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Protein

Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic

Gene

Os03g0617900

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH.

Pathwayi: L-arginine biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes N(2)-acetyl-L-ornithine from L-glutamate.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. Arginine biosynthesis bifunctional protein ArgJ, chloroplastic (Os03g0279400), Arginine biosynthesis bifunctional protein ArgJ, chloroplastic (OsJ_10355)
  2. no protein annotated in this organism
  3. Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic (Os03g0617900)
  4. no protein annotated in this organism
This subpathway is part of the pathway L-arginine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes N(2)-acetyl-L-ornithine from L-glutamate, the pathway L-arginine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei219By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00068; UER00108.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic (EC:1.2.1.38)
Short name:
AGPR
Alternative name(s):
N-acetyl-glutamate semialdehyde dehydrogenase
Short name:
NAGSA dehydrogenase
Gene namesi
Ordered Locus Names:Os03g0617900, LOC_Os03g42110
ORF Names:OSJNBa0063J18.8
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 3

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 74ChloroplastSequence analysisAdd BLAST74
ChainiPRO_000024761075 – 415Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplasticAdd BLAST341

Proteomic databases

PaxDbiQ6AV34.
PRIDEiQ6AV34.

Expressioni

Gene expression databases

GenevisibleiQ6AV34. OS.

Interactioni

Subunit structurei

Homotetramer.1 Publication

Protein-protein interaction databases

STRINGi39947.LOC_Os03g42110.1.

Structurei

Secondary structure

1415
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi73 – 79Combined sources7
Helixi83 – 92Combined sources10
Beta strandi96 – 104Combined sources9
Turni107 – 110Combined sources4
Helixi113 – 116Combined sources4
Helixi118 – 120Combined sources3
Helixi131 – 133Combined sources3
Helixi136 – 138Combined sources3
Beta strandi140 – 144Combined sources5
Beta strandi147 – 149Combined sources3
Helixi150 – 156Combined sources7
Beta strandi163 – 166Combined sources4
Turni170 – 172Combined sources3
Helixi176 – 183Combined sources8
Helixi190 – 193Combined sources4
Helixi201 – 210Combined sources10
Beta strandi212 – 215Combined sources4
Helixi219 – 233Combined sources15
Beta strandi239 – 241Combined sources3
Beta strandi243 – 249Combined sources7
Helixi250 – 253Combined sources4
Helixi259 – 261Combined sources3
Helixi263 – 266Combined sources4
Helixi280 – 292Combined sources13
Beta strandi299 – 309Combined sources11
Beta strandi311 – 319Combined sources9
Helixi325 – 336Combined sources12
Beta strandi342 – 344Combined sources3
Helixi353 – 355Combined sources3
Turni356 – 358Combined sources3
Beta strandi362 – 368Combined sources7
Beta strandi374 – 381Combined sources8
Turni383 – 388Combined sources6
Helixi389 – 400Combined sources12
Turni404 – 407Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CVOX-ray2.20A/B/C/D50-415[»]
ProteinModelPortaliQ6AV34.
SMRiQ6AV34.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6AV34.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG4354. Eukaryota.
COG0002. LUCA.
HOGENOMiHOG000254904.
InParanoidiQ6AV34.
KOiK00145.
OMAiTFVPHLT.
OrthoDBiEOG09360B0T.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00150. ArgC_type1. 1 hit.
InterProiIPR023013. AGPR_AS.
IPR000706. AGPR_type-1.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
IPR012280. Semialdhyde_DH_dimer_dom.
[Graphical view]
PfamiPF01118. Semialdhyde_dh. 1 hit.
PF02774. Semialdhyde_dhC. 1 hit.
[Graphical view]
SMARTiSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01850. argC. 1 hit.
PROSITEiPS01224. ARGC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6AV34-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSTALGGGA PARLGLAPKD GVFGSNLKQC GGFMLKTTPK VGSSSVRVRA
60 70 80 90 100
SVASSPQKQH SPKTSGVKSG EEVRIAVLGA SGYTGAEIVR LLANHPQFRI
110 120 130 140 150
KVMTADRKAG EQFGSVFPHL ITQDLPNLVA VKDADFSNVD AVFCCLPHGT
160 170 180 190 200
TQEIIKGLPQ ELKIVDLSAD FRLRDINEYA EWYGHSHRAP ELQQEAVYGL
210 220 230 240 250
TEVLRNEIRN ARLVANPGCY PTSIQLPLVP LIKAKLIKVS NIIIDAKSGV
260 270 280 290 300
SGAGRGAKEA NLYTEIAEGI HAYGIKGHRH VPEIEQGLSE AAESKVTISF
310 320 330 340 350
TPNLICMKRG MQSTMFVEMA PGVTANDLYQ HLKSTYEGEE FVKLLNGSSV
360 370 380 390 400
PHTRHVVGSN YCFMNVFEDR IPGRAIIISV IDNLVKGASG QAVQNLNLMM
410
GLPENTGLQY QPLFP
Length:415
Mass (Da):44,786
Last modified:September 13, 2004 - v1
Checksum:i7AD9E6788B065016
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107206 Genomic DNA. Translation: AAT77050.1.
DP000009 Genomic DNA. Translation: ABF97646.1.
AP008209 Genomic DNA. Translation: BAF12582.1.
AP014959 Genomic DNA. Translation: BAS85284.1.
AK071544 mRNA. Translation: BAG92548.1.
RefSeqiXP_015632676.1. XM_015777190.1.
UniGeneiOs.16888.

Genome annotation databases

EnsemblPlantsiOS03T0617900-01; OS03T0617900-01; OS03G0617900.
GeneIDi4333458.
GrameneiOS03T0617900-01; OS03T0617900-01; OS03G0617900.
KEGGiosa:4333458.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107206 Genomic DNA. Translation: AAT77050.1.
DP000009 Genomic DNA. Translation: ABF97646.1.
AP008209 Genomic DNA. Translation: BAF12582.1.
AP014959 Genomic DNA. Translation: BAS85284.1.
AK071544 mRNA. Translation: BAG92548.1.
RefSeqiXP_015632676.1. XM_015777190.1.
UniGeneiOs.16888.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CVOX-ray2.20A/B/C/D50-415[»]
ProteinModelPortaliQ6AV34.
SMRiQ6AV34.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os03g42110.1.

Proteomic databases

PaxDbiQ6AV34.
PRIDEiQ6AV34.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS03T0617900-01; OS03T0617900-01; OS03G0617900.
GeneIDi4333458.
GrameneiOS03T0617900-01; OS03T0617900-01; OS03G0617900.
KEGGiosa:4333458.

Phylogenomic databases

eggNOGiKOG4354. Eukaryota.
COG0002. LUCA.
HOGENOMiHOG000254904.
InParanoidiQ6AV34.
KOiK00145.
OMAiTFVPHLT.
OrthoDBiEOG09360B0T.

Enzyme and pathway databases

UniPathwayiUPA00068; UER00108.

Miscellaneous databases

EvolutionaryTraceiQ6AV34.

Gene expression databases

GenevisibleiQ6AV34. OS.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00150. ArgC_type1. 1 hit.
InterProiIPR023013. AGPR_AS.
IPR000706. AGPR_type-1.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
IPR012280. Semialdhyde_DH_dimer_dom.
[Graphical view]
PfamiPF01118. Semialdhyde_dh. 1 hit.
PF02774. Semialdhyde_dhC. 1 hit.
[Graphical view]
SMARTiSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01850. argC. 1 hit.
PROSITEiPS01224. ARGC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARGC_ORYSJ
AccessioniPrimary (citable) accession number: Q6AV34
Secondary accession number(s): Q10GQ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: September 13, 2004
Last modified: November 30, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.