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Protein

Meiosis-specific nuclear structural protein 1

Gene

Mns1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Meiosis

Names & Taxonomyi

Protein namesi
Recommended name:
Meiosis-specific nuclear structural protein 1
Gene namesi
Name:Mns1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1549718. Mns1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 498498Meiosis-specific nuclear structural protein 1PRO_0000298924Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei188 – 1881PhosphotyrosineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6AXQ8.
PRIDEiQ6AXQ8.

Expressioni

Gene expression databases

GenevisibleiQ6AXQ8. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000007941.

Structurei

3D structure databases

ProteinModelPortaliQ6AXQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili29 – 253225Sequence analysisAdd
BLAST
Coiled coili287 – 36074Sequence analysisAdd
BLAST
Coiled coili390 – 43748Sequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi46 – 447402Glu-richAdd
BLAST

Sequence similaritiesi

Belongs to the MNS1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IFU7. Eukaryota.
ENOG410YXPQ. LUCA.
GeneTreeiENSGT00730000111210.
HOGENOMiHOG000006500.
HOVERGENiHBG108140.
InParanoidiQ6AXQ8.
OMAiGCINEII.
OrthoDBiEOG7D59P3.
PhylomeDBiQ6AXQ8.
TreeFamiTF329219.

Family and domain databases

InterProiIPR026504. MNS1.
[Graphical view]
PANTHERiPTHR19265:SF0. PTHR19265:SF0. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AXQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANKKRAMSF SEKHQQLVDE NFRKSLHVQV LNKLERQAKN QVVQNENDER
60 70 80 90 100
VERQRFLRVL QNEQFELDME EAVQKAEENK RMRDRQLEQE ERLANELARL
110 120 130 140 150
KHESLKDEKM RQQVRENSIE LRELEQKLKA AYMNKERAAQ IVEKDVIKYE
160 170 180 190 200
QMKRDAEIER IMMEEHKRLL KEENVKQEKR DKERAQYYVD LEKQLEDQER
210 220 230 240 250
RKQEAYEQLL KEKLMIDEIV RKIYEEDQLE RQQKLEKRNA IQKYIKEFQR
260 270 280 290 300
AQDLWRQKKR EEMEEENRKI LEFAKIQEQR EGERMARVQE SEEKRVQRQN
310 320 330 340 350
LLIQKLEETL RQRDDLERVR QELYLEEYAE FIKLKMKEEV EQRLRKQRDR
360 370 380 390 400
KQDFKDQMAL REVLLQAAKE EEEAFKKAML AKFAEDDRIE LMNAQKQRMK
410 420 430 440 450
QLEHKRAVEK LIEERRNQFL ADKQRELEEL QLQQRRQGCI NEIIEEERLR
460 470 480 490
LLKEHASKLL GYLPKGVFKK EDDVDMLGEE FRKAYQKKSE VCEEKGSS
Length:498
Mass (Da):61,240
Last modified:September 13, 2004 - v1
Checksum:i5E6611EF664B51B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079390 mRNA. Translation: AAH79390.1.
RefSeqiNP_001007753.1. NM_001007752.1.
UniGeneiRn.19338.

Genome annotation databases

EnsembliENSRNOT00000077613; ENSRNOP00000069371; ENSRNOG00000057867.
GeneIDi363093.
KEGGirno:363093.
UCSCiRGD:1549718. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC079390 mRNA. Translation: AAH79390.1.
RefSeqiNP_001007753.1. NM_001007752.1.
UniGeneiRn.19338.

3D structure databases

ProteinModelPortaliQ6AXQ8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000007941.

Proteomic databases

PaxDbiQ6AXQ8.
PRIDEiQ6AXQ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000077613; ENSRNOP00000069371; ENSRNOG00000057867.
GeneIDi363093.
KEGGirno:363093.
UCSCiRGD:1549718. rat.

Organism-specific databases

CTDi55329.
RGDi1549718. Mns1.

Phylogenomic databases

eggNOGiENOG410IFU7. Eukaryota.
ENOG410YXPQ. LUCA.
GeneTreeiENSGT00730000111210.
HOGENOMiHOG000006500.
HOVERGENiHBG108140.
InParanoidiQ6AXQ8.
OMAiGCINEII.
OrthoDBiEOG7D59P3.
PhylomeDBiQ6AXQ8.
TreeFamiTF329219.

Miscellaneous databases

PROiQ6AXQ8.

Gene expression databases

GenevisibleiQ6AXQ8. RN.

Family and domain databases

InterProiIPR026504. MNS1.
[Graphical view]
PANTHERiPTHR19265:SF0. PTHR19265:SF0. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiMNS1_RAT
AccessioniPrimary (citable) accession number: Q6AXQ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: September 13, 2004
Last modified: June 8, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.