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Protein

UDP-N-acetylglucosamine transporter

Gene

Slc35a3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine transporter
Alternative name(s):
Golgi UDP-GlcNAc transporter
Solute carrier family 35 member A3
Gene namesi
Name:Slc35a3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1308615. Slc35a3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei4 – 2421HelicalSequence AnalysisAdd
BLAST
Transmembranei38 – 5821HelicalSequence AnalysisAdd
BLAST
Transmembranei136 – 15621HelicalSequence AnalysisAdd
BLAST
Transmembranei174 – 19421HelicalSequence AnalysisAdd
BLAST
Transmembranei212 – 23221HelicalSequence AnalysisAdd
BLAST
Transmembranei243 – 26321HelicalSequence AnalysisAdd
BLAST
Transmembranei269 – 28921HelicalSequence AnalysisAdd
BLAST
Transmembranei293 – 31321HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 326326UDP-N-acetylglucosamine transporterPRO_0000213359Add
BLAST

Proteomic databases

PaxDbiQ6AXR5.
PRIDEiQ6AXR5.

Expressioni

Gene expression databases

GenevisibleiQ6AXR5. RN.

Interactioni

Subunit structurei

Interacts with SLC35A2.By similarity

Protein-protein interaction databases

MINTiMINT-4572437.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0697.
GeneTreeiENSGT00550000074563.
HOGENOMiHOG000216649.
HOVERGENiHBG054025.
InParanoidiQ6AXR5.
KOiK15272.
OrthoDBiEOG7NCV4D.
PhylomeDBiQ6AXR5.
TreeFamiTF315345.

Family and domain databases

InterProiIPR007271. Nuc_sug_transpt.
IPR021189. UDP/CMP-sugar_transptr.
IPR004689. UDPgal_transpt.
[Graphical view]
PANTHERiPTHR10231. PTHR10231. 1 hit.
PfamiPF04142. Nuc_sug_transp. 1 hit.
[Graphical view]
PIRSFiPIRSF005799. UDP-gal_transpt. 1 hit.
TIGRFAMsiTIGR00803. nst. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AXR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSANLKYLSL GILVFQTTSL VLTMRYSRTL KEEGPRYLSS TAVVVAEFLK
60 70 80 90 100
IMACIFLVYK DSKCSVRTLN RVLHDEILNK PMETLKLAIP SGIYTLQNNL
110 120 130 140 150
LYVALSNLDA ATYQVTYQLK ILTTALFSVS MLGKKLGMYQ WLSLVILMAG
160 170 180 190 200
VAFVQWPSDS QELNSKDLST GSQFVGLMAV LIACFSSGFA GVYFEKILKE
210 220 230 240 250
TKQSVWIRNI QLGFFGSIFG LMGVYVYDGE LVSKNGFFQG YNQLTWIVVV
260 270 280 290 300
LQALGGLVIA AVIKYADNIL KGFATSLSII LSTIISYFWL QDFVPTSVFF
310 320
LGAILVIAAT FLYGYDPKPA GNPTKA
Length:326
Mass (Da):36,079
Last modified:September 13, 2004 - v1
Checksum:i4C1BB88723E59C24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079371 mRNA. Translation: AAH79371.1.
RefSeqiNP_001012082.1. NM_001012082.1.
UniGeneiRn.162630.

Genome annotation databases

EnsembliENSRNOT00000085122; ENSRNOP00000074264; ENSRNOG00000061832.
GeneIDi310808.
KEGGirno:310808.
UCSCiRGD:1308615. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079371 mRNA. Translation: AAH79371.1.
RefSeqiNP_001012082.1. NM_001012082.1.
UniGeneiRn.162630.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4572437.

Proteomic databases

PaxDbiQ6AXR5.
PRIDEiQ6AXR5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000085122; ENSRNOP00000074264; ENSRNOG00000061832.
GeneIDi310808.
KEGGirno:310808.
UCSCiRGD:1308615. rat.

Organism-specific databases

CTDi23443.
RGDi1308615. Slc35a3.

Phylogenomic databases

eggNOGiCOG0697.
GeneTreeiENSGT00550000074563.
HOGENOMiHOG000216649.
HOVERGENiHBG054025.
InParanoidiQ6AXR5.
KOiK15272.
OrthoDBiEOG7NCV4D.
PhylomeDBiQ6AXR5.
TreeFamiTF315345.

Miscellaneous databases

NextBioi662681.
PROiQ6AXR5.

Gene expression databases

GenevisibleiQ6AXR5. RN.

Family and domain databases

InterProiIPR007271. Nuc_sug_transpt.
IPR021189. UDP/CMP-sugar_transptr.
IPR004689. UDPgal_transpt.
[Graphical view]
PANTHERiPTHR10231. PTHR10231. 1 hit.
PfamiPF04142. Nuc_sug_transp. 1 hit.
[Graphical view]
PIRSFiPIRSF005799. UDP-gal_transpt. 1 hit.
TIGRFAMsiTIGR00803. nst. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.

Entry informationi

Entry nameiS35A3_RAT
AccessioniPrimary (citable) accession number: Q6AXR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: September 13, 2004
Last modified: July 22, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.