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Protein

INO80 complex subunit E

Gene

Ino80e

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-RNO-5696394. DNA Damage Recognition in GG-NER.

Names & Taxonomyi

Protein namesi
Recommended name:
INO80 complex subunit E
Alternative name(s):
Coiled-coil domain-containing protein 95
Gene namesi
Name:Ino80e
Synonyms:Ccdc95
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1359572. Ino80e.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244INO80 complex subunit EPRO_0000234293Add
BLAST

Proteomic databases

PaxDbiQ6AYH2.
PRIDEiQ6AYH2.

Expressioni

Gene expression databases

GenevisibleiQ6AYH2. RN.

Interactioni

Subunit structurei

Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027034.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili10 – 5445Sequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi91 – 210120Pro-richAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IIN3. Eukaryota.
ENOG4111S1J. LUCA.
GeneTreeiENSGT00390000011918.
HOGENOMiHOG000047138.
HOVERGENiHBG063770.
InParanoidiQ6AYH2.
KOiK11669.
OMAiMPPHTIL.
OrthoDBiEOG7034J4.
PhylomeDBiQ6AYH2.
TreeFamiTF326931.

Family and domain databases

InterProiIPR026678. INO80E.
[Graphical view]
PANTHERiPTHR21812. PTHR21812. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AYH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGPADGEVD YKKKYRNLKR KLKFLIYEHE CFQEELRKAQ RKLLKVSRDK
60 70 80 90 100
SFLLDRLLQY ENVDEDSSDS DATASSDNSE TEGTPKLSDT PAPKRKRSPP
110 120 130 140 150
MGGAPSPSSL SLPPSSGFPL QTSGAPSPYL SSLASPPYPP FPSDYLALQL
160 170 180 190 200
PEPSPLRPKL EKRPRLPRKL KMAVGPPDCP VGGPLAFPAR GSGASVGAAL
210 220 230 240
TPLPPPKMPP HTILSTVPQQ MFSDAGSGDD ALDGDDDLVI DIPE
Length:244
Mass (Da):26,358
Last modified:September 13, 2004 - v1
Checksum:iA28776CEC894E0F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079045 mRNA. Translation: AAH79045.1.
RefSeqiNP_001013922.1. NM_001013900.1.
UniGeneiRn.3179.

Genome annotation databases

EnsembliENSRNOT00000027033; ENSRNOP00000027034; ENSRNOG00000019960.
GeneIDi293494.
KEGGirno:293494.
UCSCiRGD:1359572. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079045 mRNA. Translation: AAH79045.1.
RefSeqiNP_001013922.1. NM_001013900.1.
UniGeneiRn.3179.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027034.

Proteomic databases

PaxDbiQ6AYH2.
PRIDEiQ6AYH2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000027033; ENSRNOP00000027034; ENSRNOG00000019960.
GeneIDi293494.
KEGGirno:293494.
UCSCiRGD:1359572. rat.

Organism-specific databases

CTDi283899.
RGDi1359572. Ino80e.

Phylogenomic databases

eggNOGiENOG410IIN3. Eukaryota.
ENOG4111S1J. LUCA.
GeneTreeiENSGT00390000011918.
HOGENOMiHOG000047138.
HOVERGENiHBG063770.
InParanoidiQ6AYH2.
KOiK11669.
OMAiMPPHTIL.
OrthoDBiEOG7034J4.
PhylomeDBiQ6AYH2.
TreeFamiTF326931.

Enzyme and pathway databases

ReactomeiR-RNO-5696394. DNA Damage Recognition in GG-NER.

Miscellaneous databases

PROiQ6AYH2.

Gene expression databases

GenevisibleiQ6AYH2. RN.

Family and domain databases

InterProiIPR026678. INO80E.
[Graphical view]
PANTHERiPTHR21812. PTHR21812. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiIN80E_RAT
AccessioniPrimary (citable) accession number: Q6AYH2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: September 13, 2004
Last modified: June 8, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.