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Protein

UDP-N-acetylglucosamine transporter

Gene

Slc35a3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

ReactomeiR-RNO-727802. Transport of nucleotide sugars.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine transporter
Alternative name(s):
Golgi UDP-GlcNAc transporter
Solute carrier family 35 member A3
Gene namesi
Name:Slc35a3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1308615. Slc35a3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei38 – 58HelicalSequence analysisAdd BLAST21
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Transmembranei212 – 232HelicalSequence analysisAdd BLAST21
Transmembranei243 – 263HelicalSequence analysisAdd BLAST21
Transmembranei269 – 289HelicalSequence analysisAdd BLAST21
Transmembranei293 – 313HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002133591 – 326UDP-N-acetylglucosamine transporterAdd BLAST326

Proteomic databases

PRIDEiQ6AXR5.

Expressioni

Gene expression databases

GenevisibleiQ6AXR5. RN.

Interactioni

Subunit structurei

Interacts with SLC35A2.By similarity

Protein-protein interaction databases

MINTiMINT-4572437.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00550000074563.
HOGENOMiHOG000216649.
HOVERGENiHBG054025.
InParanoidiQ6AXR5.
KOiK15272.
OMAiNWAVWST.
OrthoDBiEOG091G0CHS.
PhylomeDBiQ6AXR5.
TreeFamiTF315345.

Family and domain databases

InterProiIPR007271. Nuc_sug_transpt.
[Graphical view]
PANTHERiPTHR10231. PTHR10231. 1 hit.
PfamiPF04142. Nuc_sug_transp. 1 hit.
[Graphical view]
PIRSFiPIRSF005799. UDP-gal_transpt. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AXR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSANLKYLSL GILVFQTTSL VLTMRYSRTL KEEGPRYLSS TAVVVAEFLK
60 70 80 90 100
IMACIFLVYK DSKCSVRTLN RVLHDEILNK PMETLKLAIP SGIYTLQNNL
110 120 130 140 150
LYVALSNLDA ATYQVTYQLK ILTTALFSVS MLGKKLGMYQ WLSLVILMAG
160 170 180 190 200
VAFVQWPSDS QELNSKDLST GSQFVGLMAV LIACFSSGFA GVYFEKILKE
210 220 230 240 250
TKQSVWIRNI QLGFFGSIFG LMGVYVYDGE LVSKNGFFQG YNQLTWIVVV
260 270 280 290 300
LQALGGLVIA AVIKYADNIL KGFATSLSII LSTIISYFWL QDFVPTSVFF
310 320
LGAILVIAAT FLYGYDPKPA GNPTKA
Length:326
Mass (Da):36,079
Last modified:September 13, 2004 - v1
Checksum:i4C1BB88723E59C24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079371 mRNA. Translation: AAH79371.1.
RefSeqiNP_001012082.1. NM_001012082.1.
UniGeneiRn.162630.

Genome annotation databases

EnsembliENSRNOT00000085122; ENSRNOP00000074264; ENSRNOG00000061832.
GeneIDi310808.
KEGGirno:310808.
UCSCiRGD:1308615. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079371 mRNA. Translation: AAH79371.1.
RefSeqiNP_001012082.1. NM_001012082.1.
UniGeneiRn.162630.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4572437.

Proteomic databases

PRIDEiQ6AXR5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000085122; ENSRNOP00000074264; ENSRNOG00000061832.
GeneIDi310808.
KEGGirno:310808.
UCSCiRGD:1308615. rat.

Organism-specific databases

CTDi23443.
RGDi1308615. Slc35a3.

Phylogenomic databases

GeneTreeiENSGT00550000074563.
HOGENOMiHOG000216649.
HOVERGENiHBG054025.
InParanoidiQ6AXR5.
KOiK15272.
OMAiNWAVWST.
OrthoDBiEOG091G0CHS.
PhylomeDBiQ6AXR5.
TreeFamiTF315345.

Enzyme and pathway databases

ReactomeiR-RNO-727802. Transport of nucleotide sugars.

Miscellaneous databases

PROiQ6AXR5.

Gene expression databases

GenevisibleiQ6AXR5. RN.

Family and domain databases

InterProiIPR007271. Nuc_sug_transpt.
[Graphical view]
PANTHERiPTHR10231. PTHR10231. 1 hit.
PfamiPF04142. Nuc_sug_transp. 1 hit.
[Graphical view]
PIRSFiPIRSF005799. UDP-gal_transpt. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiS35A3_RAT
AccessioniPrimary (citable) accession number: Q6AXR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: September 13, 2004
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.