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Protein

Golgin subfamily A member 7

Gene

Golga7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS (By similarity).By similarity

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Recommended name:
Golgin subfamily A member 7
Gene namesi
Name:Golga7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi1359725. Golga7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002139791 – 137Golgin subfamily A member 7Add BLAST137

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi69S-palmitoyl cysteineBy similarity1
Lipidationi72S-palmitoyl cysteineBy similarity1

Post-translational modificationi

Palmitoylated on Cys-69 and Cys-72; which is required for Golgi localization and interaction with GOLGA3.By similarity

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ6AYQ1.
PRIDEiQ6AYQ1.

PTM databases

iPTMnetiQ6AYQ1.
PhosphoSitePlusiQ6AYQ1.

Expressioni

Gene expression databases

BgeeiENSRNOG00000017956.
GenevisibleiQ6AYQ1. RN.

Interactioni

Subunit structurei

Interacts with GOLGA3. Interacts with ZDHHC9 (By similarity).By similarity

Protein-protein interaction databases

BioGridi262489. 1 interactor.
STRINGi10116.ENSRNOP00000033324.

Family & Domainsi

Sequence similaritiesi

Belongs to the ERF4 family.Curated

Phylogenomic databases

eggNOGiKOG4069. Eukaryota.
ENOG4111NS1. LUCA.
GeneTreeiENSGT00390000000134.
HOGENOMiHOG000010289.
HOVERGENiHBG054534.
InParanoidiQ6AYQ1.
OMAiDKIYAPR.
OrthoDBiEOG091G0R12.
PhylomeDBiQ6AYQ1.
TreeFamiTF313115.

Family and domain databases

InterProiView protein in InterPro
IPR019383. Golgin_A_7/ERF4.
PfamiView protein in Pfam
PF10256. Erf4. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AYQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPQQAPVSG KVFIQRDYSS GTRCQFQTKF PAELENRVDR QQFEETVRTL
60 70 80 90 100
NNLYAEAEKL GGQSYLEGCL ACLTAYTIFL CMETHYEKVL KKVSKYIQEQ
110 120 130
NEKIYAPQGL LLTDPIERGL RVIEITIYED RGVSSGR
Length:137
Mass (Da):15,778
Last modified:September 13, 2004 - v1
Checksum:iDA19965461E4BA98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC078959 mRNA. Translation: AAH78959.1.
RefSeqiNP_001007732.1. NM_001007731.1.
XP_017455674.1. XM_017600185.1.
UniGeneiRn.4105.

Genome annotation databases

EnsembliENSRNOT00000030960; ENSRNOP00000033324; ENSRNOG00000017956.
GeneIDi361171.
KEGGirno:361171.
UCSCiRGD:1359725. rat.

Similar proteinsi

Entry informationi

Entry nameiGOGA7_RAT
AccessioniPrimary (citable) accession number: Q6AYQ1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: September 13, 2004
Last modified: June 7, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families