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Q6AYF6 (GL8D1_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycosyltransferase 8 domain-containing protein 1

EC=2.4.1.-
Gene names
Name:Glt8d1
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass type II membrane protein Potential.

Sequence similarities

Belongs to the glycosyltransferase 8 family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   Molecular functionGlycosyltransferase
Transferase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiontransferase activity, transferring glycosyl groups

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 371371Glycosyltransferase 8 domain-containing protein 1
PRO_0000288530

Regions

Topological domain1 – 55Cytoplasmic Potential
Transmembrane6 – 2621Helical; Signal-anchor for type II membrane protein; Potential
Topological domain27 – 371345Lumenal Potential

Amino acid modifications

Glycosylation2571N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q6AYF6 [UniParc].

Last modified September 13, 2004. Version 1.
Checksum: 7C56790EF66FE4EF

FASTA37142,135
        10         20         30         40         50         60 
MSFRKVTIII WALAVILFLL ALHHNFLSLS SLLRNDVSDS GIVGLQPIDF TANFHQHPVN 

        70         80         90        100        110        120 
ERQEEIPVVI AASEDRLGGT IAAINSIHQN TRSNVIFYIV TFNRTADHLR SWLNSGSLKS 

       130        140        150        160        170        180 
IRYKIVNFDT KLLEGKVKED PDQGESMKPL TFARFYLPIL VPSAKKAIYM DDDVIVQGDI 

       190        200        210        220        230        240 
LALYNTPLKP GHAAAFSEDC DSASTKVMIR GAGNQYNYIG YLDYKKERIR KLSMKASTCS 

       250        260        270        280        290        300 
FNPGVFVANL TEWKRQNVTN QLEKWMKLNV EEGLYSRTLA GSITTPPLLI VFYQQHSTID 

       310        320        330        340        350        360 
PMWNVRHLGS SAGKRYSPQF VKAAKLLHWN GHFKPWGRAA SYADVWEKWY IPDPTGKFSL 

       370 
IRRHMDTSNI K 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Lung.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC079066 mRNA. Translation: AAH79066.1.
RefSeqNP_001007684.1. NM_001007683.1.
UniGeneRn.91636.

3D structure databases

ProteinModelPortalQ6AYF6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000024624.

Proteomic databases

PaxDbQ6AYF6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000013291; ENSRNOP00000013291; ENSRNOG00000018179.
GeneID306253.
KEGGrno:306253.
UCSCRGD:1359293. rat.

Organism-specific databases

CTD55830.
RGD1359293. Glt8d1.

Phylogenomic databases

eggNOGNOG74598.
GeneTreeENSGT00390000016670.
HOGENOMHOG000112730.
HOVERGENHBG055240.
OrthoDBEOG7RBZ8R.

Gene expression databases

GenevestigatorQ6AYF6.

Family and domain databases

Gene3D3.90.550.10. 1 hit.
InterProIPR002495. Glyco_trans_8.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamPF01501. Glyco_transf_8. 1 hit.
[Graphical view]
SUPFAMSSF53448. SSF53448. 1 hit.
ProtoNetSearch...

Other

NextBio655689.

Entry information

Entry nameGL8D1_RAT
AccessionPrimary (citable) accession number: Q6AYF6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: September 13, 2004
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families