Reviewed,
UniProtKB/Swiss-Prot Q6AXY0 (GSTA6_RAT)
Last modified
November 3, 2009.
Version 50.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Glutathione S-transferase A6 EC=2.5.1.18 Alternative name(s): GST class-alpha member 6 | ||
| Gene names |
| ||
| Organism | Rattus norvegicus (Rat) | ||
| Taxonomic identifier | 10116 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus |
Protein attributes
| Sequence length | 222 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity. |
| Catalytic activity | RX + glutathione = HX + R-S-glutathione. |
| Subunit structure | Homodimer or heterodimer of GSTA1 and GSTA2 By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the GST superfamily. Alpha family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Molecular function | Transferase |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | metabolic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | glutathione transferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis. |
| [2] | Lubec G., Afjehi-Sadat L., Chen W.-Q. Submitted (APR-2007) to UniProtKB Cited for: PROTEIN SEQUENCE OF 21-33 AND 139-152, MASS SPECTROMETRY. Strain: Sprague-Dawley. Tissue: Hippocampus and Spinal cord. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| BC079271 mRNA. Translation: AAH79271.1. | |
| IPI | IPI00391161. |
| RefSeq | NP_001019532.1. |
| UniGene | Rn.33233 |
3D structure databases | |
| SMR | Q6AXY0. Positions 2-222. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q6AXY0. |
Genome annotation databases | |
| Ensembl | ENSRNOT00000036813; ENSRNOP00000031201; ENSRNOG00000033402; Rattus norvegicus. [Genome view] |
| GeneID | 501110. |
| KEGG | rno:501110. |
| NMPDR | fig|10116.3.peg.29794. |
| UCSC | NM_001024361. rat. |
Organism-specific databases | |
| RGD | 1565402. LOC501110. |
Phylogenomic databases | |
| HOVERGEN | Q6AXY0. |
| OMA | YNMEELD. |
Enzyme and pathway databases | |
| BRENDA | 2.5.1.18. 248. |
Gene expression databases | |
| Genevestigator | Q6AXY0. |
Family and domain databases | |
| InterPro | IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR003080. GST_alpha. IPR004046. GST_C. IPR012335. Thioredoxin_fold. [Graphical view] |
| Gene3D | G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. |
| PANTHER | PTHR11571:SF4. GST_alpha. 1 hit. |
| Pfam | PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view] |
| PRINTS | PR01266. GSTRNSFRASEA. |
| PROSITE | PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 708316. |
Entry information
| Entry name | GSTA6_RAT | ||||||||
| Accession | Primary (citable) accession number: Q6AXY0 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||

Clusters with


