIDEiQ6AZ88

Expressioni

Gene expression databases

GenevisibleiQ6AZ88 HS

Structurei

3D structure databases

ProteinModelPortaliQ6AZ88
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 156SRCRInterPro annotationAdd BLAST112
Domaini161 – 260SRCRInterPro annotationAdd BLAST100
Domaini265 – 361SRCRInterPro annotationAdd BLAST97

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9E Eukaryota
ENOG410YC2B LUCA
HOVERGENiHBG005289
KOiK06456

Family and domain databases

Gene3Di3.10.250.10, 3 hits
InterProiView protein in InterPro
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
PfamiView protein in Pfam
PF00530 SRCR, 3 hits
PRINTSiPR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00202 SR, 3 hits
SUPFAMiSSF56487 SSF56487, 3 hits
PROSITEiView protein in PROSITE
PS00420 SRCR_1, 1 hit
PS50287 SRCR_2, 3 hits

Sequencei

Sequence statusi: Complete.

Q6AZ88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLFFGITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG
60 70 80 90 100
SSSCSGTVEV RLEASWEPAC GALWDSRAAE AVCRALGCGG AEAASQLAPP
110 120 130 140 150
TPELPPPPAA GNTSVAANAT LAGAPALLCS GAEWRLCEVV EHACRSDGRR
160 170 180 190 200
ARVTCAENRA LRLVDGGGAC AGRVEMLEHG EWGSVCDDTW DLEDAHVVCR
210 220 230 240 250
QLGCGWAVQA LPGLHFMPGR GPIHRDQVNC SGAEAYLWDC PGLPGQHYCG
260 270 280 290 300
HKEDAGVVCS EHQSWRLTGG ADRCEGQVEV HFRGVWNTVC DSEWYPSEAK
310 320 330 340 350
VLCQSLGCGT AVERPKGLPH SLSGRMYYSC NGEELTLSNC SWRFNNSNLC
360 370 380 390 400
SQSLAARVLC SASRSLHNLS TPEVPASVQT VTIESSVTVK IENKESRELM
410 420 430 440 450
LLIPSIVLGI LLLGSLIFIA FILLRIKGKY ALPVMVNHQH LPTTIPAGSN
460 470 480 490 500
SYQPVPITIP KEVFMLPIQV QAPPPEDSDS GSDSDYEHYD FSAQPPVALT
510 520 530 540 550
TFYNSQRHRV TDEEVQQSRF QMPPLEEGLE ELHASHIPTA NPGHCITDPP
560 570 580 590 600
SLGPQYHPRS NSESSTSSGE DYCNSPKSKL PPWNPQVFSS ERSSFLEQPP
610 620 630 640 650
NLELASTQPA FSAGPPADDS SSTSSGEWYQ NFQPPPQPPS EEQFGCPGSP
660
SPQPDSTDND DYDDISAA
Length:668
Mass (Da):71,889
Last modified:September 13, 2004 - v1
Checksum:i4D2C01A6FFEDF1D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC078669 mRNA Translation: AAH78669.1
RefSeqiNP_006716.3, NM_006725.4
UniGeneiHs.744366

Genome annotation databases

GeneIDi923
KEGGihsa:923

Similar proteinsi

Entry informationi

Entry nameiQ6AZ88_HUMAN
AccessioniPrimary (citable) accession number: Q6AZ88
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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