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Protein
Submitted name:

Dynactin subunit 1

Gene

DCTN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dynactin subunit 1Imported
Gene namesi
Name:DCTN1Imported
Synonyms:DKFZp686E0752Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000204843.12
HGNCiHGNC:2711 DCTN1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204843

PTM / Processingi

Proteomic databases

MaxQBiQ6AWB1
PeptideAtlasiQ6AWB1

Expressioni

Gene expression databases

BgeeiENSG00000204843

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 73CAP-GlyInterPro annotationAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili180 – 315Sequence analysisAdd BLAST136
Coiled coili323 – 346Sequence analysisAdd BLAST24
Coiled coili351 – 503Sequence analysisAdd BLAST153

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0971 Eukaryota
COG5244 LUCA
GeneTreeiENSGT00760000119173
HOGENOMiHOG000015352
HOVERGENiHBG004956

Family and domain databases

Gene3Di2.30.30.190, 1 hit
InterProiView protein in InterPro
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR027663 DCTN1
IPR022157 Dynactin
PANTHERiPTHR18916:SF40 PTHR18916:SF40, 1 hit
PfamiView protein in Pfam
PF01302 CAP_GLY, 1 hit
PF12455 Dynactin, 1 hit
SMARTiView protein in SMART
SM01052 CAP_GLY, 1 hit
SUPFAMiSSF74924 SSF74924, 1 hit
PROSITEiView protein in PROSITE
PS00845 CAP_GLY_1, 1 hit
PS50245 CAP_GLY_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6AWB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAEASARPL RVGSRVEVIG KGHRGTVAYV GATLFATGKW VGVILDEAKG
60 70 80 90 100
KNDGTVQGRK YFTCDEGHGI FVRQSQIQVF EDGADTTSPE TPDSSASKVL
110 120 130 140 150
KREGTDTTAK TSKLPTRPAS TGVAGASSSL GPSGSASAGE LSSSEPSTPA
160 170 180 190 200
QTPLAAPIIP TPVLTSPGAV PPLPSPSKEE EGLRAQVRDL EEKLETLRLK
210 220 230 240 250
RAEDKAKLKE LEKHKIQLEQ VQEWKSKMQE QQADLQRRLK EARKEAKEAL
260 270 280 290 300
EAKERYMEEM ADTADAIEMA TLDKEMAEER AESLQQEVEA LKERVDELTT
310 320 330 340 350
DLEILKAEIE EKGSDGAASS YQLKQLEEQN ARLKDALVRM RDLSSSEKQE
360 370 380 390 400
HVKLQKLMEK KNQELEVVRQ QRERLQEELS QAESTIDELK EQVDAALGAE
410 420 430 440 450
EMVEMLTDRN LNLEEKVREL RETVGDLEAM NEMNDELQEN ARETELELRE
460 470 480 490 500
QLDMAGARVR EAQKRVEAAQ ETVADYQQTI KKYRQLTAHL QDVNRELTNQ
510 520 530 540 550
QEASVERQQQ PPPETFDFKI KFAETKAHAK AIEMELRQME VAQANRHMSL
560 570 580 590 600
LTAFMPDSFL RPGGDHDCVL VLLLMPRLIC KAELIRKQAQ EKFELSENCS
610 620 630 640 650
ERPGLRGAAG EQLSFAAGLV YSLSLLQATL HRYEHALSQC SVDVYKKVGS
660 670 680 690 700
LYPEMSAHER SLDFLIELLH KDQLDETVNV EPLTKAIKYY QHLYSIHLAE
710 720 730 740 750
QPEDCTMQLA DHIKFTQSAL DCMSVEVGRL RAFLQGGQEA TDIALLLRDL
760 770 780 790 800
ETSCSDIRQF CKKIRRRMPG TDAPGIPAAL AFGPQVSDTL LDCRKHLTWV
810 820 830 840 850
VAVLQEVAAA AAQLIAPLAE NEGLLVAALE ELAFKASEQV GLDGWVEGVG
860 870 880 890
RVSDQCGAFT SALGSCRSMG PPPAAPMSVC ASHATSSSVP
Length:890
Mass (Da):98,518
Last modified:September 13, 2004 - v1
Checksum:iE8112675DFEC7552
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005041 Genomic DNA No translation available.
BX647972 mRNA Translation: CAH10572.1
UniGeneiHs.516111

Genome annotation databases

EnsembliENST00000434055; ENSP00000416711; ENSG00000204843
UCSCiuc061ktn.1 human

Similar proteinsi

Entry informationi

Entry nameiQ6AWB1_HUMAN
AccessioniPrimary (citable) accession number: Q6AWB1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2004
Last sequence update: September 13, 2004
Last modified: April 25, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health