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Protein

Probable protein phosphatase 2C 47

Gene

Os05g0134200

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi120 – 1201Manganese 1By similarity
Metal bindingi120 – 1201Manganese 2By similarity
Metal bindingi121 – 1211Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi294 – 2941Manganese 2By similarity
Metal bindingi337 – 3371Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiREACT_225339. Regulation of AMPK activity via LKB1.
REACT_248492. ISG15 antiviral mechanism.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 47 (EC:3.1.3.16)
Short name:
OsPP2C47
Gene namesi
Ordered Locus Names:Os05g0134200, LOC_Os05g04360
ORF Names:OSJNBa0077L08.15, P0519E07.3
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 5

Organism-specific databases

GrameneiQ6AUQ4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Probable protein phosphatase 2C 47PRO_0000363294Add
BLAST

Proteomic databases

PRIDEiQ6AUQ4.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os05g04360.1.

Structurei

3D structure databases

ProteinModelPortaliQ6AUQ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini75 – 339265PP2C-likeAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi31 – 377Poly-Ala

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ6AUQ4.
KOiK14803.
OMAiEVQYHRC.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6AUQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAEAEVMHQ PVPVLEVPYH RCVAKGVEEV AAAAAVAPPP VVEVEVAVQV
60 70 80 90 100
PHMGLESAAG APSISVDALQ FVPSIRSGSF ADIGPRRYME DEHIRIDDLS
110 120 130 140 150
AHLGSLLVCP LPSAFYGVFD GHGGLDAAAY MKRHAMRFLF EDSEFPQASQ
160 170 180 190 200
VDETYVQSVE NSVRRAFLQA DLALADDLDI SRSSGTTALT ALVFGRQLLV
210 220 230 240 250
ANAGDCRAVL CRRGVAMEMS RDHRANYAEE CERVAASGGY IEDGYLNGVL
260 270 280 290 300
SVTRALGDWD MKMPDGSISP LIAEPEFRQT MLTEDDEFLI MGCDGIWDVM
310 320 330 340 350
TSQHAVSIVR RGLRQHDDPE RCARELVMEA KRLETADNLT VIVVCFVSEL
360 370 380
GSPRQEQVGG QAGVARPRSC KSLSAEALCN LRSWLETDR
Length:389
Mass (Da):42,379
Last modified:September 13, 2004 - v1
Checksum:iD522A46845B1E6AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC118288 Genomic DNA. Translation: AAT85179.1.
AC087552 Genomic DNA. Translation: AAT94045.1.
AP008211 Genomic DNA. Translation: BAF16479.1.
AK067074 mRNA. Translation: BAG90254.1.
RefSeqiNP_001054565.1. NM_001061100.1.
UniGeneiOs.9653.

Genome annotation databases

EnsemblPlantsiOS05T0134200-01; OS05T0134200-01; OS05G0134200.
GeneIDi4337723.
KEGGiosa:4337723.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC118288 Genomic DNA. Translation: AAT85179.1.
AC087552 Genomic DNA. Translation: AAT94045.1.
AP008211 Genomic DNA. Translation: BAF16479.1.
AK067074 mRNA. Translation: BAG90254.1.
RefSeqiNP_001054565.1. NM_001061100.1.
UniGeneiOs.9653.

3D structure databases

ProteinModelPortaliQ6AUQ4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os05g04360.1.

Proteomic databases

PRIDEiQ6AUQ4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS05T0134200-01; OS05T0134200-01; OS05G0134200.
GeneIDi4337723.
KEGGiosa:4337723.

Organism-specific databases

GrameneiQ6AUQ4.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ6AUQ4.
KOiK14803.
OMAiEVQYHRC.

Enzyme and pathway databases

ReactomeiREACT_225339. Regulation of AMPK activity via LKB1.
REACT_248492. ISG15 antiviral mechanism.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C47_ORYSJ
AccessioniPrimary (citable) accession number: Q6AUQ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: September 13, 2004
Last modified: January 7, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.