Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alpha-1,3-glucosyltransferase

Gene

alg6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiR-DRE-446193. Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein.
UniPathwayiUPA00378.

Protein family/group databases

CAZyiGT57. Glycosyltransferase Family 57.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-1,3-glucosyltransferaseUniRule annotation (EC:2.4.1.-UniRule annotation)
Gene namesi
Name:alg6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 6

Organism-specific databases

ZFINiZDB-GENE-040808-45. alg6.

Subcellular locationi

  • Endoplasmic reticulum membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei110 – 132HelicalUniRule annotationAdd BLAST23
Transmembranei144 – 161HelicalUniRule annotationAdd BLAST18
Transmembranei173 – 197HelicalUniRule annotationAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501014161923 – 227Alpha-1,3-glucosyltransferaseSequence analysisAdd BLAST205

Expressioni

Gene expression databases

BgeeiENSDARG00000017617.
ExpressionAtlasiQ6AXK8. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Belongs to the ALG6/ALG8 glucosyltransferase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2575. Eukaryota.
ENOG410XQK1. LUCA.
GeneTreeiENSGT00550000075073.
HOGENOMiHOG000195048.
HOVERGENiHBG061017.
KOiK03848.

Family and domain databases

InterProiView protein in InterPro
IPR004856. Glyco_trans_ALG6/ALG8.
PANTHERiPTHR12413. PTHR12413. 1 hit.
PfamiView protein in Pfam
PF03155. Alg6_Alg8. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6AXK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENWSLISLC VLLGLTSRWA VSFHSYSGAG KPPMFGDYEA QRHWQELTYN
60 70 80 90 100
LPVHEWYFNT TNNDLNYWGL DYPPLTAYHS LACAYIAKLF NPEWVELHAS
110 120 130 140 150
RGYESHSHKL FMRATVLFAD ALIYIPAVLL YCFYFCDGSP KQKVATAFCI
160 170 180 190 200
LMYPGLMLID YGHFQYNGVS LGLALWGVLG LGLGWDLFGS VAFVLALNYK
210 220
QMELYHALPF FCYLLGKCVK HGLNGQG
Length:227
Mass (Da):25,845
Last modified:September 13, 2004 - v1
Checksum:i5F4B72A98AC83DEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX664614 Genomic DNA. No translation available.
BC079496 mRNA. Translation: AAH79496.1.
RefSeqiNP_001003784.2. NM_001003784.2.
UniGeneiDr.34150.

Genome annotation databases

EnsembliENSDART00000130627; ENSDARP00000108479; ENSDARG00000017617.
GeneIDi445327.
KEGGidre:445327.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ6AXK8_DANRE
AccessioniPrimary (citable) accession number: Q6AXK8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: July 5, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported