Q6AYK4 (B2L14_RAT) Reviewed, UniProtKB/Swiss-Prot
Last modified
October 19, 2011.
Version 54.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Apoptosis facilitator Bcl-2-like protein 14 Short name=Bcl2-L-14 | ||
| Gene names |
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| Organism | Rattus norvegicus (Rat) | ||
| Taxonomic identifier | 10116 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus |
Protein attributes
| Sequence length | 326 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Plays a role in apoptosis. |
| Subcellular location | Cytoplasm By similarity. |
| Post-translational modification | Phosphorylated by MELK, leading to inhibit its pro-apoptotic function By similarity. |
| Sequence similarities | Belongs to the Bcl-2 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Apoptosis |
| Cellular component | Cytoplasm |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | apoptotic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of apoptotic processInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BC079010 mRNA. Translation: AAH79010.1. |
| IPI | IPI00390142. |
| RefSeq | NP_001019509.1. NM_001024338.1. |
| UniGene | Rn.162775. |
3D structure databases | |
| ProteinModelPortal | Q6AYK4. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q6AYK4. |
PTM databases | |
| PhosphoSite | Q6AYK4. |
Proteomic databases | |
| PRIDE | Q6AYK4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSRNOT00000032229; ENSRNOP00000029468; ENSRNOG00000028632. |
| GeneID | 500348. |
| KEGG | rno:500348. |
| NMPDR | fig|10116.3.peg.22412. |
| UCSC | NM_001024338. rat. |
Organism-specific databases | |
| CTD | 79370. |
| RGD | 1562777. Bcl2l14. |
Phylogenomic databases | |
| eggNOG | roNOG13007. |
| GeneTree | ENSGT00390000007293. |
| HOVERGEN | HBG050649. |
| InParanoid | Q6AYK4. |
| OMA | KKDKALM. |
| OrthoDB | EOG4Q58Q6. |
| PhylomeDB | Q6AYK4. |
Gene expression databases | |
| ArrayExpress | Q6AYK4. |
| Genevestigator | Q6AYK4. |
| GermOnline | ENSRNOG00000028632. Rattus norvegicus. |
Family and domain databases | |
| InterPro | IPR002475. Bcl2-like_apoptosis. [Graphical view] |
| PROSITE | PS50062. BCL2_FAMILY. 1 hit. PS01258. BH2. False negative. PS01259. BH3. False negative. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 705915. |
Entry information
| Entry name | B2L14_RAT | ||||||||
| Accession | Primary (citable) accession number: Q6AYK4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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