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Protein

Adenine deaminase 1

Gene

ade1

Organism
Desulfotalea psychrophila (strain LSv54 / DSM 12343)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciDPSY177439:GJW5-1421-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminase 1UniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
Adenase 1UniRule annotation
Short name:
Adenine aminase 1UniRule annotation
Gene namesi
Name:ade1UniRule annotation
Ordered Locus Names:DP1373
OrganismiDesulfotalea psychrophila (strain LSv54 / DSM 12343)
Taxonomic identifieri177439 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobulbaceaeDesulfotalea
Proteomesi
  • UP000000602 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 594594Adenine deaminase 1PRO_0000142417Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi177439.DP1373.

Structurei

3D structure databases

ProteinModelPortaliQ6ANH2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiSYELREH.
OrthoDBiEOG622PNM.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6ANH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVSKDALKQ LIRAGRGVIP ASKVLEGGYL VNVMSNEVYL ADVAIYEERI
60 70 80 90 100
VAIGKVEEYK GPETEVIDVT GLYLLPGLID GHLHSECSKL SITSFAKAVV
110 120 130 140 150
PCGTTSIVSG LDEYISVSGL EGLQEVFKEV KKSPLKVFWG APYKTPYTFP
160 170 180 190 200
KSTVAFNFTE EVHQEVQQWP ECFGVWETVR EAVQEEDEDT LGALATAQNN
210 220 230 240 250
RLPIFGCAPM ARGKELNGYL CAGVRLDHES YDHEEVVEKM RNGMHMLIRE
260 270 280 290 300
SSVTHFLEEN IRAVTEVNPY LARRVSFCTD DVTATDILEK GHMDNVVRQA
310 320 330 340 350
IKAGVEPITA IQMATINSAE AYRIDHLVGS ITPGKIADIV MVDSLEGFQV
360 370 380 390 400
QAVLTDGKLV ARDKKMSYEL KAPARSSVLS CALKCATTTP EDFQYRVEIE
410 420 430 440 450
QGTAEVLSMN VKGPFVRKRR DVTLQVANHI VQADTENDVL MVSVLERFGR
460 470 480 490 500
NGNKSLAFCS GWKLKKGAMA SSAAPDDNNI IVMGADASDM SIAVNHLIEN
510 520 530 540 550
GGGQVIVADG EILEFLALPV GGIVSDLEAE EIARQESLLT KAANSLGCDL
560 570 580 590
PDPLMYMFFL PITAIPDYAI TDVGPVDCIA LTTFDPILAL NPGK
Length:594
Mass (Da):64,784
Last modified:September 13, 2004 - v1
Checksum:i28D5BE1046AF2FC6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR522870 Genomic DNA. Translation: CAG36102.1.
RefSeqiWP_011188614.1. NC_006138.1.

Genome annotation databases

EnsemblBacteriaiCAG36102; CAG36102; DP1373.
KEGGidps:DP1373.
PATRICi21712553. VBIDesPsy67261_1486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR522870 Genomic DNA. Translation: CAG36102.1.
RefSeqiWP_011188614.1. NC_006138.1.

3D structure databases

ProteinModelPortaliQ6ANH2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi177439.DP1373.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAG36102; CAG36102; DP1373.
KEGGidps:DP1373.
PATRICi21712553. VBIDesPsy67261_1486.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiSYELREH.
OrthoDBiEOG622PNM.

Enzyme and pathway databases

BioCyciDPSY177439:GJW5-1421-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LSv54 / DSM 12343.

Entry informationi

Entry nameiADEC1_DESPS
AccessioniPrimary (citable) accession number: Q6ANH2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: September 13, 2004
Last modified: November 11, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.