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Protein

Probable allantoicase

Gene

Allc

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.

Catalytic activityi

Allantoate + H2O = (S)-ureidoglycolate + urea.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable allantoicase (EC:3.5.3.4)
Alternative name(s):
Allantoate amidinohydrolase
Gene namesi
Name:Allc
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi621804. Allc.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 413413Probable allantoicasePRO_0000205908Add
BLAST

Proteomic databases

PaxDbiQ6AYP0.
PRIDEiQ6AYP0.

Expressioni

Gene expression databases

BgeeiENSRNOG00000008299.
ExpressionAtlasiQ6AYP0. baseline.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011048.

Structurei

3D structure databases

ProteinModelPortaliQ6AYP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the allantoicase family.Curated

Phylogenomic databases

eggNOGiKOG4145. Eukaryota.
COG4266. LUCA.
GeneTreeiENSGT00390000001793.
HOGENOMiHOG000256158.
HOVERGENiHBG004209.
InParanoidiQ6AYP0.
KOiK01477.
OMAiKWKPLLP.
OrthoDBiEOG091G0BRW.
PhylomeDBiQ6AYP0.

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
InterProiIPR005164. Allantoicase.
IPR015908. Allantoicase_dom.
IPR008979. Galactose-bd-like.
[Graphical view]
PANTHERiPTHR12045. PTHR12045. 1 hit.
PfamiPF03561. Allantoicase. 2 hits.
[Graphical view]
PIRSFiPIRSF016516. Allantoicase. 1 hit.
SUPFAMiSSF49785. SSF49785. 2 hits.
TIGRFAMsiTIGR02961. allantoicase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AYP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADTPKEGKL TRFLDFTQLI DLASECVGGK VLFATDDFFG PAENLIKSNN
60 70 80 90 100
PSFKENEYTE FGKWVDGWET RRKRIPGHDW CVIQLGIQGI IRGIDVDISY
110 120 130 140 150
FSGNYAPRMS IQAANLSEDT VTNIPPRGVK MGAAATSEEF VAITELKSHS
160 170 180 190 200
WDYLVPMSEL KPGDPDSSHN YFFVNSQQRW THIRLNIFPD GGVARLRVYG
210 220 230 240 250
TGQRDWAALD STEPVDLVAI AFGGVCVGFS NAHFGHPNNM IGVGDPKSIA
260 270 280 290 300
DGWETARRLD RPPVLEGNEN GFLQVPGCEW AVFRLAHPGV ITQIEIDTKY
310 320 330 340 350
FKGNSPDSCK VDGCILTTLE EEDMIRQKWS LPAHKWKPLL PVTKLTPNQN
360 370 380 390 400
HLLDSLTLEL QDVITHARIT IAPDGGVSRL RLKGFPSSIC LLRPLREKPM
410
LRFSLKAGFR ANL
Length:413
Mass (Da):46,037
Last modified:September 13, 2004 - v1
Checksum:i58DF636B0566B747
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti227 – 2271V → G in AAM74035 (PubMed:14745534).Curated
Sequence conflicti258 – 2581R → S in AAM74035 (PubMed:14745534).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC078971 mRNA. Translation: AAH78971.1.
AF480062 mRNA. Translation: AAM74035.1.
RefSeqiNP_001013055.1. NM_001013037.1.
XP_006240006.1. XM_006239944.2.
UniGeneiRn.92436.

Genome annotation databases

EnsembliENSRNOT00000011048; ENSRNOP00000011048; ENSRNOG00000008299.
GeneIDi246758.
KEGGirno:246758.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC078971 mRNA. Translation: AAH78971.1.
AF480062 mRNA. Translation: AAM74035.1.
RefSeqiNP_001013055.1. NM_001013037.1.
XP_006240006.1. XM_006239944.2.
UniGeneiRn.92436.

3D structure databases

ProteinModelPortaliQ6AYP0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011048.

Proteomic databases

PaxDbiQ6AYP0.
PRIDEiQ6AYP0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000011048; ENSRNOP00000011048; ENSRNOG00000008299.
GeneIDi246758.
KEGGirno:246758.

Organism-specific databases

CTDi55821.
RGDi621804. Allc.

Phylogenomic databases

eggNOGiKOG4145. Eukaryota.
COG4266. LUCA.
GeneTreeiENSGT00390000001793.
HOGENOMiHOG000256158.
HOVERGENiHBG004209.
InParanoidiQ6AYP0.
KOiK01477.
OMAiKWKPLLP.
OrthoDBiEOG091G0BRW.
PhylomeDBiQ6AYP0.

Miscellaneous databases

PROiQ6AYP0.

Gene expression databases

BgeeiENSRNOG00000008299.
ExpressionAtlasiQ6AYP0. baseline.

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
InterProiIPR005164. Allantoicase.
IPR015908. Allantoicase_dom.
IPR008979. Galactose-bd-like.
[Graphical view]
PANTHERiPTHR12045. PTHR12045. 1 hit.
PfamiPF03561. Allantoicase. 2 hits.
[Graphical view]
PIRSFiPIRSF016516. Allantoicase. 1 hit.
SUPFAMiSSF49785. SSF49785. 2 hits.
TIGRFAMsiTIGR02961. allantoicase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiALLC_RAT
AccessioniPrimary (citable) accession number: Q6AYP0
Secondary accession number(s): Q8K470
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2004
Last modified: September 7, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.