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Protein

UDP-N-acetylglucosamine transporter

Gene

Slc35a3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

ReactomeiR-RNO-727802 Transport of nucleotide sugars

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine transporter
Alternative name(s):
Golgi UDP-GlcNAc transporter
Solute carrier family 35 member A3
Gene namesi
Name:Slc35a3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1308615 Slc35a3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei38 – 58HelicalSequence analysisAdd BLAST21
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Transmembranei212 – 232HelicalSequence analysisAdd BLAST21
Transmembranei243 – 263HelicalSequence analysisAdd BLAST21
Transmembranei269 – 289HelicalSequence analysisAdd BLAST21
Transmembranei293 – 313HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002133591 – 326UDP-N-acetylglucosamine transporterAdd BLAST326

Proteomic databases

PRIDEiQ6AXR5

Expressioni

Gene expression databases

BgeeiENSRNOG00000061832
GenevisibleiQ6AXR5 RN

Interactioni

Subunit structurei

Interacts with SLC35A2.By similarity

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00550000074563
HOGENOMiHOG000216649
HOVERGENiHBG054025
InParanoidiQ6AXR5
KOiK15272
OMAiEHSAGSQ
OrthoDBiEOG091G0CHS
PhylomeDBiQ6AXR5
TreeFamiTF315345

Family and domain databases

InterProiView protein in InterPro
IPR007271 Nuc_sug_transpt
PANTHERiPTHR10231 PTHR10231, 1 hit
PfamiView protein in Pfam
PF04142 Nuc_sug_transp, 1 hit
PIRSFiPIRSF005799 UDP-gal_transpt, 1 hit

Sequencei

Sequence statusi: Complete.

Q6AXR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSANLKYLSL GILVFQTTSL VLTMRYSRTL KEEGPRYLSS TAVVVAEFLK
60 70 80 90 100
IMACIFLVYK DSKCSVRTLN RVLHDEILNK PMETLKLAIP SGIYTLQNNL
110 120 130 140 150
LYVALSNLDA ATYQVTYQLK ILTTALFSVS MLGKKLGMYQ WLSLVILMAG
160 170 180 190 200
VAFVQWPSDS QELNSKDLST GSQFVGLMAV LIACFSSGFA GVYFEKILKE
210 220 230 240 250
TKQSVWIRNI QLGFFGSIFG LMGVYVYDGE LVSKNGFFQG YNQLTWIVVV
260 270 280 290 300
LQALGGLVIA AVIKYADNIL KGFATSLSII LSTIISYFWL QDFVPTSVFF
310 320
LGAILVIAAT FLYGYDPKPA GNPTKA
Length:326
Mass (Da):36,079
Last modified:September 13, 2004 - v1
Checksum:i4C1BB88723E59C24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079371 mRNA Translation: AAH79371.1
RefSeqiNP_001012082.1, NM_001012082.1
UniGeneiRn.162630

Genome annotation databases

EnsembliENSRNOT00000085122; ENSRNOP00000074264; ENSRNOG00000061832
GeneIDi310808
KEGGirno:310808
UCSCiRGD:1308615 rat

Similar proteinsi

Entry informationi

Entry nameiS35A3_RAT
AccessioniPrimary (citable) accession number: Q6AXR5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: September 13, 2004
Last modified: April 25, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome