Q6AS28 (SYGA_DESPS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	DP0118

Organism

Desulfotalea psychrophila [Complete proteome] [HAMAP]

Taxonomic identifier

84980 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfobacterales › Desulfobulbaceae › Desulfotalea

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 290	290	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000047415

Sequences

	Sequence		Length	Mass (Da)
	Q6AS28 [UniParc]. Last modified September 13, 2004. Version 1. Checksum: 21856076BE83A74D	FASTA	290	33,533
	10 20 30 40 50 60 MNFQNIIFEL NNYWAEQGCV VQQPYDMEVG AGTFHPATLL RSLGPEPWKA AYAQPSRRPT 70 80 90 100 110 120 DGRYGENPNR LQHYYQYQVV MKPSPLNIQE LYLGSLKRFG LNLLEHDIRF VEDDWESPTL 130 140 150 160 170 180 GASGLGWEIW LDGMEISQFT YFQQAGSIDL TPTTVEITYG LERIAMYLQG VESVYDIAWN 190 200 210 220 230 240 DEVTYGEIFH QAEVEFSTFN FEEANVEKLT DFFNSFEEEA HKLIAKKLIL PAYDYCLKCS 250 260 270 280 290 HTFNLLDARK AISVTERTRY IGRIRNIARG VAEQYVIQRA ELGHPLIKNK

References

[1]

"The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments." Rabus R., Ruepp A., Frickey T., Rattei T., Fartmann B., Stark M., Bauer M., Zibat A., Lombardot T., Becker I., Amann J., Gellner K., Teeling H., Leuschner W.D., Gloeckner F.-O., Lupas A.N., Amann R., Klenk H.-P. Environ. Microbiol. 6:887-902(2004) [PubMed: 15305914] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LSv54 / DSM 12343.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR522870 Genomic DNA. Translation: CAG34847.1.
RefSeq	YP_063854.1. NC_006138.1.
3D structure databases
HSSP	HSSP built from PDB template 1J5W based on UniProtKB Q9WY59.
ProteinModelPortal	Q6AS28.
SMR	Q6AS28. Positions 1-276.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2946244.
GenomeReviews	Gene locus DP0118 in contig CR522870_GR.
KEGG	dps:DP0118.
NMPDR	fig|177439.1.peg.118.
PATRIC	21709749. VBIDesPsy67261_0130.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285316.
OMA	CRRPTDG.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	DPSY177439:DP0118-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_DESPS

Accession

Primary (citable) accession number: Q6AS28

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2004
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program