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Protein

INO80 complex subunit E

Gene

Ino80e

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.By similarity

GO - Biological processi

Keywordsi

Biological processDNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-RNO-5689603. UCH proteinases.
R-RNO-5696394. DNA Damage Recognition in GG-NER.

Names & Taxonomyi

Protein namesi
Recommended name:
INO80 complex subunit E
Alternative name(s):
Coiled-coil domain-containing protein 95
Gene namesi
Name:Ino80e
Synonyms:Ccdc95
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1359572. Ino80e.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002342931 – 244INO80 complex subunit EAdd BLAST244

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki159Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki171Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiQ6AYH2.
PRIDEiQ6AYH2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000019960.
GenevisibleiQ6AYH2. RN.

Interactioni

Subunit structurei

Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027034.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili10 – 54Sequence analysisAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi91 – 210Pro-richAdd BLAST120

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IIN3. Eukaryota.
ENOG4111S1J. LUCA.
GeneTreeiENSGT00390000011918.
HOGENOMiHOG000047138.
HOVERGENiHBG063770.
InParanoidiQ6AYH2.
KOiK11669.
OMAiFPPEYLA.
OrthoDBiEOG091G0WUF.
PhylomeDBiQ6AYH2.
TreeFamiTF326931.

Family and domain databases

InterProiView protein in InterPro
IPR026678. INO80E.
PANTHERiPTHR21812. PTHR21812. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AYH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGPADGEVD YKKKYRNLKR KLKFLIYEHE CFQEELRKAQ RKLLKVSRDK
60 70 80 90 100
SFLLDRLLQY ENVDEDSSDS DATASSDNSE TEGTPKLSDT PAPKRKRSPP
110 120 130 140 150
MGGAPSPSSL SLPPSSGFPL QTSGAPSPYL SSLASPPYPP FPSDYLALQL
160 170 180 190 200
PEPSPLRPKL EKRPRLPRKL KMAVGPPDCP VGGPLAFPAR GSGASVGAAL
210 220 230 240
TPLPPPKMPP HTILSTVPQQ MFSDAGSGDD ALDGDDDLVI DIPE
Length:244
Mass (Da):26,358
Last modified:September 13, 2004 - v1
Checksum:iA28776CEC894E0F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079045 mRNA. Translation: AAH79045.1.
RefSeqiNP_001013922.1. NM_001013900.1.
UniGeneiRn.3179.

Genome annotation databases

EnsembliENSRNOT00000027033; ENSRNOP00000027034; ENSRNOG00000019960.
GeneIDi293494.
KEGGirno:293494.
UCSCiRGD:1359572. rat.

Similar proteinsi

Entry informationi

Entry nameiIN80E_RAT
AccessioniPrimary (citable) accession number: Q6AYH2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: September 13, 2004
Last modified: August 30, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome