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Q6AQ48

- G6PI_DESPS

UniProt

Q6AQ48 - G6PI_DESPS

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Desulfotalea psychrophila (strain LSv54 / DSM 12343)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 2 (29 Mar 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei356 – 3561Proton donorUniRule annotation
    Active sitei387 – 3871UniRule annotation
    Active sitei502 – 5021UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciDPSY177439:GJW5-823-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:DP0796
    OrganismiDesulfotalea psychrophila (strain LSv54 / DSM 12343)
    Taxonomic identifieri177439 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobulbaceaeDesulfotalea
    ProteomesiUP000000602: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 534534Glucose-6-phosphate isomerasePRO_0000180638Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi177439.DP0796.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6AQ48.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OMAiRAHYVSN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6AQ48-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFASYKSIQE TCAFEKLSEL AQSPYDLTQP GALQADNRLQ RYQVAGQAFK    50
    LFYATEQVDD RVLAGLQAVA DECQLVSQYR AMRTGAVMNK IDGFVSENRR 100
    VLHTATRDLF SGEPAEASMN SRAKRELEKL SHFLDALDAG EIVNEAGEAF 150
    TTIVQVGIGG SDLGPRAVYE ALKSYTIVGR RAAFISNVDP DDVSMALADL 200
    DLGKTIFNIV SKSGSTLETV TNEAFVRRAL LENGYDSARH CISITGEGSP 250
    MDDPDSYLAS FYLYDCIGGR YSTTSMVGCV LLGFTLGFEQ VMAFLRGAAN 300
    MDNSADEVDI LKNIPLLMAL IGIWNRNFLD LSSLAIIPYS QALYRFPAHL 350
    QQCDMESNGK SVDRQGRAVQ GKTGPIIWGE TGSNSQHAFF QHIYQGTSPV 400
    PIEFIGFSES QRGKDIEVQG CTSQQKLLAN LFAQMVALAC GKKDQNLNKF 450
    FAGNRPSCLL FAKKLTPYVM GSLLACYEAK IVFQGFAWNI NSFDQEGVQL 500
    GKELAKRFLR EIGGEEEGFH GIESAFLNEV QRGV 534
    Length:534
    Mass (Da):58,681
    Last modified:March 29, 2005 - v2
    Checksum:i658C7A34EC605102
    GO

    Sequence cautioni

    The sequence CAG35525.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR522870 Genomic DNA. Translation: CAG35525.1. Different initiation.
    RefSeqiYP_064532.1. NC_006138.1.

    Genome annotation databases

    EnsemblBacteriaiCAG35525; CAG35525; DP0796.
    GeneIDi2945586.
    KEGGidps:DP0796.
    PATRICi21711259. VBIDesPsy67261_0861.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR522870 Genomic DNA. Translation: CAG35525.1 . Different initiation.
    RefSeqi YP_064532.1. NC_006138.1.

    3D structure databases

    ProteinModelPortali Q6AQ48.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 177439.DP0796.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAG35525 ; CAG35525 ; DP0796 .
    GeneIDi 2945586.
    KEGGi dps:DP0796.
    PATRICi 21711259. VBIDesPsy67261_0861.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OMAi RAHYVSN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci DPSY177439:GJW5-823-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LSv54 / DSM 12343.

    Entry informationi

    Entry nameiG6PI_DESPS
    AccessioniPrimary (citable) accession number: Q6AQ48
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: March 29, 2005
    Last modified: October 1, 2014
    This is version 65 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3