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Protein

Outer dense fiber protein 4

Gene

Odf4

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Outer dense fiber protein 4
Alternative name(s):
Outer dense fiber of sperm tails protein 4
Gene namesi
Name:Odf4
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1359332. Odf4.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Transmembranei201 – 221HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003047241 – 290Outer dense fiber protein 4Add BLAST290

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei28PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6AXT9.
PRIDEiQ6AXT9.

Expressioni

Gene expression databases

BgeeiENSRNOG00000004225.
GenevisibleiQ6AXT9. RN.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi57 – 61Poly-Leu5
Compositional biasi235 – 238Poly-Ser4

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IZV4. Eukaryota.
ENOG4111BHV. LUCA.
GeneTreeiENSGT00390000003542.
HOGENOMiHOG000115258.
HOVERGENiHBG097511.
InParanoidiQ6AXT9.
OMAiFTIWLHL.
OrthoDBiEOG091G0NXG.
PhylomeDBiQ6AXT9.

Family and domain databases

InterProiIPR004031. PMP22/EMP/MP20/Claudin.
[Graphical view]
PfamiPF00822. PMP22_Claudin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6AXT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESDLTVEES ETIKTRSRRP LTEHRRHSLL PLQWKLAHSS RWMAQVVASE
60 70 80 90 100
FSLLAFLLLL LMVFSKKWLY PSKSRFHQRY PQNITKRVYT SIHSMSTGLL
110 120 130 140 150
YICISKSCLS SDNEEDNFKM WTIHPAFGVA KISFILAVGL GFVLTVWLHL
160 170 180 190 200
PYLPCLQRMP FFGLIGIILS FCEVTLIFLT LLLFPVNLWI YELKKNISVP
210 220 230 240 250
IGWSYFIGWL VLILYLTCGI LCYLNHKNFW SLIMSSSSIN ATCSSSVPVS
260 270 280 290
LMNTSQISKS QADILDPTQD DQKPLSSDNI ALPPNPDTTD
Length:290
Mass (Da):33,146
Last modified:September 13, 2004 - v1
Checksum:i4BC2A51749650BB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079319 mRNA. Translation: AAH79319.1.
RefSeqiNP_001007671.1. NM_001007670.1.
UniGeneiRn.137152.

Genome annotation databases

EnsembliENSRNOT00000005667; ENSRNOP00000005667; ENSRNOG00000004225.
GeneIDi303236.
KEGGirno:303236.
UCSCiRGD:1359332. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079319 mRNA. Translation: AAH79319.1.
RefSeqiNP_001007671.1. NM_001007670.1.
UniGeneiRn.137152.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ6AXT9.
PRIDEiQ6AXT9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000005667; ENSRNOP00000005667; ENSRNOG00000004225.
GeneIDi303236.
KEGGirno:303236.
UCSCiRGD:1359332. rat.

Organism-specific databases

CTDi146852.
RGDi1359332. Odf4.

Phylogenomic databases

eggNOGiENOG410IZV4. Eukaryota.
ENOG4111BHV. LUCA.
GeneTreeiENSGT00390000003542.
HOGENOMiHOG000115258.
HOVERGENiHBG097511.
InParanoidiQ6AXT9.
OMAiFTIWLHL.
OrthoDBiEOG091G0NXG.
PhylomeDBiQ6AXT9.

Miscellaneous databases

PROiQ6AXT9.

Gene expression databases

BgeeiENSRNOG00000004225.
GenevisibleiQ6AXT9. RN.

Family and domain databases

InterProiIPR004031. PMP22/EMP/MP20/Claudin.
[Graphical view]
PfamiPF00822. PMP22_Claudin. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiODFP4_RAT
AccessioniPrimary (citable) accession number: Q6AXT9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 13, 2004
Last modified: September 7, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.