Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot Q6ARF1 (NRFA_DESPS)

Last modified November 4, 2008. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Cytochrome c-552
    EC=1.7.2.2
Alternative name(s):
    Ammonia-forming cytochrome c nitrite reductase
      Short name=Cytochrome c nitrite reductase
Gene names
Name: nrfA
Ordered Locus Names: DP0344
OrganismDesulfotalea psychrophila [Complete proteome] [HAMAP]
Taxonomic identifier84980 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfobacterales › Desulfobulbaceae › Desulfotalea

Hide | Top

Protein attributes

Sequence length508 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Function

Plays a role in nitrite reduction By similarity.

Catalytic activity

NH(3) + 2 H(2)O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H(+).

Cofactor

Binds 1 calcium ion per monomer By similarity.

Binds 5 heme groups covalently per monomer By similarity.

Pathway

Nitrogen metabolism; nitrate reduction (assimilation).

Subcellular location

PeriplasmBy similarity.

Sequence similarities

Belongs to the cytochrome c-552 family.

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 508485Cytochrome c-552
PRO_0000268961

Sites

Metal binding1031Iron (heme 3 axial ligand) By similarity
Metal binding1351Iron (heme 1 axial ligand) By similarity
Metal binding1731Iron (heme 2 axial ligand) By similarity
Metal binding2151Iron (heme 3 axial ligand) By similarity
Metal binding2171Calcium By similarity
Metal binding2181Calcium; via carbonyl oxygen By similarity
Metal binding2741Calcium; via carbonyl oxygen By similarity
Metal binding2761Calcium By similarity
Metal binding2881Iron (heme 5 axial ligand) By similarity
Metal binding2991Iron (heme 4 axial ligand) By similarity
Metal binding3131Iron (heme 2 axial ligand) By similarity
Metal binding3301Iron (heme 5 axial ligand) By similarity
Metal binding4051Iron (heme 4 axial ligand) By similarity
Binding site1311Heme 1 (covalent) By similarity
Binding site1341Heme 1 (covalent) By similarity
Binding site1691Heme 2 (covalent) By similarity
Binding site1721Heme 2 (covalent) By similarity
Binding site2111Heme 3 (covalent) By similarity
Binding site2141Heme 3 (covalent) By similarity
Binding site2181Substrate By similarity
Binding site2771Substrate By similarity
Binding site2951Heme 4 (covalent) By similarity
Binding site2981Heme 4 (covalent) By similarity
Binding site3261Heme 5 (covalent) By similarity
Binding site3291Heme 5 (covalent) By similarity

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q6ARF1-1 [UniParc].

Last modified September 13, 2004. Version 1.
Checksum: B1BCB2554092EF97

FASTA50856,824
        10         20         30         40         50         60 
MNKSYKILLT GSVIAIGAMG LMANSINSRE AERKEINTGP VVQAEGVASK NEEWYRYYPR 

        70         80         90        100        110        120 
EYDSWKQTKK SDKITDLLRE KPQLAIIWAG YGFAKDYNAP RGHFYAIQDN INTLRTGAPT 

       130        140        150        160        170        180 
GPSNGPMPTA CWTCKSPDVP RLMDEVGENE FFTGKWAKYG NQIVNPIGCA DCHNSQTGNL 

       190        200        210        220        230        240 
GFSRPHLGRA LEASGVNLDE ITFQDMRTLV CAQCHVEYYF RPTEWTDKTG KTKTAKVVTL 

       250        260        270        280        290        300 
PWAKGLSAEN MEEYYDEYSF KDWTHKISKA PMLKAQHPGY ELFSKGIHAQ NGVSCADCHM 

       310        320        330        340        350        360 
PYKQQGSIKY TDHNIGNPLD DIASTCLTCH RDSEKAFRDR VASKLERKEQ LMKMAMDTLA 

       370        380        390        400        410        420 
AAHLEAGKAW ELGATEAEMQ PVLELLRSGQ WLWDYSIASH GSFFHSPEET LRLLGVANDK 

       430        440        450        460        470        480 
GGKARIKLAA ILAQHGLIGY QVPDFSTKEK AQALAGVPLQ KLITEKKAFE STLLEQWNEE 

       490        500 
AVKAGRLDPK TLEGMSNKSS WSQTELSQ

« Hide

Hide | Top

References

[1]"The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments."
Rabus R., Ruepp A., Frickey T., Rattei T., Fartmann B., Stark M., Bauer M., Zibat A., Lombardot T., Becker I., Amann J., Gellner K., Teeling H., Leuschner W.D., Gloeckner F.-O., Lupas A.N., Amann R., Klenk H.-P.
Environ. Microbiol. 6:887-902(2004) [PubMed: 15305914] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LSv54 / DSM 12343.

Hide | Top

Cross-references

Sequence databases

CR522870 Genomic DNA. Translation: CAG35073.1.
RefSeqYP_064080.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2946323.
GenomeReviewsGene locus DP0344 in contig CR522870_GR.
KEGGdps:DP0344.
NMPDRfig|177439.1.peg.344.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ6ARF1.

Enzyme and pathway databases

BioCycDPSY177439:DP0344-MON.

Family and domain databases

HAMAPMF_01182.
[Tree]
InterProIPR003321. Cyt_c552.
IPR011031. Multihaem_cyt.
[Graphical view]
PfamPF02335. Cytochrom_C552. 1 hit.
[Graphical view]
PIRSFPIRSF000243. Cyt_c552. 1 hit.
PROSITEPS51008. MULTIHEME_CYTC. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameNRFA_DESPS
AccessionPrimary (citable) accession number: Q6ARF1
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 13, 2004
Last modified: November 4, 2008
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents