Q6AWJ8 (Q6AWJ8_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LP19005p EMBL AAT94479.1

Gene names

Name:

arr EMBL AAT94479.1 FlyBase FBgn0000119

Organism

Drosophila melanogaster (Fruit fly) EMBL AAT94479.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1246 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Cellular component	Membrane
Domain	EGF-like domain SAAS SAAS000033 Repeat SAAS SAAS000033 Transmembrane Transmembrane helix SAAS SAAS000033
PTM	Disulfide bond SAAS SAAS000033
Gene Ontology (GO)
Biological process	Wnt receptor signaling pathway involved in dorsal/ventral axis specification Inferred from Biological aspect of Ancestor. Source: RefGenome canonical Wnt receptor signaling pathway Inferred from mutant phenotype. Source: FlyBase compound eye morphogenesis Inferred from mutant phenotype. Source: FlyBase nervous system development Inferred from mutant phenotype. Source: FlyBase protein targeting to lysosome Inferred from mutant phenotype. Source: FlyBase regulation of compound eye pigmentation Inferred from mutant phenotype. Source: FlyBase
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from direct assay. Source: FlyBase
Molecular function	Wnt-activated receptor activity Inferred from direct assay. Source: FlyBase Wnt-protein binding Inferred from physical interaction. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6AWJ8 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: F965C3C24D32948B	FASTA	1,246	140,678
	10 20 30 40 50 60 MALEPYTKSA EIEPQLCQVI DNNEDVTTKA TKCTKSNSGV GWRQMLIGFL LICFGISNSW 70 80 90 100 110 120 QYKNVHMPSS SSLIASPPAS AFVNTPATLL FTTRHDIQVA NITRPTGGPQ IDVIVRDLAE 130 140 150 160 170 180 AMAIDFYYAK NLVCWTDSGR EIIECAQTNS SALQPLLRAP KQTVISTGLD KPEGLAMDWY 190 200 210 220 230 240 TDKIYWTDGE KNRIEVATLD GRYQKVLFWT DLDQPRAVAV VPARKLLIWT DWGEYPKIER 250 260 270 280 290 300 ASMDGDPLSR MTLVKEHVFW PNGLAVDLKN ELIYWTDGKH HFIDVMRLDG SSRRTIVNNL 310 320 330 340 350 360 KYPFSLTFYD DRLYWTDWQR GSLNALDLQT RELKELIDTP KAPNSVRAWD PSLQPYEDNP 370 380 390 400 410 420 CAHNNGNCSH LCLLATNSQG FSCACPTGVK LISANTCANG SQEMMFIVQR TQISKISLDS 430 440 450 460 470 480 PDYTIFPLPL GKVKYAIAID YDPVEEHIYW SDVETYTIKR AHADGTGVTD FVTSEVRHPD 490 500 510 520 530 540 GLALDWLARN LYWTDTVTDR IEVCRLDGTA RKVLIYEHLE EPRAIAVAPS LGWMFWSDWN 550 560 570 580 590 600 ERKPKVERAS LDGSERVVLV SENLGWPNGI ALDIEAKAIY WCDGKTDKIE VANMDGSGRR 610 620 630 640 650 660 VVISDNLKHL FGLSILDDYL YWTDWQRRSI DRAHKITGNN RIVVVDQYPD LMGLKVTRLR 670 680 690 700 710 720 EVRGQNACAV RNGGCSHLCL NRPRDYVCRC AIDYELANDK RTCVVPAAFL LFSRQEHIGR 730 740 750 760 770 780 ISIEYNEGNH NDERIPFKDV RDAHALDVSV AERRIYWTDQ KSKCIFRAFL NGSYVQRIVD 790 800 810 820 830 840 SGLIGPDGIA VDWLANNIYW SDAEARRIEV ARLDGSSRRV LLWKGVEEPR SLVLEPRRGY 850 860 870 880 890 900 MYWTESPTDS IRRAAMDGSD LQTIVAGANH AAGLTFDQET RRLYWATQSR PAKIESADWD 910 920 930 940 950 960 GKKRQILVGS DMDEPYAVSL YQDYVYWSDW NTGDIERVHK TTGQNRSLVH SGMTYITSLL 970 980 990 1000 1010 1020 VFNDKRQTGV NPCKVNNGGC SHLCLAQPGR RGMTCACPTH YQLAKDGVSC IPPRNYIIFS 1030 1040 1050 1060 1070 1080 QRNCFGRLLP NTTDCPNIPL PVSGKNIRAV DYDPITHHIY WIEGRSHSIK RSLANGTKVS 1090 1100 1110 1120 1130 1140 LLANSGQPFD LAIDIIGRLL FWTCSQSNSI NVTSFLGESV GVIDTGDSEK PRNIAVHAMK 1150 1160 1170 1180 1190 1200 RLLFWTDVGS HQAIIRARVD GNERVELAYK LEGVTALALD QQSDMIYYAH GKRIDAIDIN 1210 1220 1230 1240 GKNKKTLVSM HISQVINIAA LGGFVYWLDD KTGVERITVN GERRSA

References

[1]	Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Rubin G.M., Celniker S. Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAT94479.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT015250 mRNA. Translation: AAT94479.1.
3D structure databases
ProteinModelPortal	Q6AWJ8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6AWJ8.
Proteomic databases
PRIDE	Q6AWJ8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0000119. arr.
Phylogenomic databases
eggNOG	inNOG07183.
InParanoid	Q6AWJ8.
Gene expression databases
ArrayExpress	Q6AWJ8.
Bgee	Q6AWJ8.
Family and domain databases
InterPro	IPR011042. 6-blade_b-propeller_TolB-like. IPR006210. EGF-like. IPR000033. LDLR_classB_rpt. [Graphical view]
Gene3D	G3DSA:2.120.10.30. 6-blade_b-propeller_TolB-like. 4 hits.
Pfam	PF00058. Ldl_recept_b. 9 hits. [Graphical view]
SMART	SM00181. EGF. 3 hits. SM00135. LY. 20 hits. [Graphical view]
PROSITE	PS51120. LDLRB. 19 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6AWJ8_DROME

Accession

Primary (citable) accession number: Q6AWJ8

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2004
Last sequence update:	September 13, 2004
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)