Q6ALZ3 (LFTR_DESPS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase
EC=2.3.2.6

Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase

Gene names

Name:	aat
Ordered Locus Names:	DP1903

Organism

Desulfotalea psychrophila (strain LSv54 / DSM 12343) [Complete proteome] [HAMAP]

Taxonomic identifier

177439 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfobacterales › Desulfobulbaceae › Desulfotalea › Desulfotalea psychrophila

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity. HAMAP-Rule MF_00688
Catalytic activity	L-leucyl-tRNA + protein = tRNA + L-leucyl-protein. HAMAP-Rule MF_00688 L-phenylalanyl-tRNA + protein = tRNA + L-phenylalanyl-protein. HAMAP-Rule MF_00688
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00688.
Sequence similarities	Belongs to the L/F-transferase family.
Sequence caution	The sequence CAG36632.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	leucyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 227	227	Leucyl/phenylalanyl-tRNA--protein transferase HAMAP-Rule MF_00688		PRO_0000207215

Sequences

	Sequence		Length	Mass (Da)
	Q6ALZ3 [UniParc]. Last modified October 31, 2006. Version 2. Checksum: 81A2C4B9A9476D24	FASTA	227	25,990
	10 20 30 40 50 60 NMTVFRLNRD CTFPHPKHAE SDGLLAVGGD LSAKRLINGY RDGIFPWYSE GDPILWWYTH 70 80 90 100 110 120 PRFVIYPDRF TAGKRLMRYW KKTSYTFTID QAFSQVIGLC GSSRTGRGEE TWILPEMREA 130 140 150 160 170 180 YGQLHELGYA HSVECWDVDR LVGGLYGVEL GGVFFGESMF STVSNSSKFC LIYLVEQARK 190 200 210 220 RGVQLIDCQM TTRHLLQFGA VEISGEKFYQ HLQLLIADIG PQPAWKI

References

[1]

"The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments." Rabus R., Ruepp A., Frickey T., Rattei T., Fartmann B., Stark M., Bauer M., Zibat A., Lombardot T., Becker I., Amann J., Gellner K., Teeling H., Leuschner W.D., Gloeckner F.-O., Lupas A.N., Amann R., Klenk H.-P. Environ. Microbiol. 6:887-902(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LSv54 / DSM 12343.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR522870 Genomic DNA. Translation: CAG36632.1. Different initiation.
RefSeq	YP_065639.1. NC_006138.1.
3D structure databases
ProteinModelPortal	Q6ALZ3.
ModBase	Search...
Protein-protein interaction databases
STRING	177439.DP1903.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAG36632; CAG36632; DP1903.
GeneID	2944389.
KEGG	dps:DP1903.
PATRIC	21713736. VBIDesPsy67261_2064.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2360.
HOGENOM	HOG000102325.
KO	K00684.
OMA	MFYGESM.
ProtClustDB	PRK00301.
Enzyme and pathway databases
BioCyc	DPSY177439:GJW5-1964-MONOMER.
Family and domain databases
HAMAP	MF_00688. Leu_Phe_trans.
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR004616. Leu/Phe-tRNA_Trfase. [Graphical view]
Pfam	PF03588. Leu_Phe_trans. 1 hit. [Graphical view]
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR00667. aat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LFTR_DESPS

Accession

Primary (citable) accession number: Q6ALZ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	October 31, 2006
Last modified:	May 29, 2013
This is version 53 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program