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Protein

Glycosyltransferase 8 domain-containing protein 1

Gene

Glt8d1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. transferase activity, transferring glycosyl groups Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glycosyltransferase 8 domain-containing protein 1 (EC:2.4.1.-)
Gene namesi
Name:Glt8d1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 16

Organism-specific databases

RGDi1359293. Glt8d1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 55CytoplasmicSequence Analysis
Transmembranei6 – 2621Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST
Topological domaini27 – 371345LumenalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 371371Glycosyltransferase 8 domain-containing protein 1PRO_0000288530Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi257 – 2571N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ6AYF6.

Expressioni

Gene expression databases

ExpressionAtlasiQ6AYF6. baseline.
GenevestigatoriQ6AYF6.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000024624.

Structurei

3D structure databases

ProteinModelPortaliQ6AYF6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 8 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG74598.
GeneTreeiENSGT00390000016670.
HOGENOMiHOG000112730.
HOVERGENiHBG055240.
InParanoidiQ6AYF6.
OrthoDBiEOG7RBZ8R.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR002495. Glyco_trans_8.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF01501. Glyco_transf_8. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AYF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFRKVTIII WALAVILFLL ALHHNFLSLS SLLRNDVSDS GIVGLQPIDF
60 70 80 90 100
TANFHQHPVN ERQEEIPVVI AASEDRLGGT IAAINSIHQN TRSNVIFYIV
110 120 130 140 150
TFNRTADHLR SWLNSGSLKS IRYKIVNFDT KLLEGKVKED PDQGESMKPL
160 170 180 190 200
TFARFYLPIL VPSAKKAIYM DDDVIVQGDI LALYNTPLKP GHAAAFSEDC
210 220 230 240 250
DSASTKVMIR GAGNQYNYIG YLDYKKERIR KLSMKASTCS FNPGVFVANL
260 270 280 290 300
TEWKRQNVTN QLEKWMKLNV EEGLYSRTLA GSITTPPLLI VFYQQHSTID
310 320 330 340 350
PMWNVRHLGS SAGKRYSPQF VKAAKLLHWN GHFKPWGRAA SYADVWEKWY
360 370
IPDPTGKFSL IRRHMDTSNI K
Length:371
Mass (Da):42,135
Last modified:September 13, 2004 - v1
Checksum:i7C56790EF66FE4EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079066 mRNA. Translation: AAH79066.1.
RefSeqiNP_001007684.1. NM_001007683.1.
UniGeneiRn.91636.

Genome annotation databases

EnsembliENSRNOT00000013291; ENSRNOP00000013291; ENSRNOG00000018179.
GeneIDi306253.
KEGGirno:306253.
UCSCiRGD:1359293. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079066 mRNA. Translation: AAH79066.1.
RefSeqiNP_001007684.1. NM_001007683.1.
UniGeneiRn.91636.

3D structure databases

ProteinModelPortaliQ6AYF6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000024624.

Proteomic databases

PaxDbiQ6AYF6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000013291; ENSRNOP00000013291; ENSRNOG00000018179.
GeneIDi306253.
KEGGirno:306253.
UCSCiRGD:1359293. rat.

Organism-specific databases

CTDi55830.
RGDi1359293. Glt8d1.

Phylogenomic databases

eggNOGiNOG74598.
GeneTreeiENSGT00390000016670.
HOGENOMiHOG000112730.
HOVERGENiHBG055240.
InParanoidiQ6AYF6.
OrthoDBiEOG7RBZ8R.

Miscellaneous databases

NextBioi655689.

Gene expression databases

ExpressionAtlasiQ6AYF6. baseline.
GenevestigatoriQ6AYF6.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR002495. Glyco_trans_8.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF01501. Glyco_transf_8. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Lung.

Entry informationi

Entry nameiGL8D1_RAT
AccessioniPrimary (citable) accession number: Q6AYF6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: September 13, 2004
Last modified: January 7, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.