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Protein

Tubulin polyglutamylase complex subunit 2

Gene

Tpgs2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin polyglutamylase complex subunit 2
Short name:
PGs2
Gene namesi
Name:Tpgs2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1310571. Tpgs2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 296296Tubulin polyglutamylase complex subunit 2PRO_0000079306Add
BLAST

Proteomic databases

PaxDbiQ6AXS8.
PRIDEiQ6AXS8.

Interactioni

Subunit structurei

Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1.By similarity

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IJVC. Eukaryota.
ENOG4111HTQ. LUCA.
HOGENOMiHOG000294114.
HOVERGENiHBG073636.
InParanoidiQ6AXS8.
KOiK16605.
PhylomeDBiQ6AXS8.

Family and domain databases

InterProiIPR018958. SMI1/KNR4-like_dom.
[Graphical view]
SMARTiSM00860. SMI1_KNR4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6AXS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEETPPPMQA GSKPHLEKLT LGVTRILESS PGVTEVSIIE KLPAERHMIS
60 70 80 90 100
SWEQKNNCVM PEDVRNFYLM TNGFHMTWSV KLDDHIIPLG SMVINGISKL
110 120 130 140 150
TQLIQSSVYS LPNAPTLADL EDDSQEGNED HQLEKPHFDC RSAIFELDSC
160 170 180 190 200
GGNGKVCLVY KNGKPGLAHD TEIWFLDRAL YWHFLTDTFT AYYRLLITHL
210 220 230 240 250
GLPQWQYAFT SYGISPQAKQ WFSMYKPITY NTSLLTEEPD TFVNKLDPSK
260 270 280 290
VFKSKNKILI PKKKGPVQPV SGQKGPGPLA PPTSKPSAGC GNPVRK
Length:296
Mass (Da):33,163
Last modified:September 5, 2006 - v2
Checksum:iC7F56E1D5661B578
GO

Sequence cautioni

The sequence AAH79332.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079332 mRNA. Translation: AAH79332.1. Different initiation.
RefSeqiNP_001014169.2. NM_001014147.1.
UniGeneiRn.54973.

Genome annotation databases

GeneIDi361301.
KEGGirno:361301.
UCSCiRGD:1310571. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079332 mRNA. Translation: AAH79332.1. Different initiation.
RefSeqiNP_001014169.2. NM_001014147.1.
UniGeneiRn.54973.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ6AXS8.
PRIDEiQ6AXS8.

Protocols and materials databases

DNASUi361301.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi361301.
KEGGirno:361301.
UCSCiRGD:1310571. rat.

Organism-specific databases

CTDi25941.
RGDi1310571. Tpgs2.

Phylogenomic databases

eggNOGiENOG410IJVC. Eukaryota.
ENOG4111HTQ. LUCA.
HOGENOMiHOG000294114.
HOVERGENiHBG073636.
InParanoidiQ6AXS8.
KOiK16605.
PhylomeDBiQ6AXS8.

Miscellaneous databases

PROiQ6AXS8.

Family and domain databases

InterProiIPR018958. SMI1/KNR4-like_dom.
[Graphical view]
SMARTiSM00860. SMI1_KNR4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Lung.

Entry informationi

Entry nameiTPGS2_RAT
AccessioniPrimary (citable) accession number: Q6AXS8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: September 5, 2006
Last modified: June 8, 2016
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.