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Q6AXR5

- S35A3_RAT

UniProt

Q6AXR5 - S35A3_RAT

Protein

UDP-N-acetylglucosamine transporter

Gene

Slc35a3

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 1 (13 Sep 2004)
      Previous versions | rss
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    Functioni

    Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides By similarity.By similarity

    GO - Molecular functioni

    1. nucleotide-sugar transmembrane transporter activity Source: InterPro
    2. sugar:proton symporter activity Source: InterPro

    GO - Biological processi

    1. UDP-N-acetylglucosamine transport Source: UniProtKB

    Keywords - Biological processi

    Sugar transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UDP-N-acetylglucosamine transporter
    Alternative name(s):
    Golgi UDP-GlcNAc transporter
    Solute carrier family 35 member A3
    Gene namesi
    Name:Slc35a3
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Unplaced

    Organism-specific databases

    RGDi1308615. Slc35a3.

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi membrane Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 326326UDP-N-acetylglucosamine transporterPRO_0000213359Add
    BLAST

    Proteomic databases

    PaxDbiQ6AXR5.
    PRIDEiQ6AXR5.

    Expressioni

    Gene expression databases

    GenevestigatoriQ6AXR5.

    Interactioni

    Subunit structurei

    Interacts with SLC35A2.By similarity

    Protein-protein interaction databases

    MINTiMINT-4572437.
    STRINGi10116.ENSRNOP00000021676.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei4 – 2421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei38 – 5821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei136 – 15621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei174 – 19421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei212 – 23221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei243 – 26321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei269 – 28921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei293 – 31321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0697.
    HOGENOMiHOG000216649.
    HOVERGENiHBG054025.
    InParanoidiQ6AXR5.
    KOiK15272.
    OrthoDBiEOG7NCV4D.
    PhylomeDBiQ6AXR5.
    TreeFamiTF315345.

    Family and domain databases

    InterProiIPR007271. Nuc_sug_transpt.
    IPR021189. UDP/CMP-sugar_transptr.
    IPR004689. UDPgal_transpt.
    [Graphical view]
    PANTHERiPTHR10231. PTHR10231. 1 hit.
    PfamiPF04142. Nuc_sug_transp. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005799. UDP-gal_transpt. 1 hit.
    TIGRFAMsiTIGR00803. nst. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6AXR5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSANLKYLSL GILVFQTTSL VLTMRYSRTL KEEGPRYLSS TAVVVAEFLK    50
    IMACIFLVYK DSKCSVRTLN RVLHDEILNK PMETLKLAIP SGIYTLQNNL 100
    LYVALSNLDA ATYQVTYQLK ILTTALFSVS MLGKKLGMYQ WLSLVILMAG 150
    VAFVQWPSDS QELNSKDLST GSQFVGLMAV LIACFSSGFA GVYFEKILKE 200
    TKQSVWIRNI QLGFFGSIFG LMGVYVYDGE LVSKNGFFQG YNQLTWIVVV 250
    LQALGGLVIA AVIKYADNIL KGFATSLSII LSTIISYFWL QDFVPTSVFF 300
    LGAILVIAAT FLYGYDPKPA GNPTKA 326
    Length:326
    Mass (Da):36,079
    Last modified:September 13, 2004 - v1
    Checksum:i4C1BB88723E59C24
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC079371 mRNA. Translation: AAH79371.1.
    RefSeqiNP_001012082.1. NM_001012082.1.
    UniGeneiRn.162630.

    Genome annotation databases

    GeneIDi310808.
    KEGGirno:310808.
    UCSCiRGD:1308615. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC079371 mRNA. Translation: AAH79371.1 .
    RefSeqi NP_001012082.1. NM_001012082.1.
    UniGenei Rn.162630.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-4572437.
    STRINGi 10116.ENSRNOP00000021676.

    Proteomic databases

    PaxDbi Q6AXR5.
    PRIDEi Q6AXR5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 310808.
    KEGGi rno:310808.
    UCSCi RGD:1308615. rat.

    Organism-specific databases

    CTDi 23443.
    RGDi 1308615. Slc35a3.

    Phylogenomic databases

    eggNOGi COG0697.
    HOGENOMi HOG000216649.
    HOVERGENi HBG054025.
    InParanoidi Q6AXR5.
    KOi K15272.
    OrthoDBi EOG7NCV4D.
    PhylomeDBi Q6AXR5.
    TreeFami TF315345.

    Miscellaneous databases

    NextBioi 662681.
    PROi Q6AXR5.

    Gene expression databases

    Genevestigatori Q6AXR5.

    Family and domain databases

    InterProi IPR007271. Nuc_sug_transpt.
    IPR021189. UDP/CMP-sugar_transptr.
    IPR004689. UDPgal_transpt.
    [Graphical view ]
    PANTHERi PTHR10231. PTHR10231. 1 hit.
    Pfami PF04142. Nuc_sug_transp. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005799. UDP-gal_transpt. 1 hit.
    TIGRFAMsi TIGR00803. nst. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Kidney.

    Entry informationi

    Entry nameiS35A3_RAT
    AccessioniPrimary (citable) accession number: Q6AXR5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 15, 2005
    Last sequence update: September 13, 2004
    Last modified: October 1, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3