SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6AXB7

- Q6AXB7_MOUSE

UniProt

Q6AXB7 - Q6AXB7_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Fragile X mental retardation protein 1 homolog

Gene
Fmr1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. microtubule binding Source: MGI
  2. protein binding Source: MGI
  3. RNA binding Source: Ensembl

GO - Biological processi

  1. central nervous system development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Fragile X mental retardation protein 1 homologImported
Submitted name:
Fragile X mental retardation syndrome 1 homologImported
Gene namesi
Name:Fmr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:95564. Fmr1.

Subcellular locationi

GO - Cellular componenti

  1. cell body Source: MGI
  2. cytoplasmic stress granule Source: MGI
  3. dendritic shaft Source: Ensembl
  4. dendritic spine Source: Ensembl
  5. neuronal ribonucleoprotein granule Source: MGI
  6. nucleus Source: MGI
  7. synapse Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ6AXB7.

Family & Domainsi

Sequence similaritiesi

Contains 2 KH domains.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017033.
HOVERGENiHBG005739.
KOiK15516.
OrthoDBiEOG7NKKJT.
TreeFamiTF105427.

Family and domain databases

Gene3Di3.30.1370.10. 3 hits.
InterProiIPR008395. Agenet-like_dom.
IPR022034. Frag_X_MRP_fam.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
[Graphical view]
PfamiPF05641. Agenet. 1 hit.
PF12235. FXR1P_C. 1 hit.
PF00013. KH_1. 2 hits.
[Graphical view]
SMARTiSM00322. KH. 2 hits.
[Graphical view]
SUPFAMiSSF54791. SSF54791. 2 hits.
PROSITEiPS51641. AGENET_LIKE. 2 hits.
PS50084. KH_TYPE_1. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6AXB7-1 [UniParc]FASTAAdd to Basket

« Hide

MEELVVEVRG SNGAFYKAFV KDVHEDSITV AFENNWQPER QIPFHDVRFP    50
PPVGYNKDIN ESDEVEVYSR ANEKEPCCWW LAKVRMIKGE FYVIEYAACD 100
ATYNEIVTIE RLRSVNPNKP ATKDTFHKIK LEVPEDLRQM CAKESAHKDF 150
KKAVGAFSVT YDPENYQLVI LSINEVTSKR AHMLIDMHFR SLRTKLSLIL 200
RNEEASKQLE SSRQLASRFH EQFIVREDLM GLAIGTHGAN IQQARKVPGV 250
TAIDLDEDTC TFHIYGEDQD AVKKARSFLE FAEDVIQVPR NLVGKVIGKN 300
GKLIQEIVDK SGVVRVRIEA ENEKSVPQEE EIMPPSSLPS NNSRVGPNSS 350
EEKKHLDTKE NTHFSQPNST KVQRVLVVSS IVAGGPQKPE PKAWQGMVPF 400
VFVGTKDSIA NATVLLDYHL NYLKEVDQLR LERLQIDEQL RQIGASSRPP 450
PNRTDKEKGY VTDDGQGMGR GSRPYRNRGH GRRGPGYTSG TNSEASNASE 500
TESDHRDELS DWSLAPTEEE RESFLRRGDG RRRGGGGRGQ GGRGRGGGFK 550
GNDDHSRTDN RPRNPREAKG RTADGSLQSA SSEGSRLRTG KDRNQKKEKP 600
DSVDGLQPLV NGVP 614
Length:614
Mass (Da):68,890
Last modified:September 13, 2004 - v1
Checksum:i122768A6422F6066
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC055766 Genomic DNA. No translation available.
BC079671 mRNA. Translation: AAH79671.1.
RefSeqiNP_001277353.1. NM_001290424.1.
NP_032057.2. NM_008031.3.
UniGeneiMm.3451.

Genome annotation databases

EnsembliENSMUST00000088546; ENSMUSP00000085906; ENSMUSG00000000838.
GeneIDi14265.
KEGGimmu:14265.
UCSCiuc009tiw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC055766 Genomic DNA. No translation available.
BC079671 mRNA. Translation: AAH79671.1 .
RefSeqi NP_001277353.1. NM_001290424.1.
NP_032057.2. NM_008031.3.
UniGenei Mm.3451.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000088546 ; ENSMUSP00000085906 ; ENSMUSG00000000838 .
GeneIDi 14265.
KEGGi mmu:14265.
UCSCi uc009tiw.1. mouse.

Organism-specific databases

CTDi 2332.
MGIi MGI:95564. Fmr1.

Phylogenomic databases

GeneTreei ENSGT00390000017033.
HOVERGENi HBG005739.
KOi K15516.
OrthoDBi EOG7NKKJT.
TreeFami TF105427.

Miscellaneous databases

ChiTaRSi FMR1. mouse.
NextBioi 285619.
SOURCEi Search...

Gene expression databases

Genevestigatori Q6AXB7.

Family and domain databases

Gene3Di 3.30.1370.10. 3 hits.
InterProi IPR008395. Agenet-like_dom.
IPR022034. Frag_X_MRP_fam.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
[Graphical view ]
Pfami PF05641. Agenet. 1 hit.
PF12235. FXR1P_C. 1 hit.
PF00013. KH_1. 2 hits.
[Graphical view ]
SMARTi SM00322. KH. 2 hits.
[Graphical view ]
SUPFAMi SSF54791. SSF54791. 2 hits.
PROSITEi PS51641. AGENET_LIKE. 2 hits.
PS50084. KH_TYPE_1. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ6AXB7_MOUSE
AccessioniPrimary (citable) accession number: Q6AXB7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi